Drug Name: | Nicardipine (55985-32-5) |
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PubChem ID: | 4474 |
SMILES: | CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC |
InchiKey: | ZBBHBTPTTSWHBA-UHFFFAOYSA-N |
Therapeutic Category: | Antihypertensive Agents, Calcium Channel Blockers, Cardiovascular Agents, Membrane Transport Modulators, Vasodilator Agents |
Molecular Weight (dalton) | : | 479.533 |
LogP | : | 3.6778 |
Ring Count | : | 2 |
Hydrogen Bond Acceptor Count | : | 8 |
Hydrogen Bond Donor Count | : | 1 |
Total Polar Surface Area | : | 111.01 |
This panel provides information on interacting drugs and their ADRs along with references
Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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This panel provides drug-protein interaction and their ADRs along with references
Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
Food | Toxicity | Reference |
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Grapefruit Juice | Hypotension | Food–drug interaction: grapefruit juice augments drug bioavailabilityFmechanism, extent and relevance |
Grapefruit Juice | Tachycardia | Food–drug interaction: grapefruit juice augments drug bioavailabilityFmechanism, extent and relevance |
This panel provides information on metabolites and their ADRs along with references
Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category