InAADR

Drug Information

Drug Name: zuclopenthixol (53772-83-1)
PubChem ID: 5311507
SMILES: C1CN(CCN1CC/C=C2/C3=CC=CC=C3SC4=C2C=C(C=C4)Cl)CCO
InchiKey: WFPIAZLQTJBIFN-DVZOWYKESA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 400.975
LogP: 4.2363
Ring Count: 2
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 26.71

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Akathisia D(2) dopamine receptor (P14416) Antipsychotic response (D2@ D3@ D4)@antipsychotic-induced tardive dyskinesia (D3)@antipsychotic-induced acute akathisia (D3). [ ADR Type 2 ] Pharmacogenetics and antipsychotic drugs
Akathisia D(3) dopamine receptor (P35462) Antipsychotic response (D2@ D3@ D4)@antipsychotic-induced tardive dyskinesia (D3)@antipsychotic-induced acute akathisia (D3) [ ADR Type 2 ] Pharmacogenetics and antipsychotic drugs
Akathisia D(4) dopamine receptor (P21917) Antipsychotic response (D2@ D3@ D4)@antipsychotic-induced tardive dyskinesia (D3)@antipsychotic-induced acute akathisia (D3) [ ADR Type 2 ] Pharmacogenetics and antipsychotic drugs
Tardive Dyskinesia D(2) dopamine receptor (P14416) Antipsychotic response (D2@ D3@ D4)@antipsychotic-induced tardive dyskinesia (D3)@antipsychotic-induced acute akathisia (D3). [ ADR Type 2 ] Pharmacogenetics and antipsychotic drugs
Tardive Dyskinesia D(3) dopamine receptor (P35462) Antipsychotic response (D2@ D3@ D4)@antipsychotic-induced tardive dyskinesia (D3)@antipsychotic-induced acute akathisia (D3) [ ADR Type 2 ] Pharmacogenetics and antipsychotic drugs
Tardive Dyskinesia D(4) dopamine receptor (P21917) Antipsychotic response (D2@ D3@ D4)@antipsychotic-induced tardive dyskinesia (D3)@antipsychotic-induced acute akathisia (D3) [ ADR Type 2 ] Pharmacogenetics and antipsychotic drugs

