InAADR

Drug Information

Drug Name: Neostigmine (59-99-4)
PubChem ID: 4456
SMILES: CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C
InchiKey: ALWKGYPQUAPLQC-UHFFFAOYSA-N
Therapeutic Category: Autonomic Agents, Cholinergic Agents, Cholinesterase Inhibitors, Enzyme Inhibitors, Neurotransmitter Agents, Parasympathomimetics, Peripheral Nervous System Agents

Computed Drug Properties

Molecular Weight (dalton): 223.296
LogP: 1.9437
Ring Count: 1
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 29.54

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Compartment Syndrome MetaADEDB
Abdominal Discomfort MetaADEDB
Abdominal Distension MetaADEDB
Abdominal Pain MetaADEDB
Abnormal Movements MetaADEDB
Abscess MetaADEDB
Aching Joints MetaADEDB
Acidosis MetaADEDB
Actinic Keratosis MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Otitis Media MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adenopathy MetaADEDB
Adnexa Uteri Mass MetaADEDB
Adnexitis MetaADEDB
Adynamic Ileus MetaADEDB
Agitated MetaADEDB
Agranulocytoses MetaADEDB
Agraphia MetaADEDB
Airway Obstruction MetaADEDB
Akinesia MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alopecia MetaADEDB
Altered State Of Consciousness MetaADEDB
Amnesia MetaADEDB
Amyotrophy MetaADEDB
Anaemia MetaADEDB
Anaemia Postoperative MetaADEDB
Anaphylactic Shock ADReCS
Angina MetaADEDB
Angle Closure Glaucoma MetaADEDB
Anhedonia MetaADEDB
Anisocoria MetaADEDB
Anxiety MetaADEDB
Aortic Bruit MetaADEDB
Aphthous Stomatitis MetaADEDB
Apnea MetaADEDB
Arrhythmia ADReCS
Arterial Occlusive Disease MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis Coronary Artery MetaADEDB
Arthralgia ADReCS
Arthritis MetaADEDB
Aseptic Necrosis Bone MetaADEDB
Aspergillosis MetaADEDB
Asphyxia MetaADEDB
Asthenia ADReCS
Asystole MetaADEDB
Atrial Ectopic Beats MetaADEDB
Atrial Tachycardia MetaADEDB
Atrioventricular Block ADReCS
Autologous Bone Marrow Transplantation Therapy MetaADEDB
Automatism MetaADEDB
Back Ache MetaADEDB
Bacteraemia MetaADEDB
Balance Disorder MetaADEDB
Bedridden MetaADEDB
Bile Duct Obstruction MetaADEDB
Bile Duct Stone MetaADEDB
Birth Defect MetaADEDB
Bladder Retention MetaADEDB
Bleeding Gums MetaADEDB
Blepharoptosis MetaADEDB
Blindness Transient MetaADEDB
Blood Calcium MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Glucose Abnormal MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood In Urine MetaADEDB
Blood Phosphorus Decreased MetaADEDB
Blood Sodium MetaADEDB
Bone Cancer Metastatic MetaADEDB
Bone Debridement MetaADEDB
Bone Disorder MetaADEDB
Bone Lesion MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Operation MetaADEDB
Bone Pain MetaADEDB
Bradycardia ADReCS
Bradypnoea MetaADEDB
Brain Compression MetaADEDB
Brain Oedema MetaADEDB
Brain Stem Infarction MetaADEDB
Breast Calcifications MetaADEDB
Breast Cancer In Situ MetaADEDB
Breast Lump MetaADEDB
Breast Lump Removal MetaADEDB
Breast Operation MetaADEDB
