Drug Name: | Busulfan (55-98-1) |
---|---|
PubChem ID: | 2478 |
SMILES: | CS(=O)(=O)OCCCCOS(=O)(=O)C |
InchiKey: | COVZYZSDYWQREU-UHFFFAOYSA-N |
Therapeutic Category: | Alkylating Agents, Antineoplastic Agents, Immunologic Factors, Immunosuppressive Agents, Myeloablative Agonists, Noxae |
Molecular Weight (dalton) | : | 246.306 |
LogP | : | -0.281 |
Ring Count | : | 0 |
Hydrogen Bond Acceptor Count | : | 6 |
Hydrogen Bond Donor Count | : | 0 |
Total Polar Surface Area | : | 86.74 |
This panel provides information on interacting drugs and their ADRs along with references
Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
---|---|---|---|---|
Thioguanine (154-42-7) | Hepatic Nodular Hyperplasia | Synergistic | Not known | Oesophageal varices associated with busulphan-thioguanine combination therapy for chronic myeloid leukaemia |
This panel provides drug-protein interaction and their ADRs along with references
Toxicity | Interacting Protein | Mechanism | Reference |
---|
This panel provides drug-food interactions and their ADRs along with references
Food | Toxicity | Reference |
---|
This panel provides information on metabolites and their ADRs along with references
Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
---|
This panel provides information on drug category