InAADR

Drug Information

Drug Name: Felodipine (72509-76-3)
PubChem ID: 3333
SMILES: CCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C
InchiKey: RZTAMFZIAATZDJ-UHFFFAOYSA-N
Therapeutic Category: Anti-Arrhythmia Agents, Antihypertensive Agents, Calcium Channel Blockers, Cardiovascular Agents, Membrane Transport Modulators, Vasodilator Agents

Computed Drug Properties

Molecular Weight (dalton): 384.259
LogP: 3.9643
Ring Count: 1
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 64.63

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension MetaADEDB
Abdominal Hernia MetaADEDB
Abdominal Pain ADReCS
Abdominal Pain MetaADEDB
Aching Joints MetaADEDB
Aching Muscles MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Kidney Failure MetaADEDB
Acute Leukaemia MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Respiratory Failure MetaADEDB
Adrenal Mass MetaADEDB
Adrenocortical Insufficiency Acute MetaADEDB
Afib MetaADEDB
Ageusia MetaADEDB
Alanine Aminotransferase Increased ADReCS
Aldolase Increased MetaADEDB
Anaemia ADReCS
Anaemia Postoperative MetaADEDB
Angina Pectoris ADReCS
Angina Unstable MetaADEDB
Angioedema ADReCS
Angle Closure Glaucoma MetaADEDB
Anxiety ADReCS
Anxiety Disorder ADReCS
Aortic Dilatation MetaADEDB
Aortic Regurgitation MetaADEDB
Apathy MetaADEDB
Aphthous Stomatitis MetaADEDB
Arrhythmia ADReCS
Arterial Disorder MetaADEDB
Arterial Occlusive Disease MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthralgia ADReCS
Asthenia ADReCS
Back Pain ADReCS
Barrett Oesophagus MetaADEDB
Belching MetaADEDB
Benign Prostatic Hyperplasia MetaADEDB
Bile Duct Stone MetaADEDB
Bladder Neck Obstruction MetaADEDB
Bladder Retention MetaADEDB
Blepharospasm MetaADEDB
Blood Calcium MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Phosphorus Decreased MetaADEDB
Blood Phosphorus Increased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Abnormal MetaADEDB
Blood Sodium MetaADEDB
Blood Uric Acid ADReCS
Blurred Vision MetaADEDB
Body Temperature Increased ADReCS
Brachial Plexopathy MetaADEDB
Bradycardia ADReCS
Bradypnoea MetaADEDB
Breast Calcifications MetaADEDB
Breast Cancer MetaADEDB
Breast Fibrosis MetaADEDB
Breast Lump MetaADEDB
Breast Lump Removal MetaADEDB
Bronchitis ADReCS
Bruise MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Pacemaker Insertion MetaADEDB
Cellulitis MetaADEDB
Cerebral Artery Occlusion MetaADEDB
Chest Pain ADReCS
Cholangiolitis MetaADEDB
Cholecystitis MetaADEDB
Cholecystitis Acute MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Chronic Sinusitis MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Cold Extremities MetaADEDB
Colitis Pseudomembranous MetaADEDB
Condition Aggravated MetaADEDB
Confusional State ADReCS
Congenital Tricuspid Valve Incompetence MetaADEDB
Constipation ADReCS
Contusion ADReCS
Coombs Direct Test Positive MetaADEDB
Coordination Abnormal MetaADEDB
Coronary Artery Occlusion MetaADEDB
Coronary Disease MetaADEDB
Cough ADReCS
Coxalgia SIDER
Cramp Muscle SIDER
Cutaneous Ulcer MetaADEDB
Cyst MetaADEDB
Deafness MetaADEDB
Deafness Congenital MetaADEDB
Demyelination MetaADEDB
Dental Abscess MetaADEDB
Depression ADReCS
Dermatitis ADReCS
Dermatosis MetaADEDB
Device Malfunction MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Acidosis MetaADEDB
Diabetic Complication MetaADEDB
Diabetic Foot MetaADEDB
Diabetic Neuropathy MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Dilatation Atrial MetaADEDB
Dilatation Ventricular MetaADEDB
