| Drug Name: | Cefotiam (61622-34-2) |
|---|---|
| PubChem ID: | 43708 |
| SMILES: | CN(C)CCN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)CC4=CSC(=N4)N)SC2)C(=O)O |
| InchiKey: | QYQDKDWGWDOFFU-IUODEOHRSA-N |
| Therapeutic Category: | Anti-Bacterial Agents, Anti-Infective Agents |
| Molecular Weight (dalton) | : | 525.642 |
| LogP | : | -0.6532 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 13 |
| Hydrogen Bond Donor Count | : | 3 |
| Total Polar Surface Area | : | 172.46 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Acenocoumarol (152-72-7) | Anticoagulation | Additive | cephalosporins with the N-methylthiotetrazole side-chain appear to increase the risk of bleeding, and might therefore interact | Influence of cephalosporin antibiotics on blood coagulation and platelet function |
| Methotrexate (59-05-2) | Pancytopenia | Synergistic | Not understood | Pancytopenia and Colitis with Clostridium difficile in a Rheumatoid Arthritis Patient Taking Methotrexate, Antibiotics and Non-steroidal Anti-inflammatory Drugs |
| Warfarin (81-81-2) | Anticoagulation | Additive | cephalosporins with the N-methylthiotetrazole side-chain appear to increase the risk of bleeding, and might therefore interact | Influence of cephalosporin antibiotics on blood coagulation and platelet function |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category