InAADR

Drug Information

Drug Name: Acarbose (56180-94-0)
PubChem ID: 122172882
SMILES: C[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)OC3[C@H](OC([C@@H]([C@H]3O)O)O)CO)CO)O)O)N[C@H]4C=C([C@H]([C@@H]([C@H]4O)O)O)CO
InchiKey: XUFXOAAUWZOOIT-AKTIDKTPSA-N
Therapeutic Category: Enzyme Inhibitors, Glycoside Hydrolase Inhibitors, Hypoglycemic Agents

Computed Drug Properties

Molecular Weight (dalton): 645.608
LogP: -8.5645
Ring Count: 0
Hydrogen Bond Acceptor Count: 19
Hydrogen Bond Donor Count: 14
Total Polar Surface Area: 321.17

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Compartment Syndrome MetaADEDB
Abdominal Distension MetaADEDB
Abdominal Pain ADReCS
Abnormal Eeg MetaADEDB
Abnormal Faeces MetaADEDB
Abscess Bacterial MetaADEDB
Acantholysis MetaADEDB
Accidental Overdose MetaADEDB
Acetonaemia MetaADEDB
Acidosis MetaADEDB
Activated Partial Thromboplastin Time Shortened MetaADEDB
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Prerenal Failure MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenocarcinoma MetaADEDB
Adynamic Ileus MetaADEDB
Afib MetaADEDB
Agranulocytoses MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcoholic Cirrhosis MetaADEDB
Alcoholic Liver Disease MetaADEDB
Allergic Dermatitis MetaADEDB
Allergic Oedema MetaADEDB
Allergic Vasculitis MetaADEDB
Altered State Of Consciousness MetaADEDB
Amyloidosis MetaADEDB
Anaemia Hypochromic MetaADEDB
Anaesthesia MetaADEDB
Anal Abscess MetaADEDB
Androgen Deficiency MetaADEDB
Angina MetaADEDB
Angina Unstable MetaADEDB
Angioedema MetaADEDB
Anhedonia MetaADEDB
Anorectal Disorder MetaADEDB
Anorexia MetaADEDB
Anterior Chamber Inflammation MetaADEDB
Anti-Insulin Antibody MetaADEDB
Anti-Insulin Antibody Positive MetaADEDB
Antinuclear Antibody MetaADEDB
Aortic Occlusion MetaADEDB
Apathy MetaADEDB
Arterial Haemorrhage MetaADEDB
Arterial Occlusive Disease MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthritis Bacterial MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Ataxia MetaADEDB
Atelectasis MetaADEDB
Atrioventricular Block Complete MetaADEDB
Atrophy Of Skin MetaADEDB
Autonomic Neuropathy MetaADEDB
Bacillus Infection MetaADEDB
Benign Prostatic Hyperplasia MetaADEDB
Bezoar MetaADEDB
Bile Duct Obstruction MetaADEDB
Biliary Dilatation MetaADEDB
Bladder Neoplasm MetaADEDB
Bladder Retention MetaADEDB
Blast Cell Count Increased MetaADEDB
Bleeding Gums MetaADEDB
Bleeding Hemorrhoids MetaADEDB
Blood 25-Hydroxycholecalciferol Decreased MetaADEDB
Blood Albumin Abnormal MetaADEDB
Blood Albumin Increased MetaADEDB
Blood Alcohol Increased MetaADEDB
Blood Bilirubin Increased MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatine Phosphokinase Mb Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Glucose Abnormal MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Glucose Fluctuation MetaADEDB
Blood Immunoglobulin A Increased MetaADEDB
Blood Ketone Body MetaADEDB
Blood Phosphorus Decreased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Inadequately Controlled MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Sodium Increased MetaADEDB
