| Drug Name: | Oxaliplatin (61825-94-3) |
|---|---|
| PubChem ID: | 5310940 |
| SMILES: | C1CCC(C(C1)N)N.C(=O)(C(=O)O)O.[Pt] |
| InchiKey: | OGAPHRMCCQCJOE-BNTLRKBRSA-N |
| Therapeutic Category: | Antineoplastic Agents |
| Molecular Weight (dalton) | : | 399.304 |
| LogP | : | -0.6319 |
| Ring Count | : | 0 |
| Hydrogen Bond Acceptor Count | : | 4 |
| Hydrogen Bond Donor Count | : | 4 |
| Total Polar Surface Area | : | 126.64 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Irinotecan (97682-44-5) | Abdominal Pain | Synergistic | the cholinergic effects of irinotecan, which is a potent inhibitor of acetylcholinesterase, may be enhanced by oxaliplatin | Irinotecan-related cholinergic syndrome induced by coadministration of oxaliplatin |
| Irinotecan (97682-44-5) | Hypersalivation | Synergistic | the cholinergic effects of irinotecan, which is a potent inhibitor of acetylcholinesterase, may be enhanced by oxaliplatin | Irinotecan-related cholinergic syndrome induced by coadministration of oxaliplatin |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category