InAADR

Drug Information

Drug Name: Brotizolam (57801-81-7)
PubChem ID: 2451
SMILES: CC1=NN=C2N1C3=C(C=C(S3)Br)C(=NC2)C4=CC=CC=C4Cl
InchiKey: UMSGKTJDUHERQW-UHFFFAOYSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 393.697
LogP: 4.40412
Ring Count: 3
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 43.07

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Symptom MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Laboratory Findings MetaADEDB
Abuse MetaADEDB
Acne MetaADEDB
Acquired Epidermolysis Bullosa MetaADEDB
Activation Syndrome MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adh Inappropriate MetaADEDB
Adynamic Ileus MetaADEDB
Affect Lability MetaADEDB
Aggression MetaADEDB
Agranulocytoses MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcohol Intolerance MetaADEDB
Alcoholic Intoxication MetaADEDB
Allergic Alveolitis MetaADEDB
Altered State Of Consciousness MetaADEDB
Alveolitis MetaADEDB
Amentia MetaADEDB
Ammonia Increased MetaADEDB
Anaemia MetaADEDB
Anal Haemorrhage MetaADEDB
Angiitis MetaADEDB
Anorexia MetaADEDB
Anuria MetaADEDB
Apathy MetaADEDB
Arteritis MetaADEDB
Arthritis Reactive MetaADEDB
Ascites MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspiration Pneumonia MetaADEDB
Attempted Suicide MetaADEDB
Bacterial Infection MetaADEDB
Bacterial Pneumonia MetaADEDB
Bacterial Toxaemia MetaADEDB
Band Neutrophil Percentage Decreased MetaADEDB
Band Neutrophil Percentage Increased MetaADEDB
Basedow Disease MetaADEDB
Basophil Percentage Increased MetaADEDB
Bence Jones Protein Urine MetaADEDB
Bile Duct Obstruction MetaADEDB
Biliary Anastomosis MetaADEDB
Biliary Fibrosis MetaADEDB
Biliary Tract Infection MetaADEDB
Bladder Cancer Recurrent MetaADEDB
Bladder Inflammation MetaADEDB
Bleb MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Albumin Increased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Amylase Decreased MetaADEDB
Blood Beta-D-Glucan Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Cholinesterase Decreased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Osmolarity Decreased MetaADEDB
Blood Phosphorus Decreased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Sodium Increased MetaADEDB
Blood Urea Decreased MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Blood Uric Acid Decreased MetaADEDB
Blood Urine Present MetaADEDB
Body Temperature Increased MetaADEDB
Bone Marrow Failure MetaADEDB
Brain Damage MetaADEDB
Buccal Mucosal Roughening MetaADEDB
Bulbar Palsy MetaADEDB
Burning Sensation Mucosal MetaADEDB
C-Reactive Protein Increased MetaADEDB
Candida Sepsis MetaADEDB
Carcinoid Syndrome MetaADEDB
Carcinoma Of Prostate MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Failure Acute MetaADEDB
Cardiac Function Test Abnormal MetaADEDB
Cardiac Rehabilitation Therapy MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiomyopathy MetaADEDB
Cataract MetaADEDB
Catatonia MetaADEDB
Catheterisation Cardiac MetaADEDB
Cerebral Artery Stenosis MetaADEDB
Cerebral Infarct MetaADEDB
Chill MetaADEDB
Cholangiolitis MetaADEDB
Cholecystitis MetaADEDB
Cmv Infection MetaADEDB
Colitis Ischaemic MetaADEDB
Colitis Pseudomembranous MetaADEDB
Condition Aggravated MetaADEDB
Conjunctival Hyperaemia MetaADEDB
Craniotomy MetaADEDB
Csf Lymphocyte Count Increased MetaADEDB
Csf Monocyte Count Decreased MetaADEDB
Csf Monocyte Count Increased MetaADEDB
Csf Neutrophil Count Increased MetaADEDB
Cutaneous Ulcer MetaADEDB
Cytomegalovirus Chorioretinitis MetaADEDB
Cytomegalovirus Colitis MetaADEDB
Cytomegalovirus Viraemia MetaADEDB
Dehydration MetaADEDB
Dementia Alzheimer Type MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Diabetes Insipidus MetaADEDB
Diarrhea MetaADEDB
Disease Of Liver MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Drowsiness MetaADEDB
Duodenal Scarring MetaADEDB
Electrocardiogram Change MetaADEDB
Encephalitis Allergic MetaADEDB
Enterocolitis MetaADEDB
Enterocolitis Bacterial MetaADEDB
Enterocolitis Infectious MetaADEDB
Eosinophil Count Increased MetaADEDB
Eosinophil Percentage Increased MetaADEDB
Epilepsy MetaADEDB
Erosive Gastritis MetaADEDB
Eruption MetaADEDB
Escherichia Infection MetaADEDB
Excess Potassium MetaADEDB
Eyelid Function Disorder MetaADEDB
Femoral Neck Fracture MetaADEDB
Fibrin D Dimer MetaADEDB
Fibrin Degradation Products Increased MetaADEDB
Food Poisoning MetaADEDB