Blood Uric Acid MetaADEDB
Blood Uric Acid Abnormal MetaADEDB
Bone Marrow Depression MetaADEDB
Bradyarrhythmia MetaADEDB
Brain Natriuretic Peptide Increased MetaADEDB
Brain Stem Infarction MetaADEDB
Brain Stem Ischaemia MetaADEDB
Breast Abscess MetaADEDB
Bronchial Infection MetaADEDB
Bronchopneumonia MetaADEDB
Bullous Lung Disease MetaADEDB
Bundle Branch Block Left MetaADEDB
Bundle Branch Block Right MetaADEDB
C-Reactive Protein Abnormal MetaADEDB
Calculus Urinary MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Fibrillation MetaADEDB
Cardiac Index Decreased MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Murmur MetaADEDB
Cardiac Operation MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardioactive Drug Level Increased MetaADEDB
Cardiomyopathy MetaADEDB
Cardiovascular Diseases MetaADEDB
Carotid Arteriosclerosis MetaADEDB
Carotid Artery Stenosis MetaADEDB
Carotidynia MetaADEDB
Cerebral Infarct MetaADEDB
Chromaturia MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Respiratory Failure MetaADEDB
Colitis Pseudomembranous MetaADEDB
Colpitis MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Congestive Cardiomyopathy MetaADEDB
Cor Pulmonale Chronic MetaADEDB
Coronary Angioplasty MetaADEDB
Coronary Artery Occlusion MetaADEDB
Coronary Artery Reocclusion MetaADEDB
Coronary Artery Restenosis MetaADEDB
Coronary Artery Stenosis MetaADEDB
Cutaneous Vasculitis MetaADEDB
Cytolytic Hepatitis ADReCS
Demyelination MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitides MetaADEDB
Dermatitis ADReCS
Dermatitis Exfoliative MetaADEDB
Dermatomyositis MetaADEDB
Diabetes MetaADEDB
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetes Mellitus Insulin-Dependent MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diabetic Acidosis MetaADEDB
Diabetic Gastroparesis MetaADEDB
Diabetic Nephropathy MetaADEDB
Diabetic Neuropathy MetaADEDB
Diabetic Retinopathy MetaADEDB
Dialysis MetaADEDB
Diaphragmatic Hernia MetaADEDB
Diarrhoea ADReCS
Diffuse Large B-Cell Lymphoma MetaADEDB
Disease Of Liver MetaADEDB
Disease Progression MetaADEDB
Disorder Retinal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Duodenal Ulcer MetaADEDB
Dyschezia MetaADEDB
Dyspepsia ADReCS
Early Satiety MetaADEDB
Ecchymoses MetaADEDB
Economic Problem MetaADEDB
Ectopic Pregnancies MetaADEDB
Eczema MetaADEDB
Edema Extremities MetaADEDB
Electrocardiogram Poor R-Wave Progression MetaADEDB
Electrocardiogram Qt Corrected Interval Shortened MetaADEDB
Electrocardiogram Repolarisation Abnormality MetaADEDB
Electromechanical Dissociation MetaADEDB
Elevated Prostate Specific Antigen MetaADEDB
Elevated Triglycerides MetaADEDB
Embolism MetaADEDB
Emesis MetaADEDB
Endometrial Cancer MetaADEDB
Endoscopy MetaADEDB
Energy Increased MetaADEDB
Eosinophil Count Increased MetaADEDB
Epidural Hematoma MetaADEDB
Erythema ADReCS
Escherichia Urinary Tract Infection MetaADEDB
Excess Potassium MetaADEDB
Excessive Sleepiness MetaADEDB
Exfoliative Rash MetaADEDB
Eye Operation MetaADEDB
