InAADR

Drug Information

Drug Name: Vigabatrin (60643-86-9)
PubChem ID: 5665
SMILES: C=CC(CCC(=O)O)N
InchiKey: PJDFLNIOAUIZSL-UHFFFAOYSA-N
Therapeutic Category: Anticonvulsants, Central Nervous System Agents, Enzyme Inhibitors, GABA Agents, Neurotransmitter Agents

Computed Drug Properties

Molecular Weight (dalton): 129.159
LogP: 0.3645
Ring Count: 0
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 63.32

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference
Phenytoin (57-41-0) Increase In Seizure Frequency Antagonistic Not understood A multicentre study of vigabatrin for drug-resistant epilepsy

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abdominal Wall Cyst MetaADEDB
Abnormal Behaviour ADReCS
Abnormal Dreams ADReCS
Accidental Overdose MetaADEDB
Acute Psychosis ADReCS
Adh Inappropriate MetaADEDB
Affect Lability ADReCS
Aggression ADReCS
Aggressive Reaction SIDER
Agitated MetaADEDB
Agitation ADReCS
Agitation Neonatal ADReCS
Alcohol-Induced Disorders MetaADEDB
Alexander Disease MetaADEDB
Altered State Of Consciousness ADReCS
Alveolitis MetaADEDB
Amino Acid Level Increased MetaADEDB
Amnesia ADReCS
Amphetamine-Related Disorders MetaADEDB
Anal Atresia MetaADEDB
Angioedema ADReCS
Anhidrosis MetaADEDB
Anomaly Of External Ear Congenital ADReCS
Antidepressant Drug Clearance Increased MetaADEDB
Anxiety ADReCS
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Apathy ADReCS
Aplasia ADReCS
Arrested Labour MetaADEDB
Arthralgia ADReCS
Arthrogram MetaADEDB
Arthropathy ADReCS
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Asthenopia ADReCS
Ataxia ADReCS
Atrial Septal Defect MetaADEDB
Atrophy ADReCS
Back Pain ADReCS
Bacterial Toxaemia MetaADEDB
Basal Ganglia Diseases MetaADEDB
Binocular Eye Movement Disorder MetaADEDB
Bipolar Disorder MetaADEDB
Bleb MetaADEDB
Blepharospasm MetaADEDB
Blindness ADReCS
Blood Glucose Decreased MetaADEDB
Blood Ph Increased MetaADEDB
Body Dysmorphic Disorder MetaADEDB
Body Temperature Increased ADReCS
Bone Marrow Disorder MetaADEDB
Bradycardia MetaADEDB
Brain Diseases MetaADEDB
Brain Injuries MetaADEDB
Bronchitis ADReCS
Candidiasis ADReCS
Cardiac Septal Defect MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebral Dysgenesis MetaADEDB
Cerebral Palsy MetaADEDB
Cerebral Ventricle Dilatation MetaADEDB
Cerebration Impaired SIDER
Chest Pain ADReCS
Choking Sensation MetaADEDB
Cholecystitis MetaADEDB
Cholestasis ADReCS
Clonus MetaADEDB
Clotting MetaADEDB
Coagulation Factor Xiii Level Decreased MetaADEDB
Cocaine-Related Disorders MetaADEDB
Cold Sweat MetaADEDB
Color Vision Defects MetaADEDB
Coma MetaADEDB
Communication Disorder MetaADEDB
Completed Suicide ADReCS
Concomitant Disease Progression MetaADEDB
Condition Aggravated MetaADEDB
Confusional State ADReCS
