Drug Name: | Propoxyphene (469-62-5) |
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PubChem ID: | 10100 |
SMILES: | CCC(=O)O[C@](CC1=CC=CC=C1)(C2=CC=CC=C2)[C@H](C)CN(C)C |
InchiKey: | XLMALTXPSGQGBX-GCJKJVERSA-N |
Therapeutic Category: |
Molecular Weight (dalton) | : | 339.479 |
LogP | : | 4.2755 |
Ring Count | : | 2 |
Hydrogen Bond Acceptor Count | : | 3 |
Hydrogen Bond Donor Count | : | 0 |
Total Polar Surface Area | : | 29.54 |
This panel provides information on interacting drugs and their ADRs along with references
Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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Carbamazepine (298-46-4) | Dizziness | Synergistic | Uncertain. It is suggested that dextropropoxyphene inhibits the metabolism of carbamazepine by the liver, leading to its accumulation in the body. | Influence of dextropropoxyphene on steady state serum levels and protein binding of three anti-epileptic drugs in man |
Orphenadrine (83-98-7) | Tremors | Antagonistic | Not Understood | Drug interaction? Orphenadrine with propoxyphene |
This panel provides drug-protein interaction and their ADRs along with references
Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category