Fear Of Death MetaADEDB
Febrile Bone Marrow Aplasia MetaADEDB
Feeling Of Despair MetaADEDB
Femoral Artery Occlusion MetaADEDB
Flatulence ADReCS
Floaters MetaADEDB
Food Allergy MetaADEDB
Foot Fracture MetaADEDB
Fractured Sacrum MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Cancer MetaADEDB
Gastroenteritis Bacterial MetaADEDB
Gastrointestinal Disorder ADReCS
Gastrointestinal Pain ADReCS
Gastrointestinal Perforation MetaADEDB
Gastrointestinal Symptom Nos SIDER
General Physical Health Deterioration MetaADEDB
Generalised Erythema MetaADEDB
Glomerulonephritis Rapidly Progressive MetaADEDB
Glomus Tumour MetaADEDB
Glucose Intolerance MetaADEDB
Glycosylated Haemoglobin Increased MetaADEDB
Gout MetaADEDB
Haematoma MetaADEDB
Haemorrhage Rectum MetaADEDB
Haemorrhagic Cerebral Infarction MetaADEDB
Haemothorax MetaADEDB
Head Deformity MetaADEDB
Heart Attack MetaADEDB
Heart Injury MetaADEDB
Heart Valve Calcification MetaADEDB
Hematoma Subdural MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Fibrosis MetaADEDB
Hepatic Function Abnormal ADReCS
Hepatitis ADReCS
Hepatitis Acute MetaADEDB
Hepatitis Fulminant ADReCS
Hepatocellular Injury ADReCS
Herpes Pharyngitis MetaADEDB
Herpes Virus Infection MetaADEDB
Hospitalisation MetaADEDB
Hyperalimentation MetaADEDB
Hypergammaglobulinaemia MetaADEDB
Hypermetropia MetaADEDB
Hyperosmolar State MetaADEDB
Hyperphosphataemia MetaADEDB
Hyperproteinaemia MetaADEDB
Hypertonia MetaADEDB
Hypocoagulable State MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypoglycaemic Encephalopathy MetaADEDB
Hypoproteinaemia MetaADEDB
Hypoxic Encephalopathy MetaADEDB
Ild MetaADEDB
Ileus ADReCS
Immobilisation Prolonged MetaADEDB
Impaired Fasting Glucose MetaADEDB
Inadequate Diet MetaADEDB
Induration MetaADEDB
Infantile Spasms MetaADEDB
Infected Skin Ulcer MetaADEDB
Inflammatory Myofibroblastic Tumour MetaADEDB
Injection Site Inflammation MetaADEDB
Injection Site Urticaria MetaADEDB
Insulin-Requiring Type 2 Diabetes Mellitus MetaADEDB
Intestinal Cyst MetaADEDB
Intestinal Haemorrhage MetaADEDB
Intestinal Hypomotility MetaADEDB
Intestinal Obstruction MetaADEDB
Intra-abdominal haematoma MetaADEDB
Intra-Abdominal Haemorrhage MetaADEDB
Iritis MetaADEDB
Ischaemia MetaADEDB
Ischaemic Cardiomyopathy MetaADEDB
Jaundice ADReCS
Joint Sprain MetaADEDB
Kaposi Sarcoma MetaADEDB
Kidney Enlargement MetaADEDB
Kidney Failure MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Leptospirosis MetaADEDB
Lichenoid Keratosis MetaADEDB
Life Expectancy Shortened MetaADEDB
Lip Haemorrhage MetaADEDB
Liver Failure Acute MetaADEDB
Liver Function Test Abnormal ADReCS
Liver Injury ADReCS
Localised Infection MetaADEDB
Localised Oedema MetaADEDB
Loss Of Weight MetaADEDB
Lung Adenocarcinoma Metastatic MetaADEDB
Lung Edema MetaADEDB
Lung Infection MetaADEDB
Lung Infection Pseudomonal MetaADEDB
Lung Neoplasm Malignant MetaADEDB
Macroglossia MetaADEDB
Macular Oedema MetaADEDB
Malignant Melanoma Of Sites Other Than Skin MetaADEDB
Malignant Tumour Excision MetaADEDB
Markedly Reduced Dietary Intake MetaADEDB