Congenital Anomaly ADReCS
Congenital Flat Feet MetaADEDB
Congenital Genital Malformation ADReCS
Congenital Genital Malformation Male ADReCS
Congenital Heart Disease MetaADEDB
Congenital Hydronephrosis ADReCS
Congenital Nose Malformation MetaADEDB
Congenital Oral Malformation ADReCS
Congenital Vesicoureteric Reflux ADReCS
Conjunctivitis ADReCS
Constipation ADReCS
Contusion ADReCS
Convulsion ADReCS
Coordination Abnormal ADReCS
Cough ADReCS
Croup SIDER
Croup Infectious ADReCS
Crying MetaADEDB
Crystal Urine MetaADEDB
Deafness ADReCS
Deafness Congenital MetaADEDB
Death MetaADEDB
Decreased Appetite ADReCS
Delayed Puberty ADReCS
Delirium ADReCS
Demyelinating Diseases MetaADEDB
Dentofacial Anomaly ADReCS
Depressed Level Of Consciousness ADReCS
Depressed Mood ADReCS
Depression ADReCS
Depressive Disorder MetaADEDB
Dermatitis ADReCS
Developmental Coordination Disorder ADReCS
Developmental Delay ADReCS
Device Occlusion MetaADEDB
Diarrhoea ADReCS
Diplopia ADReCS
Discomfort ADReCS
Disease Models Animal MetaADEDB
Dislocation MetaADEDB
Disorder Retinal MetaADEDB
Disorders Of Excessive Somnolence MetaADEDB
Disseminated Lupus Erythematosus MetaADEDB
Disturbance In Attention ADReCS
Dizziness ADReCS
Drowsiness SIDER
Drug Ineffective MetaADEDB
Drug Prescribing Error MetaADEDB
Drug Resistance MetaADEDB
Dysarthria ADReCS
Dysgraphia MetaADEDB
Dyskinesias MetaADEDB
Dysmenorrhoea ADReCS
Dysmorphism ADReCS
Dyspepsia ADReCS
Dysphemia MetaADEDB
Dysplasia ADReCS
Dyspnoea ADReCS
Dystonia ADReCS
Ear Disorder ADReCS
Ear Infection ADReCS
Ear Malformation ADReCS
Ear Pain ADReCS
Electroencephalogram Abnormal ADReCS
Embolism ADReCS
Encephalitis Allergic MetaADEDB
Encephalopathy ADReCS
Enzyme Abnormality MetaADEDB
Epilepsies Partial MetaADEDB
Epilepsy MetaADEDB
Epilepsy Absence MetaADEDB
Epilepsy Complex Partial MetaADEDB
Epilepsy Temporal Lobe MetaADEDB
Epiphysiolysis MetaADEDB
Erectile Dysfunction ADReCS
Excessive Thirst MetaADEDB
Expressive Language Disorder ADReCS
External Ear Disorder ADReCS
Eye Diseases MetaADEDB
Eye Disorder ADReCS
Eye Pain ADReCS
Eyelid Irritation MetaADEDB
Face Oedema ADReCS
Facial Dysmorphism MetaADEDB
Facial Palsy MetaADEDB
Faecaloma MetaADEDB
Fatigue ADReCS
Feeding Disorder MetaADEDB
Feeding Disorder Neonatal MetaADEDB
Feeling Abnormal ADReCS
Femur Fracture MetaADEDB
Flat Affect ADReCS
Fluid Retention ADReCS
Foetal Anticonvulsant Syndrome ADReCS
Foetal Distress Syndrome MetaADEDB
Foetal Valproate Syndrome MetaADEDB
Forgetfulness SIDER
Fracture Reduction MetaADEDB
Gait Disturbance ADReCS
Gastric Disorder ADReCS
Gastroenteritis ADReCS
Gastroenteritis Viral ADReCS
Gastrointestinal Disorder SIDER
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Pain ADReCS
Gastrooesophageal Reflux Disease ADReCS
