InAADR

Drug Information

Drug Name: Protriptyline (438-60-8)
PubChem ID: 4976
SMILES: CNCCCC1C2=CC=CC=C2C=CC3=CC=CC=C13
InchiKey: BWPIARFWQZKAIA-UHFFFAOYSA-N
Therapeutic Category: Adrenergic Agents, Adrenergic Uptake Inhibitors, Antidepressive Agents, Central Nervous System Agents, Membrane Transport Modulators, Neurotransmitter Agents, Neurotransmitter Uptake Inhibitors, Psychotropic Drugs

Computed Drug Properties

Molecular Weight (dalton): 263.384
LogP: 4.3019
Ring Count: 2
Hydrogen Bond Acceptor Count: 1
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 12.03

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Cramp ADReCS
Abdominal Cramp SIDER
Abdominal Pain ADReCS
Accommodation Disorder ADReCS
Acute Coronary Syndrome ADReCS
Addiction SIDER
Adenitis SIDER
Agitation ADReCS
Agranulocytosis ADReCS
Alopecia ADReCS
Anorexia ADReCS
Anxiety ADReCS
Arrhythmia ADReCS
Asthenia ADReCS
Ataxia ADReCS
Atrioventricular Block ADReCS
Bipolar Disorder MetaADEDB
Black Hairy Tongue SIDER
Block Heart SIDER
Blood Glucose Abnormal ADReCS
Body Temperature Increased ADReCS
Bone Marrow Depression SIDER
Bone Marrow Failure ADReCS
Breast Enlargement ADReCS
Catalepsy MetaADEDB
Cataplexy MetaADEDB
Cerebrovascular Accident ADReCS
Confusional State ADReCS
Constipation ADReCS
Convulsion ADReCS
Coordination Abnormal ADReCS
Cramp Muscle SIDER
Decreased Appetite ADReCS
Delusion ADReCS
Dependence ADReCS
Depressive Disorder MetaADEDB
Dermatitis ADReCS
Diarrhoea ADReCS
Discomfort ADReCS
Disorientation ADReCS
Disturbance In Sexual Arousal ADReCS
Dizziness ADReCS
Drowsiness SIDER
Drug Dependence ADReCS
Drug Fever ADReCS
Dry Mouth ADReCS
Dysgeusia ADReCS
Dyspepsia ADReCS
Electroencephalogram Abnormal ADReCS
Eosinophilia ADReCS
Epigastric Distress SIDER
Epilepsy MetaADEDB
Erectile Dysfunction ADReCS
Extrapyramidal Disorder ADReCS
Extrapyramidal Symptoms SIDER
Fatigue ADReCS
Feeling Abnormal ADReCS
Flushing ADReCS
Galactorrhoea ADReCS
Gastrointestinal Pain ADReCS
Generalised Oedema ADReCS
Gynaecomastia ADReCS
Hallucination ADReCS
Headache ADReCS
Hepatic Function Abnormal ADReCS
Hepatomegaly ADReCS
Hyperhidrosis ADReCS
Hyperpyrexia ADReCS
Hypertension ADReCS
Hypertrophy ADReCS
Hypoaesthesia ADReCS
Hypomania ADReCS
Hypotension ADReCS
Hypotension Orthostatic MetaADEDB
Ileus ADReCS
Ileus Paralytic ADReCS
Ill-Defined Disorder ADReCS
Impotence ADReCS
Inappropriate Antidiuretic Hormone Secretion ADReCS
Infarction ADReCS
Insomnia ADReCS
Intraocular Pressure Increased ADReCS
Jaundice ADReCS
Leukopenia ADReCS
Libido Decreased ADReCS
Libido Disorder ADReCS
Lymphadenitis ADReCS
Malaise ADReCS
Micturition Disorder ADReCS
Muscle Spasms ADReCS
Mydriasis ADReCS
Myocardial Infarction ADReCS
Nausea ADReCS
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Nightmare ADReCS
Nocturia ADReCS
Numbness SIDER
Oedema ADReCS
Orthostatic Hypotension ADReCS
Palpitations ADReCS
Pancytopenia ADReCS
Panic Disorder ADReCS
Panic Reaction ADReCS
Paraesthesia ADReCS
Parotid Gland Enlargement ADReCS
Parotid Swelling SIDER
Peripheral Sensory Neuropathy ADReCS
Petechiae ADReCS
Photosensitivity Reaction ADReCS
Pollakiuria ADReCS
Product Taste Abnormal ADReCS
Pruritus ADReCS
Psychotic Disorder ADReCS
Purpura ADReCS
Rash ADReCS
Restlessness ADReCS
Seizures SIDER
Sensory Loss ADReCS
Somnambulism MetaADEDB
Somnolence ADReCS
Stomatitis ADReCS
Stroke ADReCS
Substance Withdrawal Syndrome MetaADEDB
Sweating SIDER
Swelling ADReCS
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Taste Peculiar SIDER
Testicular Swelling ADReCS
Thrombocytopenia ADReCS
Tingling Sensation SIDER
Tinnitus ADReCS
Tongue Discolouration ADReCS
Tongue Oedema ADReCS
Tremor ADReCS
Urinary Retention ADReCS
Urinary Tract Malformation ADReCS
Urticaria ADReCS
Vascular Purpura ADReCS
Ventricular Fibrillation MetaADEDB
Vision Blurred ADReCS
Vomiting ADReCS
Weakness SIDER
Weight Abnormal ADReCS
Weight Increased ADReCS
Xerostomia MetaADEDB

InAADR: Drug-Protein-ADRs database