Bronchitis MetaADEDB
Bronchospasm ADReCS
Bruise MetaADEDB
Bulging MetaADEDB
Cachectic MetaADEDB
Carcinoid Syndrome MetaADEDB
Carcinoma Of Prostate MetaADEDB
Cardiac Arrest ADReCS
Cardiac Murmur MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiomegaly MetaADEDB
Carotid Bruit MetaADEDB
Cataract Operation MetaADEDB
Cellulitis MetaADEDB
Central Venous Catheterisation MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cerebral Infarct MetaADEDB
Cervicalgia MetaADEDB
Cervicobrachial Syndrome MetaADEDB
Chest Pain MetaADEDB
Chill MetaADEDB
Cholecystectomies MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Chronic Ulcerative Colitis MetaADEDB
Clonus MetaADEDB
Clotting MetaADEDB
Colon Spastic MetaADEDB
Colonic Polyp MetaADEDB
Condition Aggravated MetaADEDB
Constipated MetaADEDB
Constipation MetaADEDB
Contact Dermatitis MetaADEDB
Conversion Disorder MetaADEDB
Convulsion ADReCS
Cough MetaADEDB
Cramp Muscle SIDER
Csf Protein MetaADEDB
Cutaneous Ulcer MetaADEDB
Cyst MetaADEDB
Deafness Congenital MetaADEDB
Debridement MetaADEDB
Decreased Interest MetaADEDB
Deep Vein Thromboses MetaADEDB
Deglutition Disorder MetaADEDB
Dehydration MetaADEDB
Delayed Recovery From Anaesthesia MetaADEDB
Demyelination MetaADEDB
Dental Abscess MetaADEDB
Dental Caries MetaADEDB
Dental Operation MetaADEDB
Depressed Mood MetaADEDB
Dermatitis ADReCS
Diabetes MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Disease Of Liver MetaADEDB
Disorder Peripheral Vascular MetaADEDB
Disorder Renal MetaADEDB
Disturbance In Attention MetaADEDB
Diverticulitis MetaADEDB
Diverticulum MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drowsiness SIDER
Drug Resistance MetaADEDB
Dysarthria ADReCS
Dyspnoea ADReCS
Dyspnoea Paroxysmal Nocturnal MetaADEDB
Dysuria MetaADEDB
Ear Infection MetaADEDB
Early Morning Awakening MetaADEDB
Electrocardiogram Abnormal ADReCS
Embolism Pulmonary MetaADEDB
Emesis MetaADEDB
Emphysema MetaADEDB
Empyema MetaADEDB
Encephalitis MetaADEDB
Endodontic Procedure MetaADEDB
Enlarged Liver MetaADEDB
Erectile Dysfunction MetaADEDB
Excess Potassium MetaADEDB
Excoriation MetaADEDB
Faecaloma MetaADEDB
Failure To Anastomose MetaADEDB
Fasciculation SIDER
Fatigue MetaADEDB
Feeding Tube Insertion MetaADEDB
Fibroids MetaADEDB
Flatulence ADReCS
Flushing ADReCS
Formication MetaADEDB
Fusarium Infection MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastrointestinal Hypermotility ADReCS
Gastrointestinal Pain ADReCS
Gastrointestinal Surgery MetaADEDB
Gingival Erythema MetaADEDB
Gingival Oedema MetaADEDB
Gingival Pain MetaADEDB
Granulocytosis MetaADEDB
Gynaecomastia MetaADEDB
Haematemesis MetaADEDB
Haemodialysis MetaADEDB
Haemolytic Anaemia MetaADEDB
Haemorrhoid Operation MetaADEDB
Headache ADReCS
Heart Block MetaADEDB
Heart Rate Increased MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatic Necrosis MetaADEDB
Hepatosplenomegaly MetaADEDB
Hernia Hiatal MetaADEDB