Gestational Diabetes MetaADEDB
Gingival Hypertrophy MetaADEDB
Haemangioma ADReCS
Haemangioma Congenital ADReCS
Haematoma MetaADEDB
Haemoglobin ADReCS
Haemorrhage ADReCS
Haemorrhoids ADReCS
Hallucination ADReCS
Hamartoma ADReCS
Hamartoma Vascular ADReCS
Head Deformity MetaADEDB
Headache ADReCS
Hearing Loss Bilateral MetaADEDB
Hearing Loss Sensorineural MetaADEDB
Heart Disease Congenital ADReCS
Hernia MetaADEDB
Heroin Dependence MetaADEDB
Hip Dysplasia ADReCS
Hip Surgery MetaADEDB
Hydrocele MetaADEDB
Hydronephrosis ADReCS
Hyperkinesia ADReCS
Hyperreflexia ADReCS
Hypersensitivity ADReCS
Hyperthermia ADReCS
Hyperthermia Malignant ADReCS
Hypertonia ADReCS
Hypoaesthesia ADReCS
Hypomania ADReCS
Hyporeflexia ADReCS
Hypospadias MetaADEDB
Hypothermia MetaADEDB
Hypotonia ADReCS
Hypotonia Neonatal MetaADEDB
Ill-Defined Disorder ADReCS
Illiteracy MetaADEDB
Increased Appetite ADReCS
Infantile Spitting Up MetaADEDB
Infection ADReCS
Influenza ADReCS
Insomnia ADReCS
Irritability ADReCS
Ischemia MetaADEDB
Joint Contracture MetaADEDB
Joint Injury MetaADEDB
Joint Swelling ADReCS
Kyphoscoliosis MetaADEDB
Laryngeal Disorder MetaADEDB
Laryngeal Oedema ADReCS
Laryngomalacia MetaADEDB
Learning Disorder MetaADEDB
Lethargy ADReCS
Leukoencephalopathies MetaADEDB
Limb Malformation ADReCS
Limb Reduction Defect ADReCS
Lissencephaly MetaADEDB
Low Set Ears ADReCS
Maculopathy ADReCS
Malaise ADReCS
Malformations Of Cortical Development MetaADEDB
Mania ADReCS
Memory Impairment ADReCS
Menstrual Disorder ADReCS
Mental Disability ADReCS
Mental Disorder SIDER
Metabolic Disorder MetaADEDB
Middle Ear Effusion MetaADEDB
Middle Ear Inflammation MetaADEDB
Mild Mental Retardation MetaADEDB
Mood Disorders MetaADEDB
Mood Swings ADReCS
Morphine Dependence MetaADEDB
Multi-Organ Failure ADReCS
Multiple Allergies MetaADEDB
Multiple Congenital Abnormalities MetaADEDB
Muscle Relaxant Therapy ADReCS
Muscle Spasms ADReCS
Muscle Spasticity ADReCS
Muscle Twitching ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Disorder SIDER
Musculoskeletal Pain ADReCS
Myalgia ADReCS
Myoclonic Epilepsy ADReCS
Myoclonus ADReCS
Nasal Congestion ADReCS
Nasopharyngitis ADReCS
Nausea ADReCS
Necrolysis Epidermal SIDER
Nervous System Disorder SIDER
Nervousness ADReCS
Neumonia MetaADEDB
Neuritis ADReCS
Neurobehavioral Manifestations MetaADEDB
Neuropathy Peripheral ADReCS
Nipple Disorder MetaADEDB
Nystagmus ADReCS
Oedema ADReCS
Oedema Peripheral ADReCS
Oesophagitis ADReCS
Oliguria MetaADEDB
Optic Atrophy ADReCS
Optic Neuritis ADReCS
Optic Neuropathy MetaADEDB
Organ Failure ADReCS
Oropharyngeal Pain ADReCS
Osteoarthritis ADReCS
Otitis SIDER
Otitis Media ADReCS
Otitis Media Acute ADReCS
Pain ADReCS
Pain In Extremity ADReCS
Pallor ADReCS
Paraesthesia ADReCS
Pectus Excavatum MetaADEDB
