| Drug Name: | Nafazatrom (59040-30-1) |
|---|---|
| PubChem ID: | 42923 |
| SMILES: | CC1=NN(C(=O)C1)CCOC2=CC3=CC=CC=C3C=C2 |
| InchiKey: | ISBUYSPRIJRBKX-UHFFFAOYSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 268.316 |
| LogP | : | 2.8268 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 3 |
| Hydrogen Bond Donor Count | : | 0 |
| Total Polar Surface Area | : | 41.9 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Inactivation Of Phs | Prostaglandin G/H synthase 1 precursor (P23219) | Oxygenated derivative of PB@ rather than the parent compound@ which is responsible for the inactivation of PHS and prostacyclin synthase@blocks the effects of the PB and H2O2 treatment. [ ADR Type 1 ] | Inactivation of prostaglandin H synthase and prostacyclin synthase by phenylbutazone Requirement for peroxidative metabolism |
| Inactivation Of Phs And Prostacyclin Synthase | Prostacyclin synthase (Q16647) | Oxygenated derivative of PB@ rather than the parent compound@ which is responsible for the inactivation of PHS and prostacyclin synthase@blocks the effects of the PB and H2O2 treatment [ ADR Type 1 ] | Inactivation of prostaglandin H synthase and prostacyclin synthase by phenylbutazone Requirement for peroxidative metabolism |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category
| Toxicity | Source |
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