| Drug Name: | Diethylstilbestrol (56-53-1) |
|---|---|
| PubChem ID: | 448537 |
| SMILES: | CC/C(=C(/CC)C1=CC=C(C=C1)O)/C2=CC=C(C=C2)O |
| InchiKey: | RGLYKWWBQGJZGM-ISLYRVAYSA-N |
| Therapeutic Category: | Carcinogens, Estrogens, Hormones, Noxae |
| Molecular Weight (dalton) | : | 268.356 |
| LogP | : | 4.8286 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 2 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 40.46 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Rash | Muscarinic acetylcholine receptor M2 (P08172) | Not Available | Large-scale prediction and testing of drug activity on side-effect targets |
| Unscheduled Dna Synthesis (Uds) | Glutathione peroxidase 1 (P07203) | DES can potentially form phenoxyradical intermediates by a peroxidase-mediated reaction@which leads to unscheduled DNA synthesis (UDS) in Syrian hamster embryo cells. [ ADR Type 2 ] | Dependence on exogenous metabolic activation for induction of unscheduled DNA synthesis in Syrian hamster embryo cells by diethylstilbestrol and related compounds |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category