| Drug Name: | Ketorolac (66635-83-4) |
|---|---|
| PubChem ID: | 3826 |
| SMILES: | C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1C(=O)O |
| InchiKey: | OZWKMVRBQXNZKK-UHFFFAOYSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 255.273 |
| LogP | : | 2.291 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 3 |
| Hydrogen Bond Donor Count | : | 1 |
| Total Polar Surface Area | : | 59.3 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Probenecid (57-66-9) | Disorder Gastrointestinal | Antagonistic | Probenecid is a known substrate for renal glucuronidation, and possibly competitively inhibits the renal glucuronidation of these NSAIDs | Probenecid inhibits the glucuronidation of indomethacin and O-desmethylindomethacin in humans A pilot experiment |
| Vancomycin (1404-90-6) | Gastrointestinal Bleeding | Additive | Not Known | Acute renal failure and gastrointestinal bleed associated with postoperative toradol and vancomycin |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category