| Drug Name: | Diazepam (439-14-5) |
|---|---|
| PubChem ID: | 3016 |
| SMILES: | CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3 |
| InchiKey: | AAOVKJBEBIDNHE-UHFFFAOYSA-N |
| Therapeutic Category: | Adjuvants, Anesthetics, Anti-Anxiety Agents, Anticonvulsants, Antiemetics, Autonomic Agents, Central Nervous System Agents, Central Nervous System Depressants, GABA Agents, GABA Modulators, Gastrointestinal Agents, Hypnotics and Sedatives, Muscle Relaxants, Neuromuscular Agents, Neurotransmitter Agents, Peripheral Nervous System Agents, Psychotropic Drugs, Tranquilizing Agents |
| Molecular Weight (dalton) | : | 284.746 |
| LogP | : | 3.1538 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 2 |
| Hydrogen Bond Donor Count | : | 0 |
| Total Polar Surface Area | : | 32.67 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Levodopa (59-92-7) | Parkinson Disease | Antagonistic | Not understood | Review of 12 months' treatment with L-dopa in Parkinson's disease, with remarks on unusual side effects |
This panel provides drug-protein interaction and their ADRs along with references
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|---|---|
| Grapefruit Juice | Cns Depression | Food–drug interaction: grapefruit juice augments drug bioavailabilityFmechanism, extent and relevance |
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|---|---|---|---|
| N-desmethyl-diazepam | Adverse Autonomic Nervous Symptoms | Plasma concentrations of diazepam and of its metabolite N-desmethyldiazepam in relation to anxiolytic effect |
This panel provides information on drug category