InAADR

Drug Information

Drug Name: Bisoprolol (66722-44-9)
PubChem ID: 2405
SMILES: CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O
InchiKey: VHYCDWMUTMEGQY-UHFFFAOYSA-N
Therapeutic Category: Adrenergic Agents, Adrenergic Antagonists, Adrenergic beta-1 Receptor Antagonists, Adrenergic beta-Antagonists, Antihypertensive Agents, Autonomic Agents, Cardiovascular Agents, Neurotransmitter Agents, Peripheral Nervous System Agents, Sympatholytics

Computed Drug Properties

Molecular Weight (dalton): 325.449
LogP: 2.3659
Ring Count: 1
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 59.95

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Increased Beta-Blockade CYP2D6 (P10635) Increased beta-blockade [ ADR Type 1 ] Drugs in special patient groups: clinical importance of genomics in drug effects In: Carruthers GS, Hoffmann BB,Melmon KL, Nierenberg DW

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain SIDER
Abdominal Pain ADReCS
Abnormal Dreams ADReCS
Abscess Bacterial MetaADEDB
Abscess Intestinal MetaADEDB
Accelerated Hypertension MetaADEDB
Ache SIDER
Aching Muscles MetaADEDB
Acne ADReCS
Acute Coronary Syndrome ADReCS
Acute Kidney Injury MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adynamic Ileus MetaADEDB
Affect Lability ADReCS
Afib MetaADEDB
Ageusia ADReCS
Agitation ADReCS
Agranulocytoses MetaADEDB
Agranulocytosis ADReCS
Alanine Aminotransferase Increased ADReCS
Alopecia ADReCS
Alveolitis MetaADEDB
Amentia MetaADEDB
Anaemia MetaADEDB
Angina MetaADEDB
Angina Pectoris MetaADEDB
Angioedema ADReCS
Angioplasty MetaADEDB
Anosmia ADReCS
Anticonvulsant Drug Level Increased MetaADEDB
Antinuclear Antibody MetaADEDB
Anxiety ADReCS
Aortic Stenosis MetaADEDB
Aphasia ADReCS
Aphthous Stomatitis MetaADEDB
Apoplexy MetaADEDB
Application Site Vesicles MetaADEDB
Arrhythmia ADReCS
Arterial Disorder MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arterial Stenosis MetaADEDB
Arterial Thrombosis ADReCS
Arterial Thrombosis Limb MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arthralgia ADReCS
Arthropathy MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Asphyxia MetaADEDB
Asthenia ADReCS
Asthma ADReCS
Asystole MetaADEDB
Atrial Fibrillation ADReCS
Atrial Thrombosis MetaADEDB
Atrioventricular Block SIDER
Atrioventricular Block Second Degree MetaADEDB
Atrophy MetaADEDB
Back Pain ADReCS
Bacterial Toxaemia MetaADEDB
Balance Disorder ADReCS
Bedridden MetaADEDB
Belching MetaADEDB
Benign Tumour Excision MetaADEDB
Bile Duct Obstruction MetaADEDB
Biliary Cirrhosis MetaADEDB
Biliary Tract Disorder MetaADEDB
Bilirubin Conjugated Abnormal MetaADEDB
Bladder Cancer MetaADEDB
Bladder Inflammation MetaADEDB
Bladder Pain ADReCS
Bleeding Gums MetaADEDB
Blindness ADReCS
Blood Creatine Increased ADReCS
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Glucose Increased ADReCS
Blood Phosphorus Increased ADReCS
Blood Potassium Increased ADReCS
Blood Pressure Systolic Decreased MetaADEDB
Blood Sodium MetaADEDB
Blood Triglycerides Increased ADReCS
Blood Urea Increased ADReCS
Blood Uric Acid Increased ADReCS
Body Temperature Increased ADReCS
