InAADR

Drug Information

Drug Name: Promethazine (60-87-7)
PubChem ID: 4927
SMILES: CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C
InchiKey: PWWVAXIEGOYWEE-UHFFFAOYSA-N
Therapeutic Category: Anti-Allergic Agents, Antipruritics, Dermatologic Agents, Histamine Agents, Histamine Antagonists, Histamine H1 Antagonists, Neurotransmitter Agents

Computed Drug Properties

Molecular Weight (dalton): 284.428
LogP: 4.2394
Ring Count: 2
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 6.48

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort MetaADEDB
Abdominal Distension MetaADEDB
Abdominal Pain MetaADEDB
Abdominal Pain MetaADEDB
Abdominal Sepsis MetaADEDB
Abscess ADReCS
Abscess Bacterial MetaADEDB
Abuse MetaADEDB
Accident MetaADEDB
Aching Joints MetaADEDB
Acidosis ADReCS
Acute Brain Syndrome MetaADEDB
Acute Hepatic Failure MetaADEDB
Acute Kidney Injury MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Sinusitis MetaADEDB
Adh Inappropriate MetaADEDB
Administration Site Pain MetaADEDB
Adrenal Disorder MetaADEDB
Adverse Reaction MetaADEDB
Aggression MetaADEDB
Agitated MetaADEDB
Agitation ADReCS
Agranulocytosis ADReCS
Alcohol Abuse MetaADEDB
Allergic Rhinitis MetaADEDB
Alveolitis MetaADEDB
Amyotrophic Lateral Sclerosis MetaADEDB
Anaemia Of Chronic Disease MetaADEDB
Anaemia Of Malignant Disease MetaADEDB
Anaesthesia MetaADEDB
Anger MetaADEDB
Angina MetaADEDB
Angioedema ADReCS
Anisocoria MetaADEDB
Anorexia MetaADEDB
Anoxic Encephalopathy MetaADEDB
Anticholinergic Syndrome MetaADEDB
Anticonvulsant Drug Level Below Therapeutic MetaADEDB
Anxiety ADReCS
Aortic Regurgitation MetaADEDB
Apnea MetaADEDB
Apnoea ADReCS
Apoplexy MetaADEDB
Arrhythmia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arteriovenous Fistula Thrombosis MetaADEDB
Arteriovenous Shunt Operation MetaADEDB
Asphyxia MetaADEDB
Asthenia ADReCS
Asthma ADReCS
Ataxia ADReCS
Athetosis ADReCS
Atrial Ectopic Beats MetaADEDB
Atrial Tachycardia MetaADEDB
Atrioventricular Block Complete MetaADEDB
Attempted Suicide MetaADEDB
Autoimmune Thrombocytopenia MetaADEDB
Azotaemia MetaADEDB
Azotemia MetaADEDB
Back Ache MetaADEDB
Bacteraemia MetaADEDB
Bacterial Toxaemia MetaADEDB
Band Neutrophil Percentage Increased MetaADEDB
Basal Cell Carcinoma MetaADEDB
Bile Duct Stone MetaADEDB
Biliary Dyskinesia MetaADEDB
Bipolar Disorder MetaADEDB
Bladder Inflammation MetaADEDB
Blood Bicarbonate Decreased MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Cholesterol MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Pressure Abnormal ADReCS
Blood Pressure Diastolic Decreased MetaADEDB
Blood Pressure Fluctuation ADReCS
Blood Prolactin Increased MetaADEDB
Blood Sodium MetaADEDB
Blurred Vision MetaADEDB
Body Temperature MetaADEDB
Body Temperature Increased MetaADEDB
Bone Cancer Metastatic MetaADEDB
Bone Lesion MetaADEDB
Bradycardia ADReCS
Bradypnoea MetaADEDB
Brain Damage MetaADEDB
Brain Death MetaADEDB
Breast Discomfort MetaADEDB
Breast Enlargement MetaADEDB
Bronchitis MetaADEDB
Bronchitis MetaADEDB
Bronchoscopy MetaADEDB
Bulging MetaADEDB
Bullous Lung Disease MetaADEDB
Bunion MetaADEDB
Burning Sensation ADReCS
Caesarean Section MetaADEDB
Candida Infection MetaADEDB
Cardiac Asthma MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Operation MetaADEDB
Cardiac Output Decreased MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardioactive Drug Level Increased MetaADEDB
Cardiomyopathy MetaADEDB
Catalepsy MetaADEDB
Catatonia ADReCS
Catheter Related Complication MetaADEDB
