InAADR: Drug-Protein-ADRs database

Drug Name:	Pronestyl (614-39-1)
PubChem ID:	66068
SMILES:	CCN(CC)CCNC(=O)C1=CC=C(C=C1)N.Cl
InchiKey:	ABTXGJFUQRCPNH-UHFFFAOYSA-N
Therapeutic Category:

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug	Toxicity	Interaction Type	Mechanism	Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity	Interacting Protein	Mechanism	Reference
Proarrhythmia	CYP2D6 (P10635)	Proarrhythmic and other toxic effects [ ADR Type 2 ]	Drugs in special patient groups: clinical importance of genomics in drug effects In: Carruthers GS, Hoffmann BB,Melmon KL, Nierenberg DW
Sudden Cardiac Death	Potassium voltage-gated channel subfamily E member 1 (P15382)	Sudden cardiac death due to long-QT syndrome [ ADR Type 2 ]	Genetic and molecular basis of cardiac arrhythmias: impact on clinical management parts I and II
Sudden Cardiac Death	Potassium voltage-gated channel subfamily H member 2 (Q12809)	Sudden cardiac death due to long-QT syndrome [ ADR Type 2 ]	Genetic and molecular basis of cardiac arrhythmias: impact on clinical management parts I and II
Sudden Cardiac Death	Potassium voltage-gated channel subfamily KQT member 1 (P51787)	Sudden cardiac death due to long-QT syndrome [ ADR Type 2 ]	Genetic and molecular basis of cardiac arrhythmias: impact on clinical management parts I and II
Sudden Cardiac Death	Sodium channel protein type 5 subunit alpha (Q14524)	Sudden cardiac death due to long-QT syndrome [ ADR Type 2 ]	Genetic and molecular basis of cardiac arrhythmias: impact on clinical management parts I and II

This panel provides drug-food interactions and their ADRs along with references

Food	Toxicity	Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite	Toxicity	Place of Metabolism	Mechanism	Reference

This panel provides information on drug category

Toxicity	Source

Molecular Weight (dalton)	:	271.792
LogP	:	1.7622
Ring Count	:	1
Hydrogen Bond Acceptor Count	:	3
Hydrogen Bond Donor Count	:	2
Total Polar Surface Area	:	58.36