Bone Inflammation MetaADEDB
Bone Pain MetaADEDB
Bradycardia ADReCS
Brain Stem Infarction MetaADEDB
Breast Pain ADReCS
Bronchitis ADReCS
Bronchoalveolar Lavage Abnormal MetaADEDB
Bronchospasm ADReCS
Bundle Branch Block MetaADEDB
Burn Oesophageal MetaADEDB
Burning Sensation Mucosal MetaADEDB
Carbon Monoxide Diffusing Capacity Decreased MetaADEDB
Cardiac Arrest ADReCS
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Failure ADReCS
Cardiac Failure Congestive ADReCS
Cardiac Fibrillation ADReCS
Cardiac Ischemia MetaADEDB
Cardiac Valve Disease MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiomyopathies MetaADEDB
Catatonia ADReCS
Cerebral Infarct MetaADEDB
Chest Pain ADReCS
Choking Sensation MetaADEDB
Cholelithotomy MetaADEDB
Cholesterosis MetaADEDB
Chronic Left Ventricular Failure MetaADEDB
Claudication SIDER
Clostridial Infection MetaADEDB
Cold Extremities ADReCS
Colitis ADReCS
Colitis Ischaemic ADReCS
Colitis Pseudomembranous MetaADEDB
Coma ADReCS
Concomitant Disease Aggravated MetaADEDB
Concomitant Disease Progression MetaADEDB
Confusional State ADReCS
Congenital Eye Disorder SIDER
Congenital Mitral Valve Incompetence MetaADEDB
Congenital Poikiloderma MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Conjunctivitis ADReCS
Constipation ADReCS
Contraindication To Medical Treatment MetaADEDB
Convulsions Grand Mal MetaADEDB
Corneal Abscess MetaADEDB
Corneal Oedema MetaADEDB
Coronary Artery Stenosis MetaADEDB
Cough ADReCS
Cramp Muscle SIDER
Crocodile Tears Syndrome ADReCS
Csf Monocyte Count Increased MetaADEDB
Cutaneous Vasculitis ADReCS
Cystitis ADReCS
Cystitis Noninfective ADReCS
Deafness ADReCS
Deafness Neurosensory MetaADEDB
Deafness Unilateral MetaADEDB
Death ADReCS
Death Sudden Cardiac MetaADEDB
Deglutition Disorder MetaADEDB
Depressed Level Of Consciousness ADReCS
Depression ADReCS
Dermatitis ADReCS
Dermatitis Exfoliative ADReCS
Dialysis MetaADEDB
Diarrhea MetaADEDB
Diarrhea Infectious MetaADEDB
Diarrhoea ADReCS
Discomfort ADReCS
Disorientation ADReCS
Disturbance In Attention ADReCS
Disturbance In Sexual Arousal ADReCS
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drowsiness SIDER
Drug Interaction MetaADEDB
Dry Eye MetaADEDB
Dry Mouth ADReCS
Dry Skin MetaADEDB
Dysgeusia ADReCS
Dyspepsia ADReCS
Dyspnea MetaADEDB
Dyspnoea ADReCS
Dyspnoea Exertional ADReCS
Ear Pain ADReCS
Eczema ADReCS
Ejection Fraction Decreased MetaADEDB
Electrocardiogram St Segment Depression MetaADEDB
Embolism ADReCS
Empyema MetaADEDB
Encephalopathy ADReCS
Enuresis MetaADEDB
Eosinophil Count Decreased MetaADEDB
Epistaxis MetaADEDB
Erectile Dysfunction ADReCS
Erysipelas MetaADEDB
Erythema ADReCS
Extrasystoles ADReCS
Extremity Necrosis MetaADEDB
Eye Disorder SIDER
Eye Pain ADReCS
Faecaloma MetaADEDB
Fatigue ADReCS
Feeding Tube Insertion MetaADEDB
Feeling Abnormal ADReCS
Flatulence MetaADEDB
Fluid Overload MetaADEDB
Fluid Retention ADReCS
Flushing ADReCS
Galactorrhoea ADReCS
Gangrene MetaADEDB
Gastric Disorder MetaADEDB
Gastritis ADReCS
Gastroduodenitis MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Injury MetaADEDB
Gastrointestinal Necrosis MetaADEDB