Catheter Related Infection MetaADEDB
Caustic Injury MetaADEDB
Cellulitis MetaADEDB
Central Venous Catheterisation MetaADEDB
Cerebellar Ischaemia MetaADEDB
Cerebral Artery Stenosis MetaADEDB
Cerebral Atherosclerosis MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebrospinal Fluid Leakage MetaADEDB
Cervicalgia MetaADEDB
Chest Infection MetaADEDB
Chest Pain ADReCS
Choking Sensation MetaADEDB
Cholecystitis Chronic MetaADEDB
Cholecystitis Infective MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Chronic Obstructive Airways Disease Exacerbated MetaADEDB
Chronic Sinusitis MetaADEDB
Clostridial Infection MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Cognition Disorders MetaADEDB
Coma MetaADEDB
Confusional State ADReCS
Constipated MetaADEDB
Contact Dermatitis MetaADEDB
Conversion Disorder ADReCS
Convulsion ADReCS
Convulsive Seizure SIDER
Coordination Abnormal ADReCS
Coronary Artery Occlusion MetaADEDB
Coronary Artery Stenosis MetaADEDB
Costochondritis MetaADEDB
Cough MetaADEDB
Coughing Blood MetaADEDB
Cubital Tunnel Syndrome MetaADEDB
Cystocele MetaADEDB
Deafness MetaADEDB
Death ADReCS
Deglutition Disorder MetaADEDB
Dehydration MetaADEDB
Delirium ADReCS
Demyelination MetaADEDB
Dermatitis ADReCS
Dermatitis Exfoliative MetaADEDB
Dermatosis MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetes Mellitus Insulin-Dependent MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Acidosis MetaADEDB
Diabetic Hyperosmolar Coma MetaADEDB
Diabetic Neuropathy MetaADEDB
Diabetic Retinopathy MetaADEDB
Diarrhea MetaADEDB
Dilatation Ventricular MetaADEDB
Diplopia ADReCS
Disorder Of Globe MetaADEDB
Disorders Of Excessive Somnolence MetaADEDB
Disorientation ADReCS
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drowsiness SIDER
Drug Dose Omission MetaADEDB
Drug Hypersensitivity MetaADEDB
Drug Screen Positive MetaADEDB
Drug Withdrawal Convulsions MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Mouth ADReCS
Duodenal Polyp MetaADEDB
Dysgraphia MetaADEDB
Dyskinesia ADReCS
Dyskinesia Drug-Induced MetaADEDB
Dyspepsia MetaADEDB
Dysplastic Naevus Syndrome MetaADEDB
Dystonia MetaADEDB
Dystonic Disorders MetaADEDB
Dysuria MetaADEDB
Ear Disorder MetaADEDB
Early Morning Awakening MetaADEDB
Economic Problem MetaADEDB
Edema MetaADEDB
Edema Extremities MetaADEDB
Ejection Fraction Decreased MetaADEDB
Elderly ADReCS
Electrocardiogram St Segment Abnormal MetaADEDB
Electrolyte Disorder MetaADEDB
Embolism Pulmonary MetaADEDB
Emesis MetaADEDB
Emotional Distress MetaADEDB
Encephalitis MetaADEDB
Encephalopathy MetaADEDB
Endotracheal Intubation MetaADEDB
Enlarged Liver MetaADEDB
Enterocolitis MetaADEDB
Erythema ADReCS
Euphoric Mood ADReCS
Extensor Plantar Response SIDER
Extrapyramidal Disorder ADReCS
Extrapyramidal Symptoms SIDER
Extravasation ADReCS
Extremity Necrosis MetaADEDB
Extremity Pain MetaADEDB
Eye Infection Bacterial MetaADEDB
Eye Pain MetaADEDB
Facial Flushing MetaADEDB
Facial Palsy MetaADEDB
Fatigue ADReCS
Fatty Liver MetaADEDB
Febrile Neutropenia MetaADEDB
Feeling Abnormal ADReCS
Feeling Cold MetaADEDB
Fetal Distress MetaADEDB
Fever MetaADEDB
Fib MetaADEDB
Fibrin D Dimer MetaADEDB
Fibromyalgia MetaADEDB
Flatulence MetaADEDB
Flu MetaADEDB
Fluid Overload MetaADEDB
Flushing ADReCS
Gangrene ADReCS
Gastric Dilatation MetaADEDB
Gastric Disorder MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Disorder ADReCS
Gastrointestinal Stromal Tumour MetaADEDB
Gastrointestinal Symptom Nos SIDER
