| Drug Name: | Dicumarol (66-76-2) |
|---|---|
| PubChem ID: | 54676038 |
| SMILES: | C1=CC=C2C(=C1)C(=C(C(=O)O2)CC3=C(C4=CC=CC=C4OC3=O)O)O |
| InchiKey: | DOBMPNYZJYQDGZ-UHFFFAOYSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 336.299 |
| LogP | : | 2.9014 |
| Ring Count | : | 4 |
| Hydrogen Bond Acceptor Count | : | 6 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 100.88 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Phenytoin (57-41-0) | Phenytoin Toxicity | Synergistic | Dicoumarol appear to inhibit the metabolism of phenytoin by the liver, so that its loss from the body is reduced. Phenytoin is an inducer of the cytochrome P450 isoenzyme CYP2C9, which is involved in metabolism of the coumarin anticoagulants | Dicoumarol-induced diphenylhydantoin intoxication |
| Stanozolol (10418-03-8) | Bleeding | Antagonistic | Not understood | Anabolic steroids and anticoagulants |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category