| Drug Name: | Furazolidone (67-45-8) |
|---|---|
| PubChem ID: | 5323714 |
| SMILES: | C1COC(=O)N1/N=C/C2=CC=C(O2)[N+](=O)[O-] |
| InchiKey: | PLHJDBGFXBMTGZ-WEVVVXLNSA-N |
| Therapeutic Category: | Anti-Infective Agents, Antiparasitic Agents, Antiprotozoal Agents, Antitrichomonal Agents, Enzyme Inhibitors, Monoamine Oxidase Inhibitors, Renal Agents |
| Molecular Weight (dalton) | : | 225.16 |
| LogP | : | 0.9739 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 6 |
| Hydrogen Bond Donor Count | : | 0 |
| Total Polar Surface Area | : | 98.18 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Amphetamine (300-62-9) | Rise In Blood Pressure | Antagonistic | Amphetamine interacts with furazolidone gradually after 5 to 10 days of use | The anti-monoamine oxidase effects of furazolidone |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Loss Of Appetite | Alanine aminotransferase (P24298) | Increase in serum aspartate aminotransferase (AST)@ Alanine aminotransferase (ALT) and alkaline phosphatase and a decrease in serum total protein@which leads to a loss of appetite causing emaciation followed by nervous disturbances (compulsive movements and circling) [ ADR Type 1 ] | Toxicological and biological studies on Japanese quails fed graded levels of furazolidone |
| Loss Of Appetite | Alkaline phosphatase (P05186) | Increase in serum aspartate aminotransferase (AST)@ Alanine aminotransferase (ALT) and alkaline phosphatase and a decrease in serum total protein@which leads to a loss of appetite causing emaciation followed by nervous disturbances (compulsive movements and circling). [ ADR Type 1 ] | Toxicological and biological studies on Japanese quails fed graded levels of furazolidone |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category