Glucose Intolerance MetaADEDB
Granulocytosis MetaADEDB
Granuloma MetaADEDB
Haematoma MetaADEDB
Haemolysis MetaADEDB
Hallucination ADReCS
Hallucinations MetaADEDB
Headache MetaADEDB
Heart Arrest MetaADEDB
Heart Attack MetaADEDB
Heart Rate Increased MetaADEDB
Heparin-Induced Thrombocytopenia MetaADEDB
Hepatic Failure MetaADEDB
Hepatobiliary Scan MetaADEDB
Hernia Hiatal MetaADEDB
Herpes Zoster MetaADEDB
Hip Arthroplasty MetaADEDB
Hospitalisation MetaADEDB
Hyperacusia MetaADEDB
Hyperalgesia MetaADEDB
Hyperammonaemia MetaADEDB
Hyperexcitation SIDER
Hyperhidrosis MetaADEDB
Hyperkalemia MetaADEDB
Hyperkinesis MetaADEDB
Hyperlipaemia MetaADEDB
Hypermagnesaemia MetaADEDB
Hypernatremia MetaADEDB
Hyperphosphatemia MetaADEDB
Hyperreflexia ADReCS
Hypersensitivity MetaADEDB
Hypertension ADReCS
Hypertonia ADReCS
Hypoaesthesia MetaADEDB
Hypocalcemia MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypokalaemia MetaADEDB
Hypotension ADReCS
Hypothyroid MetaADEDB
Hypovolaemia MetaADEDB
Hypoxia MetaADEDB
Hysteria ADReCS
Iliac Artery Thrombosis MetaADEDB
Impaired Gastric Emptying MetaADEDB
Implant Site Haemorrhage MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection Urinary Tract MetaADEDB
Infection Viral MetaADEDB
Influenza Like Illness MetaADEDB
Ingrowing Nail MetaADEDB
Initial Insomnia MetaADEDB
Injection Site Infection MetaADEDB
Injection Site Injury MetaADEDB
Injection Site Phlebitis ADReCS
Injection Site Reaction ADReCS
Insomnia ADReCS
Intervertebral Disc Degeneration MetaADEDB
Intra-abdominal haematoma MetaADEDB
Intra-Abdominal Haemorrhage MetaADEDB
Intraocular Pressure Decreased MetaADEDB
Jaundice ADReCS
Jaw Operation MetaADEDB
Joint Effusion MetaADEDB
Joint Sprain MetaADEDB
Kidney Enlargement MetaADEDB
Kidney Failure MetaADEDB
Labour Pain MetaADEDB
Laryngeal Stenosis MetaADEDB
Lassitude SIDER
Left Ventricular Dysfunction MetaADEDB
Leukocytosis MetaADEDB
Leukoencephalopathy MetaADEDB
Leukopenia ADReCS
Light Sensitivity MetaADEDB
Lip Erosion MetaADEDB
Lipase MetaADEDB
Long Qt Syndrome MetaADEDB
Loss Of Consciousness ADReCS
Loss Of Weight MetaADEDB
Lower Gastrointestinal Haemorrhage MetaADEDB
Lung Edema MetaADEDB
Lung Neoplasm MetaADEDB
Malignant Melanoma MetaADEDB
Malignant Syndrome Nos SIDER
Malnourished MetaADEDB
Maxillofacial Operation MetaADEDB
Mental Disorder MetaADEDB
Mental Status Changes MetaADEDB
Middle Ear Effusion MetaADEDB
Migraine MetaADEDB
Mitral Valve Prolapse MetaADEDB
Motion Sickness MetaADEDB
Movement Disorder ADReCS
Mucosal Erosion MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Multiple Injuries MetaADEDB
Muscle Hypertonia MetaADEDB
Muscle Spasms ADReCS
Muscle Weakness MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Chest Pain MetaADEDB
Musculoskeletal Pain MetaADEDB
Mydriasis ADReCS
Myoclonus MetaADEDB
Myoglobinuria MetaADEDB
Nail Operation MetaADEDB
Nasal Congestion ADReCS
Nasopharyngitis MetaADEDB
Nausea ADReCS
Necrosis ADReCS
Neoplasm Progression MetaADEDB
Nephritic Syndrome MetaADEDB
Nephritis Interstitial MetaADEDB
Nervous Tension MetaADEDB
Nervousness ADReCS
Neumonia MetaADEDB
Neurogenic Bladder MetaADEDB
Neuroleptic Malignant Syndrome ADReCS
Nightmare ADReCS
Nikolsky Sign MetaADEDB
Nocturia MetaADEDB
Non-Cardiac Chest Pain MetaADEDB
Oculogyric Crisis ADReCS
Oedema ADReCS
Oedema Due To Cardiac Disease MetaADEDB
Oral Fungal Infection MetaADEDB
Osteoarthritis MetaADEDB
Osteosclerosis MetaADEDB
Otitis Media MetaADEDB
Overdose MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Palpitation MetaADEDB
