| Drug Name: | Cefotaxime (63527-52-6) |
|---|---|
| PubChem ID: | 5742673 |
| SMILES: | CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=NOC)/C3=CSC(=N3)N)SC1)C(=O)O |
| InchiKey: | GPRBEKHLDVQUJE-QSWIMTSFSA-N |
| Therapeutic Category: | Anti-Bacterial Agents, Anti-Infective Agents |
| Molecular Weight (dalton) | : | 455.474 |
| LogP | : | -0.6225 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 11 |
| Hydrogen Bond Donor Count | : | 3 |
| Total Polar Surface Area | : | 173.51 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Azlocillin (37091-66-0) | Impaired Renal Function | Antagonistic | Not known | Influence of coadministration on the pharmacokinetics of mezlocillin and cefotaxime in healthy volunteers and in patients with renal failure |
| Mezlocillin (51481-65-3) | Impaired Renal Function | Antagonistic | Not known | Focal motor status epilepticus following treatment with azlocillin and cefotaxime |
| Phenobarbital (50-06-6) | Skin Reaction | Additive | Not known | Unerwünschte Arzneimittelreaktionen bei gleichzeitiger Gabe von hochdosiertem Phenobarbital und Betalaktam-Antibiotika |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category