Histiocytosis Haematophagic MetaADEDB
Hot Flash MetaADEDB
Hyperalgesia MetaADEDB
Hyperammonaemia MetaADEDB
Hypercapnia MetaADEDB
Hypergammaglobulinaemia MetaADEDB
Hyperglycemia MetaADEDB
Hyperhidrosis ADReCS
Hyperlipaemia MetaADEDB
Hypersensitivity ADReCS
Hypertension MetaADEDB
Hypertonia MetaADEDB
Hypoaesthesia MetaADEDB
Hypokinesia MetaADEDB
Hypomagnesaemia MetaADEDB
Hypotension ADReCS
Hypotension Orthostatic MetaADEDB
Hypothermia MetaADEDB
Hypovolaemic Shock MetaADEDB
Hypoxia MetaADEDB
Hysterectomy MetaADEDB
Iliac Artery Occlusion MetaADEDB
Impaired Gastric Emptying MetaADEDB
Impaired Healing MetaADEDB
Increased Upper Airway Secretion ADReCS
Increased White Blood Cell Count MetaADEDB
Infection MetaADEDB
Infection Upper Respiratory MetaADEDB
Infection Urinary Tract MetaADEDB
International Normalised Ratio Decreased MetaADEDB
Intervertebral Disc Degeneration MetaADEDB
Intervertebral Disc Herniation MetaADEDB
Intestinal Cramps ADReCS
Intestinal Obstruction MetaADEDB
Intraocular Lens Implant MetaADEDB
Jaw Operation MetaADEDB
Joint Effusion MetaADEDB
Joint Lock MetaADEDB
Joint Sprain MetaADEDB
Knee Arthroplasty MetaADEDB
Labor Pain MetaADEDB
Lacrimation Increased MetaADEDB
Large Intestine Perforation MetaADEDB
Long Qt Syndrome MetaADEDB
Loss Of Consciousness ADReCS
Loss Of Weight MetaADEDB
Low Density Lipoprotein Decreased MetaADEDB
Lung Fibrosis MetaADEDB
Lung Infiltration MetaADEDB
Lung Lobectomy MetaADEDB
Lung Neoplasm MetaADEDB
Lung Transplant MetaADEDB
Lyell MetaADEDB
Lymphadenectomy MetaADEDB
Lymphadenopathy Mediastinal MetaADEDB
Lymphocyte Stimulation Test Positive MetaADEDB
Maculopathy MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Mean Cell Haemoglobin Concentration Increased MetaADEDB
Mediastinoscopy MetaADEDB
Metastases To Adrenals MetaADEDB
Metastases To Central Nervous System MetaADEDB
Metastases To Lung MetaADEDB
Metastases To Neck MetaADEDB
Micturition Urgency MetaADEDB
Miosis ADReCS
Mood Disorder Due To A General Medical Condition MetaADEDB
Mouth Pain MetaADEDB
Mucosal Inflammation MetaADEDB
Multi-Organ Failure MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Contractions Involuntary ADReCS
Muscle Necrosis MetaADEDB
Muscle Spasms ADReCS
Muscle Weakness MetaADEDB
Muscular Diseases MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Pain MetaADEDB
Myasthenia Gravis MetaADEDB
Nasopharyngitis MetaADEDB
Nausea ADReCS
Nephrolithiasis MetaADEDB
Neuromuscular Block Prolonged MetaADEDB
Neuropathy Peripheral MetaADEDB
No Therapeutic Response MetaADEDB
Nodal Rhythm ADReCS
Nutritional Condition Abnormal MetaADEDB
Nystagmus MetaADEDB
Oliguria MetaADEDB
Oophorectomy Bilateral MetaADEDB
Operative Haemorrhage MetaADEDB
Oral Cavity Fistula MetaADEDB
Oral Disorder MetaADEDB
Oral Polypectomy MetaADEDB
Oral Surgery MetaADEDB
Oroantral Fistula MetaADEDB
Osteoarthritis ADReCS
Osteolysis MetaADEDB
Osteomyelitis MetaADEDB
Osteopenia MetaADEDB
Osteoporosis MetaADEDB