Gastrointestinal Pain ADReCS
General Physical Health Deterioration MetaADEDB
Generalised Oedema ADReCS
Glomerulonephritis Minimal Lesion MetaADEDB
Gout ADReCS
Granulocyte Count Decreased MetaADEDB
Haematoma MetaADEDB
Haemodynamic Instability MetaADEDB
Hallucination ADReCS
Headache ADReCS
Hearing Impaired ADReCS
Heart Attack MetaADEDB
Heart Failure MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Heparin-Induced Thrombocytopenia MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Failure MetaADEDB
Hepatitis MetaADEDB
Hepatocellular Damage MetaADEDB
Hot Flush ADReCS
Hyperaesthesia ADReCS
Hyperhidrosis ADReCS
Hypersensitivity ADReCS
Hypertension MetaADEDB
Hypoacusis ADReCS
Hypoaesthesia ADReCS
Hypoalbuminaemia MetaADEDB
Hypoglycaemia ADReCS
Hypokalemia MetaADEDB
Hypoproteinaemia MetaADEDB
Hypotension ADReCS
Hypoxia MetaADEDB
Idiopathic Thrombocytopenic Purpura MetaADEDB
Ild MetaADEDB
Ileal Ulcer MetaADEDB
Ill-Defined Disorder ADReCS
Immunosuppressant Drug Level MetaADEDB
Incorrect Drug Administration Duration MetaADEDB
Infarction ADReCS
Infection ADReCS
Insomnia ADReCS
Intermittent Claudication ADReCS
Internal Fixation Of Fracture MetaADEDB
International Normalised Ratio Decreased MetaADEDB
International Normalised Ratio Increased MetaADEDB
Intestinal Fistula MetaADEDB
Intestinal Mucosal Hypertrophy MetaADEDB
Intestinal Perforation MetaADEDB
Intracranial Venous Sinus Thrombosis MetaADEDB
Iris Cyst MetaADEDB
Iritis MetaADEDB
Ischaemia ADReCS
Ischaemic Cardiomyopathy MetaADEDB
Ischaemic Stroke MetaADEDB
Ischemia MetaADEDB
Ischemic Attack Transient MetaADEDB
Kidney Failure MetaADEDB
Klebsiella Sepsis MetaADEDB
Lacrimal Disorder ADReCS
Lacrimation SIDER
Lacrimation Increased ADReCS
Lacunar Infarction MetaADEDB
Laryngospasm ADReCS
Left Ventricular Failure ADReCS
Leukoaraiosis MetaADEDB
Libido Decreased ADReCS
Lichenoid Keratosis MetaADEDB
Lividity MetaADEDB
Long Qt Syndrome MetaADEDB
Loose Tooth MetaADEDB
Loss Of Consciousness ADReCS
Lung Abscess MetaADEDB
Lung Adenocarcinoma MetaADEDB
Malaise ADReCS
Meningioma MetaADEDB
Menopausal Symptoms ADReCS
Mesenteric Artery Thrombosis ADReCS
Metastases To Pleura MetaADEDB
Metastatic Neoplasm MetaADEDB
Migraine Disorders MetaADEDB
Mood Swings ADReCS
Mouth Bleeding MetaADEDB
Multifocal Leukoencephalopathy MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Muscle Fibrosis MetaADEDB
Muscle Inflammation MetaADEDB
Muscle Spasms ADReCS
Muscle Twitching ADReCS
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Myocardial Infarction ADReCS
Myopericarditis MetaADEDB
Nausea ADReCS
Neck Pain ADReCS
Necrolysis Epidermal SIDER
Nephrotic Syndrome MetaADEDB
Neumonia MetaADEDB
Neuralgia ADReCS
Nightmare ADReCS
Non-Cardiac Chest Pain MetaADEDB
Oculomucocutaneous Syndrome ADReCS
Oedema ADReCS
Oedema Peripheral ADReCS
Off Label Use MetaADEDB
Operative Haemorrhage MetaADEDB
Optic Disc Edema MetaADEDB
Optic Neuropathy MetaADEDB
Oropharyngeal Discomfort ADReCS
Oropharyngeal Pain ADReCS
Orthopnea MetaADEDB
Orthostatic Hypotension ADReCS
Osteolysis MetaADEDB
Overdose Effect SIDER
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Pain Pelvic MetaADEDB
