| Drug Name: | Lindane (58-89-9) |
|---|---|
| PubChem ID: | 727 |
| SMILES: | C1(C(C(C(C(C1Cl)Cl)Cl)Cl)Cl)Cl |
| InchiKey: | JLYXXMFPNIAWKQ-UHFFFAOYSA-N |
| Therapeutic Category: | Insecticides, Pesticides |
| Molecular Weight (dalton) | : | 290.832 |
| LogP | : | 3.6444 |
| Ring Count | : | 0 |
| Hydrogen Bond Acceptor Count | : | 0 |
| Hydrogen Bond Donor Count | : | 0 |
| Total Polar Surface Area | : | 0 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Affect Fatty Acid Synthesis | Citrate cleavage enzyme (P53396) | Lindane in the refeeding diet blunted this overshoot of FAS and CCE activities in a dose-dependent manner@suggesting that lindane and PCBs affect fatty acid synthesis at opposite points. [ ADR Type 1 ] | A The effect of gamma-hexachlorocyclohexane (lindane) on the activities of liver lipogenic enzymes and on serum lipids in rats Z Naturforsch [C] |
| Affect Fatty Acid Synthesis | Fatty acid synthase (P49327) | Lindane in the refeeding diet blunted this overshoot of FAS and CCE activities in a dose-dependent manner@suggesting that lindane and PCBs affect fatty acid synthesis at opposite points [ ADR Type 1 ] | A The effect of gamma-hexachlorocyclohexane (lindane) on the activities of liver lipogenic enzymes and on serum lipids in rats Z Naturforsch [C] |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category