Discomfort ADReCS
Disorder Renal MetaADEDB
Disturbance In Sexual Arousal ADReCS
Diverticulitis MetaADEDB
Diverticulum MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Dressler Syndrome MetaADEDB
Drop Attacks MetaADEDB
Drug Effect Increased MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Interaction MetaADEDB
Dry Mouth ADReCS
Duodenal Ulcer Perforation MetaADEDB
Duodenitis MetaADEDB
Dyspepsia ADReCS
Dyspnoea ADReCS
Dysstasia MetaADEDB
Dysuria ADReCS
Edema MetaADEDB
Edema Extremities MetaADEDB
Effusion MetaADEDB
Electrocardiogram T Wave Abnormal MetaADEDB
Electrolyte Disorder MetaADEDB
Elevated Erythrocyte Sedimentation Rate MetaADEDB
Elevated Prostate Specific Antigen MetaADEDB
Emesis MetaADEDB
Emphysema MetaADEDB
Encephalitis Allergic MetaADEDB
Endocarditis Enterococcal MetaADEDB
Epidural Hematoma MetaADEDB
Epistaxis ADReCS
Erectile Dysfunction ADReCS
Erythema ADReCS
Erythema Multiforme ADReCS
Erythema Nodosum ADReCS
Ethmoid Sinus Surgery MetaADEDB
Excess Potassium MetaADEDB
External Ear Pain MetaADEDB
Extraskeletal Ossification MetaADEDB
Extrasystoles ADReCS
Extremity Pain MetaADEDB
Eyelid Diseases MetaADEDB
Face Oedema ADReCS
Facial Dermatoses MetaADEDB
Factor V Deficiency MetaADEDB
Fasting ADReCS
Fat Tissue Increased MetaADEDB
Fatigue MetaADEDB
Fear Of Death MetaADEDB
Febrile Neutropenia MetaADEDB
Feeling Abnormal ADReCS
Feeling Hot ADReCS
Fibrosis MetaADEDB
Fibrous Histiocytoma MetaADEDB
Flatulence ADReCS
Flushing ADReCS
Foot Pain SIDER
Gall Bladder MetaADEDB
Gastrointestinal Pain ADReCS
Gingival Hyperplasia ADReCS
Globulinuria MetaADEDB
Glomerulonephritis MetaADEDB
Glomerulonephritis Membranous ADReCS
Gout MetaADEDB
Granulocytosis MetaADEDB
Gynaecomastia ADReCS
Haematoma MetaADEDB
Haemorrhage Intracranial MetaADEDB
Hallucination Tactile MetaADEDB
Headache ADReCS
Heart Failure MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Failure MetaADEDB
Hepatitis ADReCS
Hepatitis Cholestatic ADReCS
Hernia MetaADEDB
Hernia Inguinal MetaADEDB
Herpes Zoster MetaADEDB
High Density Lipoprotein Decreased MetaADEDB
Hodgkin Disease MetaADEDB
Humerus Fracture MetaADEDB
Hyperemia MetaADEDB
Hyperhomocysteinaemia MetaADEDB
Hyperlipaemia MetaADEDB
Hyperparathyroidism Secondary MetaADEDB
Hyperplasia ADReCS
Hypertension MetaADEDB
Hypertension Renovascular MetaADEDB
Hypertensive Emergency MetaADEDB
Hypertrophy ADReCS
Hypertrophy Left Ventricular MetaADEDB
Hypoaesthesia MetaADEDB
Hypotension ADReCS
Hypothyroid MetaADEDB
Hypovolaemia MetaADEDB
Ild MetaADEDB
Iliac Artery Stenosis MetaADEDB
Ill-Defined Disorder ADReCS
Immunosuppressant Drug Level MetaADEDB
Impingement Syndrome MetaADEDB
Impotence ADReCS
Inappropriate Schedule Of Drug Administration MetaADEDB
Infarction ADReCS
Infection ADReCS
Infection Urinary Tract MetaADEDB
Infection Viral MetaADEDB
Influenza ADReCS
Influenza Like Illness ADReCS
Insomnia ADReCS
Intention Tremor MetaADEDB
Internal Fixation Of Fracture MetaADEDB
International Normalised Ratio Decreased MetaADEDB
International Normalised Ratio Increased MetaADEDB
Interstitial Nephritis MetaADEDB
Intervertebral Disc Degeneration MetaADEDB
Irritability ADReCS
Joint Range Of Motion Decreased MetaADEDB
Kidney Failure MetaADEDB
Knee Pain SIDER
Laceration MetaADEDB
Leg Pain ADReCS
Leukocytoclastic Vasculitis ADReCS
Leukocyturia MetaADEDB
Libido Decreased ADReCS
Lichenification MetaADEDB
Limb Injury MetaADEDB
Liver Operation MetaADEDB
Loss Of Consciousness ADReCS
Lung Fibrosis MetaADEDB
Lung Infection MetaADEDB