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Rigidity MetaADEDB
Abnormal Behaviour MetaADEDB
Abortion Induced MetaADEDB
Accelerated Hypertension MetaADEDB
Accidental Exposure MetaADEDB
Acute Brain Syndrome MetaADEDB
Addison Disease MetaADEDB
Adrenal Neoplasm MetaADEDB
Adynamic Ileus MetaADEDB
Affect Lability MetaADEDB
Affective Disorder MetaADEDB
Aggression MetaADEDB
Agitated MetaADEDB
Agoraphobia MetaADEDB
Alcohol Consumption MetaADEDB
Allergic Vasculitis MetaADEDB
Altered State Of Consciousness MetaADEDB
Amenorrhea MetaADEDB
Anorexia MetaADEDB
Anticonvulsant Drug Level Increased MetaADEDB
Antipsychotic Drug Level Below Therapeutic MetaADEDB
Antisocial Behaviour MetaADEDB
Anuria MetaADEDB
Anxiety MetaADEDB
Apathy MetaADEDB
Aplasia Pure Red Cell MetaADEDB
Aptyalism MetaADEDB
Arrhythmia MetaADEDB
Asthenia MetaADEDB
Aura MetaADEDB
Binge Eating MetaADEDB
Bladder Retention MetaADEDB
Blood Chloride Decreased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Sodium MetaADEDB
Blood Thyroid Stimulating Hormone Increased MetaADEDB
Body Mass Index Increased MetaADEDB
Body Temperature MetaADEDB
Body Temperature Increased MetaADEDB
Bone Marrow Toxicity MetaADEDB
Brain Damage MetaADEDB
Breast Cancer MetaADEDB
Bronchitis MetaADEDB
Bronchopneumonia MetaADEDB
Bruxism MetaADEDB
Cardiac Hypertrophy MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiomyopathy MetaADEDB
Cardiopulmonary Failure MetaADEDB
Cartilage Development Disorder MetaADEDB
Catatonia MetaADEDB
Cerebellar Syndrome MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebral Haemorrhage MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest Infection MetaADEDB
Chest Pain MetaADEDB
Cholinergic Syndrome MetaADEDB
Cognitive Disorder MetaADEDB
Coma MetaADEDB
Confabulation MetaADEDB
Congenital Diaphragmatic Hernia MetaADEDB
Congenital Heart Disease MetaADEDB
Conjunctival Hyperaemia MetaADEDB
Constipated MetaADEDB
Cough MetaADEDB
Cystic Lymphangioma MetaADEDB
Cytolytic Hepatitis MetaADEDB
Decreased Activity MetaADEDB
Decreased Interest MetaADEDB
Delusion MetaADEDB
Delusion Of Grandeur MetaADEDB
Delusional Disorder Persecutory Type MetaADEDB
Demyelination MetaADEDB
Depressed Mood MetaADEDB
Disorder Renal MetaADEDB
Disturbance In Attention MetaADEDB
Disturbance In Social Behaviour MetaADEDB
Drowsiness MetaADEDB
Drug Addict MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Interaction MetaADEDB
Dysphoria MetaADEDB
Dysthymic Disorder MetaADEDB
Echolalia MetaADEDB
Eczema MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Electrocardiogram St-T Change MetaADEDB
Embolism Pulmonary MetaADEDB
Emesis MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Euphoric Mood MetaADEDB
Excessive Salivation MetaADEDB
Excessive Thirst MetaADEDB
Extrasystoles MetaADEDB
Extrasystoles Ventricular MetaADEDB
Fanconi Syndrome MetaADEDB
Fatigue MetaADEDB
Fear Of Death MetaADEDB
Flight Of Ideas MetaADEDB
Galactorrhea MetaADEDB
Gastrointestinal Obstruction MetaADEDB
General Physical Health Deterioration MetaADEDB
Granulocytes Abnormal MetaADEDB
Haemorrhage Subcutaneous MetaADEDB
Hallucinations Mixed MetaADEDB
Head Titubation MetaADEDB
Heart Rate Increased MetaADEDB
Heart Sounds Abnormal MetaADEDB
Hemianopia MetaADEDB
Hepatocellular Injury MetaADEDB
High Blood Pressure MetaADEDB
High Density Lipoprotein Decreased MetaADEDB
Hygroma Colli MetaADEDB
Hyperprolactinaemia MetaADEDB
Hyperreflexia MetaADEDB
Hyperventilation MetaADEDB
Hypokinesia MetaADEDB
Hypomania MetaADEDB
Hypophosphataemia MetaADEDB
Impaired Self-Care MetaADEDB
Incontinence MetaADEDB
Infection Viral MetaADEDB
Intestinal Congestion MetaADEDB
Intestinal Obstruction MetaADEDB
Laceration MetaADEDB
Lacrimation Increased MetaADEDB
Laryngeal Haemorrhage MetaADEDB
Leg Amputation MetaADEDB
Lethargy MetaADEDB
Leucopenia MetaADEDB
Leukopenia Neonatal MetaADEDB
Lip Exfoliation MetaADEDB
Logorrhoea MetaADEDB
Loss Of Employment MetaADEDB
Loss Of Weight MetaADEDB
Lupus-Like Syndrome MetaADEDB
Mental Impairment MetaADEDB
Metabolic Disorder MetaADEDB
Metabolic Syndrome MetaADEDB
Metastases To Lung MetaADEDB
Metastases To Neck MetaADEDB
Miosis MetaADEDB
Motor Dysfunction MetaADEDB
Multiple Congenital Abnormalities MetaADEDB
Multiple Drug Overdose MetaADEDB
Mumps MetaADEDB
Muscle Disorder MetaADEDB
Nephrogenic Diabetes Insipidus MetaADEDB
Neuroleptic Malignant Syndrome MetaADEDB
Neutrophil Count Decreased MetaADEDB
Oropharyngeal Pain MetaADEDB
Osteolysis MetaADEDB
Overdose MetaADEDB
Overweight MetaADEDB
Pericarditis MetaADEDB
Persecutory Delusion MetaADEDB
Personality Change MetaADEDB
Personality Disorder MetaADEDB
Pharyngolaryngeal Pain MetaADEDB
Placental Disorder MetaADEDB
Poor Quality Sleep MetaADEDB
Psychosexual Disorder MetaADEDB
Pulmonary Arrest MetaADEDB
Pyramidal Tract Syndrome MetaADEDB
Qrs Axis Abnormal MetaADEDB
Quality Of Life Decreased MetaADEDB
Regurgitation MetaADEDB
Renal Cyst MetaADEDB
Renal Tubular Disorder MetaADEDB
Respiratory Rate Increased MetaADEDB
Salivary Gland Calculus MetaADEDB
Schizophrenia MetaADEDB
Schizophrenia Paranoid Type MetaADEDB
Self-Injurious Ideation MetaADEDB
Shoulder Pain MetaADEDB
Sinus Bradycardia MetaADEDB
Somatic Delusion MetaADEDB
Speech Disorder MetaADEDB
Stereotypy MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Stress MetaADEDB
Sudden Death MetaADEDB
Tachyphrenia MetaADEDB
Tearfulness MetaADEDB
Theft MetaADEDB
Therapeutic Response Decreased MetaADEDB
Thyroxine Free Decreased MetaADEDB
Tongue Spasm MetaADEDB
Tonsillar Hypertrophy MetaADEDB
Tonsillitis MetaADEDB
Tooth Disease MetaADEDB
Treatment Noncompliance MetaADEDB
Troponin I Increased MetaADEDB
Troponin Increased MetaADEDB
Urine Analysis Abnormal MetaADEDB
Walking Aid User MetaADEDB
Waxy Flexibility MetaADEDB
Weight Decrease Neonatal MetaADEDB
White Blood Cell Disorder MetaADEDB
Withdrawal Syndrome MetaADEDB

InAADR: Drug-Protein-ADRs database