| Drug Name: | Megestrol acetate (595-33-5) |
|---|---|
| PubChem ID: | 11683 |
| SMILES: | CC1=C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@@]3(C(=O)C)OC(=O)C)C)[C@@]4(C1=CC(=O)CC4)C |
| InchiKey: | RQZAXGRLVPAYTJ-GQFGMJRRSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 384.516 |
| LogP | : | 4.5753 |
| Ring Count | : | 0 |
| Hydrogen Bond Acceptor Count | : | 4 |
| Hydrogen Bond Donor Count | : | 0 |
| Total Polar Surface Area | : | 60.44 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Cisplatin (15663-27-1) | Reduced The Response Rates | Antagonistic | in vitro study found that megestrol may antagonise the antineoplastic activity of cisplatin by up-regulating cellular detoxification mechanisms | Megestrol acetate antagonizes cisplatin cytotoxicity |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category