Pallor MetaADEDB
Palpitations ADReCS
Pancreatic Carcinoma Metastatic MetaADEDB
Paraesthesia ADReCS
Paresis ADReCS
Peptic Ulcer ADReCS
Pericardial Effusion MetaADEDB
Peripheral Coldness ADReCS
Peripheral Ischaemia ADReCS
Peripheral Vascular Diseases MetaADEDB
Peritonitis MetaADEDB
Petechia MetaADEDB
Peyronie Disease ADReCS
Pharyngitis ADReCS
Phlebothrombosis MetaADEDB
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Platelet Count MetaADEDB
Platelet Count Decreased ADReCS
Pneumatosis MetaADEDB
Pneumocystis Jiroveci Pneumonia MetaADEDB
Pneumonia ADReCS
Pneumonia Streptococcal MetaADEDB
Polymyalgia Rheumatica MetaADEDB
Polyneuropathy In Malignant Disease MetaADEDB
Polyuria ADReCS
Post Procedural Haemorrhage MetaADEDB
Postural Orthostatic Tachycardia Syndrome MetaADEDB
Pruritus ADReCS
Psoriasis ADReCS
Pulmonary Hypertension MetaADEDB
Pulmonary Oedema ADReCS
Purpura ADReCS
Pyrexia ADReCS
Quadriplegia MetaADEDB
Radius Fracture MetaADEDB
Rales MetaADEDB
Rash ADReCS
Raynaud Disease SIDER
Raynaud Phenomenon SIDER
Renal Colic ADReCS
Respiratory Disorder MetaADEDB
Respiratory Distress ADReCS
Respiratory Failure ADReCS
Respiratory Insufficiency SIDER
Reticulocytosis MetaADEDB
Retinal Artery Occlusion MetaADEDB
Retinal Pigment Epithelial Tear MetaADEDB
Rhabdomyolysis MetaADEDB
Rhinitis ADReCS
Ruptured Cerebral Aneurysm MetaADEDB
Scleroderma ADReCS
Scotoma MetaADEDB
Scratch MetaADEDB
Sepsis Syndrome MetaADEDB
Septic Shock MetaADEDB
Serum Triglycerides Increased SIDER
Shock ADReCS
Sickness SIDER
Sinusitis ADReCS
Skin Discolouration ADReCS
Skin Hyperpigmentation ADReCS
Skin Irritation ADReCS
Sleep Apnea MetaADEDB
Sleep Disorder ADReCS
Sleep Disorders MetaADEDB
Sleep Disturbance SIDER
Somnolence ADReCS
Speech Disorder ADReCS
Spinal Cord Compression MetaADEDB
Spinning Sensation MetaADEDB
Spondylolysis MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Stent Placement MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Sweating SIDER
Sweating Increased SIDER
Syncope ADReCS
Tachycardia ADReCS
Taste Abnormality ADReCS
Temporospatial Disorientation ADReCS
Tenderness ADReCS
Thought Blocking MetaADEDB
Throat Sore SIDER
Thrombocytopenia ADReCS
Thrombocytopenic Purpura ADReCS
Thrombosis ADReCS
Tingling Sensation SIDER
Tinnitus ADReCS
Torsades De Pointes MetaADEDB
Toxic Epidermal Necrolysis ADReCS
Toxicity To Various Agents SIDER
Transaminases Increased MetaADEDB
Tremor ADReCS
Ulcer ADReCS
Unsteadiness SIDER
Upper Respiratory Tract Infection ADReCS
Upper Respiratory Tract Inflammation MetaADEDB
Urination Disorders MetaADEDB
Urine Albumin/Creatinine Ratio MetaADEDB
Urine Colour Abnormal MetaADEDB
Urine Output Increased ADReCS
Urticaria ADReCS
Vascular Purpura ADReCS
Vasculitis ADReCS
Venous Thrombosis Limb MetaADEDB
Ventricular Fibrillation ADReCS
Ventricular Premature Complexes MetaADEDB
Vertigo ADReCS
Visual Acuity Reduced ADReCS
Visual Disturbance ADReCS
Visual Impairment ADReCS
Vith Nerve Disorder MetaADEDB
Vivid Dreams SIDER
Vomiting ADReCS
Weight Decreased ADReCS
Weight Increased ADReCS
Wound MetaADEDB

InAADR: Drug-Protein-ADRs database