InAADR

Drug Information

Drug Name: METHYLENE BLUE (61-73-4)
PubChem ID: 6099
SMILES: CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.[Cl-]
InchiKey: CXKWCBBOMKCUKX-UHFFFAOYSA-M
Therapeutic Category: Enzyme Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 319.861
LogP: -0.4971
Ring Count: 1
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 19.14

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Mucosal Damage And The Mpo Activity Tumor necrosis factor precursor (P01375) Methylene blue decreased TNF-alpha response to reperfusion injury but significantly increased the grade of the mucosal damage and the MPO activity. [ ADR Type 1 ] Effects of the anti-ICAM-1 monoclonal antibody, allopurinol, and methylene blue on intestinal reperfusion injury

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Sepsis MetaADEDB
Abnormal Vision MetaADEDB
Acidosis MetaADEDB
Acquired Methaemoglobinaemia MetaADEDB
Agitated MetaADEDB
Agnosia MetaADEDB
Agraphia MetaADEDB
Alkalosis MetaADEDB
Anticholinergic Syndrome MetaADEDB
Aphasia MetaADEDB
Arthropathy MetaADEDB
Ataxia MetaADEDB
Athetosis MetaADEDB
Atrial Tachycardia MetaADEDB
Binocular Eye Movement Disorder MetaADEDB
Black Stools MetaADEDB
Blindness Cortical MetaADEDB
Blood Calcium MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Culture Positive MetaADEDB
Blood Potassium Increased MetaADEDB
Blurred Vision MetaADEDB
Body Temperature Increased MetaADEDB
Brain Diseases MetaADEDB
Bundle Branch Block MetaADEDB
Bundle Branch Block Left MetaADEDB
Calcium Ionised MetaADEDB
Carcinoid Syndrome MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Output Decreased MetaADEDB
Cellulitis MetaADEDB
Central Nervous System Diseases MetaADEDB
Cerebral Disorder MetaADEDB
Chest Pain ADReCS
Chill MetaADEDB
Chromaturia MetaADEDB
Clonus MetaADEDB
Coma MetaADEDB
Communication Disorder MetaADEDB
Complications Of Transplanted Liver MetaADEDB
Confabulation MetaADEDB
Confusional State ADReCS
Cyanosis MetaADEDB
Demyelination MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitides MetaADEDB
Dermatosis MetaADEDB
Disinhibition MetaADEDB
Disorder Of Globe MetaADEDB
Dizziness ADReCS
Drug Interaction MetaADEDB
Drug Toxicity MetaADEDB
Dysgeusia MetaADEDB
Dystonia MetaADEDB
Electrocardiogram St Segment Depression MetaADEDB
Electrocardiogram St-T Segment Depression MetaADEDB
Emesis MetaADEDB
Emotional Distress MetaADEDB
Encephalopathy MetaADEDB
Excess Potassium MetaADEDB
Extrasystoles MetaADEDB
Feeling Abnormal ADReCS
General Physical Health Deterioration MetaADEDB
Glasgow Coma Scale MetaADEDB
Haematoma MetaADEDB
Haemodialysis MetaADEDB
Haemodynamic Instability MetaADEDB
Headache ADReCS
High Blood Pressure MetaADEDB
Hyperalgesia MetaADEDB
Hypercapnia MetaADEDB
Hyperemia MetaADEDB
Hyperhidrosis MetaADEDB
Hyperreflexia MetaADEDB
Hyperventilation MetaADEDB
Hypotension MetaADEDB
Immediate Post-Injection Reaction MetaADEDB
Incorrect Drug Administration Rate MetaADEDB
Infusion Related Reaction MetaADEDB
Inhibitory Drug Interaction MetaADEDB
Intention Tremor MetaADEDB
Laboratory Test Interference MetaADEDB
Laceration MetaADEDB
Learning Disorders MetaADEDB
Leukoencephalopathy MetaADEDB
Low Cardiac Output Syndrome MetaADEDB
Lung Edema MetaADEDB
Memory Disorders MetaADEDB
Methaemoglobinaemia MetaADEDB
Methemoglobinemia MetaADEDB
Multi-Organ Failure MetaADEDB
Muscle Inflammation MetaADEDB
Nausea ADReCS
Nystagmus MetaADEDB
Oculogyric Crisis MetaADEDB
Optic Nerve Diseases MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Panic Disorder MetaADEDB
Parathyroid Tumour Benign MetaADEDB
Pco2 Increased MetaADEDB
Penile Diseases MetaADEDB
Photosensitive Rash MetaADEDB
Po2 Decreased MetaADEDB
Post Procedural Complication MetaADEDB
Priapism MetaADEDB
Pupillary Reflex Impaired MetaADEDB
Retinal Degeneration MetaADEDB
Sclerosing Encapsulating Peritonitis MetaADEDB
Skin Discolouration MetaADEDB
Skin Lesion MetaADEDB
Small Intestinal Haemorrhage MetaADEDB
Speech Disorder MetaADEDB
Staring MetaADEDB
Status Epilepticus MetaADEDB
Sudden Death MetaADEDB
Tauopathies MetaADEDB
Toxic Encephalopathy MetaADEDB
Vasoplegia MetaADEDB
Vision Disorders MetaADEDB

InAADR: Drug-Protein-ADRs database