Pancreaticoduodenectomy MetaADEDB
Pancreatitis MetaADEDB
Pancreatitis Chronic MetaADEDB
Paralysis ADReCS
Paranoid Disorders MetaADEDB
Paresis MetaADEDB
Pedal Pulse Absent MetaADEDB
Pelvic Prolapse MetaADEDB
Pericardial Effusion MetaADEDB
Peripheral Embolism MetaADEDB
Pharmaceutical Product Complaint MetaADEDB
Pharyngitis MetaADEDB
Pharyngitis Streptococcal MetaADEDB
Phlebitis ADReCS
Phlebothrombosis MetaADEDB
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Piloerection MetaADEDB
Pleural Adhesion MetaADEDB
Pleural Decortication MetaADEDB
Pneumonia Aspiration MetaADEDB
Pneumonia Haemophilus MetaADEDB
Polyneuropathy MetaADEDB
Post Procedural Infection MetaADEDB
Postoperative Complications MetaADEDB
Postoperative Nausea And Vomiting MetaADEDB
Premature Baby MetaADEDB
Premature Labour MetaADEDB
Procedural Complication MetaADEDB
Progesterone Increased MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Protrusion Tongue ADReCS
Pseudomonas Infection MetaADEDB
Psychoses MetaADEDB
Psychoses Substance-Induced MetaADEDB
Psychosexual Disorder MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Function Test Decreased ADReCS
Pulmonary Hypertension MetaADEDB
Pupillary Reflex Impaired MetaADEDB
Purpura ADReCS
Pustular Psoriasis MetaADEDB
Radiotherapy MetaADEDB
Rash ADReCS
Reaction To Drug Excipient MetaADEDB
Renal Lipomatosis MetaADEDB
Renal Tubular Acidosis MetaADEDB
Renal Tubular Necrosis MetaADEDB
Respiratory Depression ADReCS
Respiratory Distress ADReCS
Respiratory Insufficiency MetaADEDB
Respiratory Rate Increased MetaADEDB
Restlessness ADReCS
Rheumatic Fever MetaADEDB
Rhonchi MetaADEDB
Rib Fracture MetaADEDB
Road Traffic Accident MetaADEDB
Schizophrenia MetaADEDB
Scoliosis MetaADEDB
Sedation ADReCS
Seizures SIDER
Sensory Loss ADReCS
Septic Shock MetaADEDB
Serratia Bacteraemia MetaADEDB
Shock ADReCS
Sinusitis MetaADEDB
Skin Discolouration MetaADEDB
Sleep Apnea Central MetaADEDB
Sleep Apnea Obstructive MetaADEDB
Sleep Apnea Syndromes MetaADEDB
Soft Tissue Necrosis ADReCS
Somnolence ADReCS
Speech Disorder MetaADEDB
Spinal Fracture MetaADEDB
Spinal Osteoarthritis MetaADEDB
Spondylolisthesis MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Staphylococcal Infection MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Stress Incontinence MetaADEDB
Stupor MetaADEDB
Substance Abuse Intravenous MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Sudden Cardiac Death MetaADEDB
Sudden Death ADReCS
Surgery ADReCS
Surgical Intervention SIDER
Swelling ADReCS
Syncope ADReCS
Tachycardia ADReCS
Tachycardia Sinus MetaADEDB
Tachycardia Ventricular MetaADEDB
Tension ADReCS
Therapeutic Response Decreased MetaADEDB
Thrombocytopenia ADReCS
Thrombocytopenic Purpura ADReCS
Thrombophlebitis ADReCS
Thrombosis ADReCS
Thyroid Neoplasia MetaADEDB
Tibia Fracture MetaADEDB
Tinnitus ADReCS
Tonsillitis MetaADEDB
Torsades De Pointes MetaADEDB
Torticollis ADReCS
Tracheal Fistula MetaADEDB
Transient Ischaemic Attack MetaADEDB
Tremor ADReCS
Unevaluable Event MetaADEDB
Unresponsive To Stimuli MetaADEDB
Upper Limb Fracture MetaADEDB
Urinary Tract Infection Enterococcal MetaADEDB
Urticaria ADReCS
Vaginal Prolapse MetaADEDB
Vascular Graft Occlusion MetaADEDB
Vascular Purpura ADReCS
Vasospasm ADReCS
Venous Insufficiency MetaADEDB
Venous Thrombosis ADReCS
Vision Blurred ADReCS
Visual Disturbance MetaADEDB
Vomiting ADReCS
Wheeze MetaADEDB
Wrong Technique In Drug Usage Process MetaADEDB

InAADR: Drug-Protein-ADRs database