Drug Name: | Glucagon (64790-15-4) |
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PubChem ID: | 3080901 |
SMILES: | CC(C)CC(C(=O)NC(CCSC)C(=O)NC(CC(=O)N)C(=O)NC(C(C)O)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C(CCC(=O)N)NC(=O)C(C(C)C)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C(C)N |
InchiKey: | SVHJFTNFNMWDBS-FPLSMPAJSA-N |
Therapeutic Category: |
Molecular Weight (dalton) | : | 1352.53 |
LogP | : | -4.05 |
Ring Count | : | 3 |
Hydrogen Bond Acceptor Count | : | 18 |
Hydrogen Bond Donor Count | : | 18 |
Total Polar Surface Area | : | 556.91 |
This panel provides information on interacting drugs and their ADRs along with references
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This panel provides drug-protein interaction and their ADRs along with references
Toxicity | Interacting Protein | Mechanism | Reference |
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Cell Death | cAMP-dependent protein kinase (P17612) | Direct pharmacological evidence for the activation of the cAMP-dependent protein kinase in response to glucagon in the intact cell@which leads to cell death. [ ADR Type 2 ] | A study of the mechanism of glucagon-induced protein phosphorylation in isolated rat hepatocytes using (Sp)-cAMPS and (Rp)-cAMPS, the stimulatory and inhibitory diastereomers of adenosine cyclic 3',5'-phosphor |
This panel provides drug-food interactions and their ADRs along with references
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This panel provides information on metabolites and their ADRs along with references
Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category