Osteosarcoma Metastatic MetaADEDB
Ovarian Mass MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain MetaADEDB
Pain Postoperative MetaADEDB
Panic Attack MetaADEDB
Paralysis MetaADEDB
Paraneoplastic Syndrome MetaADEDB
Pelvic Infection MetaADEDB
Pericardial Effusion MetaADEDB
Periodic Limb Movement Disorder MetaADEDB
Peritonitis MetaADEDB
Phaeochromocytoma MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pneumonia Mycoplasmal MetaADEDB
Pollakiuria ADReCS
Polymyalgia Rheumatica MetaADEDB
Post Procedural Complication MetaADEDB
Post Procedural Haemorrhage MetaADEDB
Postoperative Complications MetaADEDB
Presbyacusis MetaADEDB
Primary Sequestrum MetaADEDB
Procedural Complication MetaADEDB
Procedural Hypotension MetaADEDB
Procedural Pain MetaADEDB
Proctalgia MetaADEDB
Prostate Cancer Recurrent MetaADEDB
Protein Total Increased MetaADEDB
Psychoses MetaADEDB
Pulmonary Function Test Decreased ADReCS
Pulmonary Hypertension MetaADEDB
Pulmonary Infarction MetaADEDB
Pulmonary Mass MetaADEDB
Pulmonary Thrombosis MetaADEDB
Purulent Discharge MetaADEDB
Rash ADReCS
Red Blood Cell Abnormality MetaADEDB
Regressive Behaviour MetaADEDB
Renal Artery Occlusion MetaADEDB
Respiration Abnormal MetaADEDB
Respiratory Arrest ADReCS
Respiratory Depression ADReCS
Respiratory Disorder MetaADEDB
Respiratory Failure MetaADEDB
Respiratory Paralysis MetaADEDB
Respiratory Rate Increased MetaADEDB
Reversible Posterior Leukoencephalopathy Syndrome MetaADEDB
Rib Fracture MetaADEDB
Salivary Hypersecretion ADReCS
Salivation SIDER
Seizures MetaADEDB
Septic Shock MetaADEDB
Shock ADReCS
Sick Sinus Syndrome MetaADEDB
Sinus Disorder MetaADEDB
Sinus Operation MetaADEDB
Sinus Rhythm MetaADEDB
Sinusitis MetaADEDB
Sjogren Syndrome MetaADEDB
Skin Induration MetaADEDB
Sleep Apnea MetaADEDB
Small Intestinal Obstruction MetaADEDB
Somnolence ADReCS
Spasm MetaADEDB
Sphincter Of Oddi Dysfunction MetaADEDB
Spinal Column Stenosis MetaADEDB
Spinal Compression Fracture MetaADEDB
Spinal Cord Operation MetaADEDB
Spinal Disorder MetaADEDB
Spinal Osteoarthritis MetaADEDB
Spondylolisthesis MetaADEDB
Stem Cell Transplant MetaADEDB
Stress Cardiomyopathy MetaADEDB
Stridor MetaADEDB
Subileus MetaADEDB
Surgical Procedure Repeated MetaADEDB
Sweating Increased SIDER
Swollen Tongue MetaADEDB
Syncope ADReCS
Synovial Cyst MetaADEDB
Tachycardia ADReCS
Tendinitis MetaADEDB
Thoracotomy MetaADEDB
Thyroid Disease MetaADEDB
Tinea Cruris MetaADEDB
Tooth Extraction MetaADEDB
Tooth Fracture MetaADEDB
Tooth Impacted MetaADEDB
Torsade De Pointes MetaADEDB
Tremor MetaADEDB
Trismus MetaADEDB
Unresponsive To Stimuli MetaADEDB
Urinary Retention MetaADEDB
Urine Flow Decreased MetaADEDB
Urticaria ADReCS
Uterine Atrophy MetaADEDB
Vascular Injury MetaADEDB
Venous Insufficiency MetaADEDB
Ventricular Fibrillation MetaADEDB
Visual Impairment ADReCS
Vomiting ADReCS
Weakness SIDER
Wound Treatment MetaADEDB

InAADR: Drug-Protein-ADRs database