Lung Neoplasm Malignant MetaADEDB
Lymphedema MetaADEDB
Lymphocele MetaADEDB
Lymphoma MetaADEDB
Lymphorrhoea MetaADEDB
Malaise ADReCS
Malignant Hypertension MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Mastectomy MetaADEDB
Metastases To Lymph Nodes MetaADEDB
Microangiopathic Haemolytic Anaemia MetaADEDB
Micturition Urgency ADReCS
Mineral Metabolism Disorder MetaADEDB
Mitral Valve Sclerosis MetaADEDB
Motor Dysfunction MetaADEDB
Multiple Drug Overdose MetaADEDB
Muscle Disorder MetaADEDB
Muscle Inflammation MetaADEDB
Muscle Spasms ADReCS
Muscle Weakness MetaADEDB
Musculoskeletal Discomfort ADReCS
Musculoskeletal Stiffness MetaADEDB
Myalgia ADReCS
Myocardial Infarction ADReCS
Nasal Cyst MetaADEDB
Nasopharyngitis ADReCS
Nausea ADReCS
Near Syncope MetaADEDB
Nephrogenic Fibrosing Dermopathy MetaADEDB
Nephrolithiasis MetaADEDB
Nervousness ADReCS
Neutropenic Infection MetaADEDB
Neutropenic Sepsis MetaADEDB
Nocturia MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Oliguria MetaADEDB
Opportunistic Infection MetaADEDB
Orthostatic Hypotension ADReCS
Osteopenia MetaADEDB
Pain ADReCS
Pain In Arm ADReCS
Pain In Extremity ADReCS
Palpitations ADReCS
Paraesthesia ADReCS
Parasomnia MetaADEDB
Peau DOrange MetaADEDB
Pedal Pulse Absent MetaADEDB
Peritonitis MetaADEDB
Peroneal Nerve Palsy MetaADEDB
Pharyngitis ADReCS
Phlebolith MetaADEDB
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Pigmentation Disorder MetaADEDB
Pneumonia Mycoplasmal MetaADEDB
Pneumonia Viral MetaADEDB
Pollakiuria ADReCS
Polyomavirus-Associated Nephropathy MetaADEDB
Polyuria ADReCS
Post Herpetic Neuralgia MetaADEDB
Poverty MetaADEDB
Prothrombin Time MetaADEDB
Pruritus ADReCS
Pulmonary Function Test Decreased MetaADEDB
Pulmonary Mass MetaADEDB
Radiotherapy MetaADEDB
Rash ADReCS
Rectal Examination Abnormal MetaADEDB
Regurgitation ADReCS
Renal Artery Stenosis MetaADEDB
Renal Atrophy MetaADEDB
Renal Cyst MetaADEDB
Renal Tubular Necrosis MetaADEDB
Respiratory Failure MetaADEDB
Respiratory Gas Exchange Disorder MetaADEDB
Respiratory Tract Infection ADReCS
Retinal Artery Occlusion MetaADEDB
Retinal Cyst MetaADEDB
Rhabdomyolysis MetaADEDB
Rhinorrhea MetaADEDB
Rhinorrhoea ADReCS
Rib Fracture MetaADEDB
Salivary Gland Enlargement ADReCS
Scratch MetaADEDB
Seizures MetaADEDB
Sexual Dysfunction ADReCS
Shock ADReCS
Sickness SIDER
Sinus Antrostomy MetaADEDB
Sinusitis ADReCS
Skin Discolouration MetaADEDB
Skin Fibrosis MetaADEDB
Skin Hypertrophy MetaADEDB
Skin Induration MetaADEDB
Skin Laceration MetaADEDB
Skin Tightness MetaADEDB
Sleep Inertia MetaADEDB
Sneezing ADReCS
Somnolence ADReCS
Spinal Compression Fracture MetaADEDB
Spinal Cord Infarction MetaADEDB
Spinning Sensation MetaADEDB
Spondylolisthesis MetaADEDB
Staring MetaADEDB
Steal Syndrome MetaADEDB
Syncope ADReCS
Synovial Cyst MetaADEDB
Tachycardia ADReCS
Tachycardia Sinus MetaADEDB
Telangiectasis MetaADEDB
Tension ADReCS
Tension Headache MetaADEDB
Tongue Paralysis MetaADEDB
Transient Ischaemic Attack MetaADEDB
Treatment Failure MetaADEDB
Tremor ADReCS
Ulcer MetaADEDB
Upper Respiratory Tract Infection ADReCS
Urate SIDER
Urinary Tract Inflammation MetaADEDB
Urine Output Increased ADReCS
Urticaria ADReCS
Vascular Pseudoaneurysm MetaADEDB
Vasculitis ADReCS
Ventricular Hypokinesia MetaADEDB
Vertebral Injury MetaADEDB
Visual Disturbance ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Wheeze MetaADEDB
Wrong Technique In Drug Usage Process MetaADEDB

InAADR: Drug-Protein-ADRs database