Penis Disorder MetaADEDB
Personality Disorder ADReCS
Phalangeal Hypoplasia MetaADEDB
Pharyngolaryngeal Pain SIDER
Phimosis MetaADEDB
Photosensitive Rash MetaADEDB
Plagiocephaly MetaADEDB
Platelet Count Abnormal MetaADEDB
Platelet Function Test Abnormal MetaADEDB
Pneumonia ADReCS
Po2 MetaADEDB
Postictal State ADReCS
Posturing MetaADEDB
Premature Labour MetaADEDB
Procedural Complication MetaADEDB
Prothrombin Time MetaADEDB
Pruritus ADReCS
Pseudoporphyria MetaADEDB
Psychoses Substance-Induced MetaADEDB
Psychotic Disorder ADReCS
Psychotic Disorders MetaADEDB
Puberty ADReCS
Pulmonary Congestion ADReCS
Pulmonary Embolism ADReCS
Pupil Fixed MetaADEDB
Purpura ADReCS
Pyloric Stenosis MetaADEDB
Pyrexia ADReCS
Rash ADReCS
Rash Maculo-Papular ADReCS
Rash Papular ADReCS
Reading Disorder MetaADEDB
Recurrence MetaADEDB
Renal Aplasia ADReCS
Respiratory Disorder ADReCS
Respiratory Failure ADReCS
Respiratory Rate Increased MetaADEDB
Respiratory Syncytial Virus Bronchiolitis MetaADEDB
Respiratory Tract Congestion ADReCS
Respiratory Tract Infection ADReCS
Retinal Atrophy SIDER
Retinal Degeneration ADReCS
Retinal Diseases MetaADEDB
Retinal Toxicity MetaADEDB
Retinitis ADReCS
Retinitis Pigmentosa ADReCS
Retrocollis MetaADEDB
Retrognathia MetaADEDB
Salivary Hypersecretion ADReCS
Scotoma ADReCS
Sedation ADReCS
Seizures MetaADEDB
Sensory Disturbance ADReCS
Sensory Loss ADReCS
Shoulder Pain ADReCS
Sinus Headache ADReCS
Sinusitis ADReCS
Skin Disorder ADReCS
Somnolence ADReCS
Spasms Infantile MetaADEDB
Speech Disorder ADReCS
Speech Disorder Developmental MetaADEDB
Speech Impairment Nos SIDER
Status Epilepticus ADReCS
Stomach Discomfort ADReCS
Strabismus ADReCS
Stridor ADReCS
Stupor ADReCS
Substance Withdrawal Syndrome MetaADEDB
Suicide SIDER
Suicide Attempt ADReCS
Supernumerary Nipple ADReCS
Swelling ADReCS
Talipes ADReCS
Tension ADReCS
Thalamic Diseases MetaADEDB
Thinking Abnormal ADReCS
Thirst ADReCS
Throat Irritation ADReCS
Tinnitus ADReCS
Tooth Disorder ADReCS
Toothache ADReCS
Toxic Epidermal Necrolysis ADReCS
Tracheo-Oesophageal Fistula MetaADEDB
Traction MetaADEDB
Tremor ADReCS
Tuberous Sclerosis MetaADEDB
Underweight MetaADEDB
Upper Respiratory Tract Infection ADReCS
Upset Stomach SIDER
Urinary Tract Infection ADReCS
Urinary Tract Infection Pseudomonal MetaADEDB
Urticaria ADReCS
Vascular Purpura ADReCS
Vasculitis Leukocytoclastic Cutaneous MetaADEDB
Vertigo ADReCS
Vesicoureteric Reflux ADReCS
Viral Diarrhoea ADReCS
Viral Infection ADReCS
Vision Blurred ADReCS
Vision Disorders MetaADEDB
Visual Acuity Reduced ADReCS
Visual Field Defect ADReCS
Visual Field Tests Abnormal MetaADEDB
Visual Impairment ADReCS
Vomiting ADReCS
Wave Slowing SIDER
Weight Increased ADReCS
Wound Secretion ADReCS

InAADR: Drug-Protein-ADRs database