| Drug Name: | Caffeine (58-08-2) |
|---|---|
| PubChem ID: | 2519 |
| SMILES: | CN1C=NC2=C1C(=O)N(C(=O)N2C)C |
| InchiKey: | RYYVLZVUVIJVGH-UHFFFAOYSA-N |
| Therapeutic Category: | Central Nervous System Agents, Central Nervous System Stimulants, Enzyme Inhibitors, Neurotransmitter Agents, Phosphodiesterase Inhibitors, Purinergic Agents, Purinergic Antagonists, Purinergic P1 Receptor Antagonists |
| Molecular Weight (dalton) | : | 194.194 |
| LogP | : | -1.0293 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 6 |
| Hydrogen Bond Donor Count | : | 0 |
| Total Polar Surface Area | : | 61.82 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Hepatotoxicity | Metallothionein (P04731) | Caffeine reduced significantly the magnitude of ACM-induced mobilization of cadmium from hepatic cadmium-Metallothionein stores,which leads to acetaminophen-induced hepatotoxicity. [ ADR Type 1 ] | Acetaminophen-induced hepatotoxicity: antagonistic action of caffeine in mice |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category