InAADR

Drug Information

Drug Name: S-mephenytoin (70989-04-7)
PubChem ID: 107921
SMILES: CC[C@@]1(C(=O)N(C(=O)N1)C)C2=CC=CC=C2
InchiKey: GMHKMTDVRCWUDX-LBPRGKRZSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 218.256
LogP: 1.4735
Ring Count: 1
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 49.41

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Dangerous Side Effects Cytochrome P450 2B6 (P20813) Estradiol inhibits CYP2B6 activity@ as a result it increases the level of mephenytoin in blood and causes dangerous side effects [ ADR Type 4 ] Oxidation of quinidine by human liver cytochrome P-450
Dangerous Side Effects Cytochrome P450 2C19 (P33261) Ethosuximide inhibits CYP2C19-mediated S-mephenytoin 4#-hydroxylation@ which may increase the level of mephenytoin in blood and cause dangerous side effects. [ ADR Type 4 ] Safety of anticonvulsants in hepatic porphyrias

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source

InAADR: Drug-Protein-ADRs database