Mastectomy MetaADEDB
Mechanical Ventilation MetaADEDB
Meningorrhagia MetaADEDB
Menopausal Disorder MetaADEDB
Mental Disorder MetaADEDB
Metabolic Disorder MetaADEDB
Motor Retardation MetaADEDB
Mouth Breathing MetaADEDB
Mycobacterium Tuberculosis Infection MetaADEDB
Myeloid Maturation Arrest MetaADEDB
Myelopathy MetaADEDB
Nausea ADReCS
Near Syncope MetaADEDB
Necrosis Of Artery MetaADEDB
Neoplasia MetaADEDB
Nephritis Allergic MetaADEDB
Nephritis Autoimmune MetaADEDB
Neurodegenerative Disorder MetaADEDB
Neurogenic Shock MetaADEDB
Neurological Examination Abnormal MetaADEDB
Nicotine Dependence MetaADEDB
Normochromic Normocytic Anaemia MetaADEDB
Obstructive Uropathy MetaADEDB
Oedema ADReCS
Oral Herpes MetaADEDB
Orchitis MetaADEDB
Ovarian Cyst MetaADEDB
Pain ADReCS
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Palpitation MetaADEDB
Pancreatic Enzymes Increased MetaADEDB
Paraparesis MetaADEDB
Parkinson MetaADEDB
Pedal Pulse Absent MetaADEDB
Pemphigus MetaADEDB
Pericardial Effusion MetaADEDB
Peripheral Arterial Occlusive Disease MetaADEDB
Peripheral Embolism MetaADEDB
Peroneal Nerve Injury MetaADEDB
Pitting Oedema MetaADEDB
Pleural Effusion MetaADEDB
Pneumatosis ADReCS
Pneumatosis Cystoides Intestinalis MetaADEDB
Pneumocystis Jiroveci Infection MetaADEDB
Poor Peripheral Circulation MetaADEDB
Portal Venous Gas MetaADEDB
Productive Cough MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus Generalised MetaADEDB
Pseudo Lymphoma MetaADEDB
Psychiatric Symptom MetaADEDB
Pulmonary Arrest MetaADEDB
Pulmonary Valve Incompetence MetaADEDB
Puncture Site Haemorrhage MetaADEDB
Quality Of Life Decreased MetaADEDB
Rash ADReCS
Renal Impairment MetaADEDB
Renal Tubular Disorder MetaADEDB
Respiratory Tract Congestion MetaADEDB
Retinal Artery Occlusion MetaADEDB
Retinal Bleeding MetaADEDB
Retrograde Amnesia MetaADEDB
Rhabdomyolysis MetaADEDB
Rhinitis MetaADEDB
Right Heart Failure MetaADEDB
Right Ventricular Systolic Pressure Increased MetaADEDB
Schizophrenia Paranoid Type MetaADEDB
Sepsis Syndrome MetaADEDB
Septic Shock MetaADEDB
Serum Ferritin Decreased MetaADEDB
Shock ADReCS
Shock Haemorrhagic MetaADEDB
Shock Hypoglycaemic ADReCS
Similar Reaction On Previous Exposure To Drug MetaADEDB
Skeletal Injury MetaADEDB
Snoring MetaADEDB
Stent Occlusion MetaADEDB
Stent Related Infection MetaADEDB
Sternal Fracture MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Stress Fracture MetaADEDB
Subcutaneous Haematoma MetaADEDB
Subileus ADReCS
Sudden Cardiac Death MetaADEDB
Surgery MetaADEDB
Testicular Mass MetaADEDB
Thrombocytopenia ADReCS
Thrombophlebitis MetaADEDB
Thrombotic Stroke MetaADEDB
Tracheobronchitis MetaADEDB
Traumatic Haematoma MetaADEDB
Ulnar Neuritis MetaADEDB
Unevaluable Event MetaADEDB
Upper Gastrointestinal Bleeding MetaADEDB
Urticaria ADReCS
Vascular Graft MetaADEDB
Vertebral Injury MetaADEDB
Vitrectomy MetaADEDB
Vitreous Haemorrhage MetaADEDB
Vocal Cord Paralysis MetaADEDB
Vomiting ADReCS
Vomiting Psychogenic MetaADEDB
Weight Gain MetaADEDB

InAADR: Drug-Protein-ADRs database