Fungal Disease MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gangrene MetaADEDB
Gastric Ulcer Haemorrhage MetaADEDB
Gastroduodenitis MetaADEDB
Gastrointestinal Hypomotility MetaADEDB
Gastrointestinal Motility Disorder MetaADEDB
General Nutrition Disorder MetaADEDB
Gingival Hyperplasia MetaADEDB
Gingival Oedema MetaADEDB
Glucose Urine MetaADEDB
Grip Strength MetaADEDB
Haemangioma Of Liver MetaADEDB
Haemarthrosis MetaADEDB
Haematocrit Increased MetaADEDB
Haematoma Evacuation MetaADEDB
Haemorrhagic Hepatic Cyst MetaADEDB
Hepatic Congestion MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatitis C Antibody Positive MetaADEDB
Hernia Inguinal MetaADEDB
Histiocytosis Haematophagic MetaADEDB
Hyperalimentation MetaADEDB
Hyperventilation MetaADEDB
Hypoaesthesia MetaADEDB
Hypoalbuminaemia MetaADEDB
Hypochondriasis MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypoglycaemic Unconsciousness MetaADEDB
Hypokalaemia MetaADEDB
Hypomania MetaADEDB
Hypoproteinaemia MetaADEDB
Hypoxia MetaADEDB
Ild MetaADEDB
Immunosuppression MetaADEDB
Impetigo MetaADEDB
Increased Platelet Count MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection Upper Respiratory MetaADEDB
Intentional Self-Injury MetaADEDB
Intracardiac Mass MetaADEDB
Joint Arthroplasty MetaADEDB
Jra MetaADEDB
Labour Pain MetaADEDB
Leukopenia Neonatal MetaADEDB
Lip Erosion MetaADEDB
Lip Ulceration MetaADEDB
Liver Abscess MetaADEDB
Logorrhoea MetaADEDB
Lymphocyte Count Decreased MetaADEDB
Lymphocyte Percentage MetaADEDB
Lymphocyte Percentage Decreased MetaADEDB
Lymphocytes Decreased MetaADEDB
Malignant Neoplasm Progression MetaADEDB
Mania MetaADEDB
Middle Ear Inflammation MetaADEDB
Miosis MetaADEDB
Monocyte Percentage Decreased MetaADEDB
Mood Altered MetaADEDB
Mouth Ulcer MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Musculoskeletal Stiffness MetaADEDB
Mycobacterium Tuberculosis Infection MetaADEDB
Myringitis MetaADEDB
Nasopharyngitis MetaADEDB
Neoplasm Recurrence MetaADEDB
Nerve Block MetaADEDB
Neumonia MetaADEDB
Neuroleptic Malignant Syndrome MetaADEDB
Neurosis MetaADEDB
Neutrophil Count Decreased MetaADEDB
Nikolsky Sign MetaADEDB
Normal Delivery MetaADEDB
Nuclear Magnetic Resonance Imaging Abnormal MetaADEDB
Obstruction MetaADEDB
Oesophageal Candidiasis MetaADEDB
Oesophagitis Haemorrhagic MetaADEDB
Oliguria MetaADEDB
Oral Discomfort MetaADEDB
Oral Intake Reduced MetaADEDB
Oral Mucosa Erosion MetaADEDB
Oropharyngeal Pain MetaADEDB
Oropharyngeal Plaque MetaADEDB
Ovarian Cancer MetaADEDB
Palsies MetaADEDB
Pemphigus MetaADEDB
Peritonsillitis MetaADEDB
Persecutory Delusion MetaADEDB
Pertussis MetaADEDB
Pharyngeal Inflammation MetaADEDB
Phobia MetaADEDB
Photosensitive Rash MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pneumatosis Cystoides Intestinalis MetaADEDB
Pneumocystis Carinii Pneumonia MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Pneumothorax MetaADEDB
Poriomania MetaADEDB
Post Procedural Haematoma MetaADEDB
Proctalgia MetaADEDB
Protein Total Decreased MetaADEDB
Protein Total Increased MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Psychiatric Symptom MetaADEDB
Pulmonary Alveolar Haemorrhage MetaADEDB
Pyelonephritis MetaADEDB
Pyelonephritis Acute MetaADEDB
Pyoderma Gangrenosum MetaADEDB
Pyothorax MetaADEDB
Rectal Perforation MetaADEDB
Rectal Ulcer MetaADEDB
Red Cell Distribution Width Increased MetaADEDB
Reflux Esophagitis MetaADEDB
Renal Impairment MetaADEDB
Renal Tubular Disorder MetaADEDB
Respiratory Disorder Neonatal MetaADEDB
Respiratory Failure MetaADEDB
Retinal Bleeding MetaADEDB
Rhabdomyolysis MetaADEDB
Schizophrenia MetaADEDB
Scotoma MetaADEDB
Self Injurious Behaviour MetaADEDB
Self Mutilation MetaADEDB
Sick Sinus Syndrome MetaADEDB
Skin Erosion MetaADEDB
Skin Necrosis MetaADEDB
Speech Disorder MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Subcutaneous Haematoma MetaADEDB
Subdural Hygroma MetaADEDB
Subileus MetaADEDB
Sudden Cardiac Death MetaADEDB
Swollen Tongue MetaADEDB
Threatened Labour MetaADEDB
Tonsillitis MetaADEDB
Tooth Resorption MetaADEDB
Tuberculosis Of Genitourinary System MetaADEDB
Unresponsive To Stimuli MetaADEDB
Urine Ketone Body Present MetaADEDB
Urine Osmolarity Increased MetaADEDB
Urobilin Urine Present MetaADEDB
Uterine Cancer MetaADEDB
Verbal Abuse MetaADEDB
Vitrectomy MetaADEDB
Volvulus MetaADEDB

InAADR: Drug-Protein-ADRs database