InAADR

Drug Information

Drug Name: Trimebutine (39133-31-8)
PubChem ID: 5573
SMILES: CCC(COC(=O)C1=CC(=C(C(=C1)OC)OC)OC)(C2=CC=CC=C2)N(C)C
InchiKey: LORDFXWUHHSAQU-UHFFFAOYSA-N
Therapeutic Category: Autonomic Agents, Gastrointestinal Agents, Parasympatholytics, Peripheral Nervous System Agents

Computed Drug Properties

Molecular Weight (dalton): 387.476
LogP: 3.7363
Ring Count: 2
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 57.23

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Adhesions MetaADEDB
Abdominal Distension MetaADEDB
Abdominal mass MetaADEDB
Abdominal Pain MetaADEDB
Abnormal Movements MetaADEDB
Abscess Intestinal MetaADEDB
Acidosis MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Pancreatitis MetaADEDB
Acute Prerenal Failure MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Adenocarcinoma MetaADEDB
Adhesion MetaADEDB
Adrenal Insufficiency MetaADEDB
Adynamic Ileus MetaADEDB
Afib MetaADEDB
Agranulocytoses MetaADEDB
Agraphia MetaADEDB
Alcohol Poisoning MetaADEDB
Alcoholic Liver Disease MetaADEDB
Alkalosis Hypochloraemic MetaADEDB
Allergic Dermatitis MetaADEDB
Altered State Of Consciousness MetaADEDB
Amentia MetaADEDB
Ammonia Increased MetaADEDB
Anaemia MetaADEDB
Anal Fissure MetaADEDB
Anal Stenosis MetaADEDB
Angiokeratoma MetaADEDB
Anorexia MetaADEDB
Anticholinergic Syndrome MetaADEDB
Anuria MetaADEDB
Aortic Dilatation MetaADEDB
Apathy MetaADEDB
Arrhythmia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Ascites MetaADEDB
Aspiration Pneumonia MetaADEDB
Asthenia MetaADEDB
Asthmatic Crisis MetaADEDB
Autonomic Instability MetaADEDB
Axonal Neuropathy MetaADEDB
Bacterial Sepsis MetaADEDB
Basophil Percentage Increased MetaADEDB
Benign Intracranial Hypertension MetaADEDB
Bile Duct Obstruction MetaADEDB
Bile Duct Stone MetaADEDB
Biliary Adenoma MetaADEDB
Binocular Eye Movement Disorder MetaADEDB
Bladder Inflammation MetaADEDB
Blood Aldosterone Increased MetaADEDB
Blood Cholinesterase Decreased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Decreased MetaADEDB
Blood Ethanol Increased MetaADEDB
Blood Fibrinogen Increased MetaADEDB
Blood Gastrin Increased MetaADEDB
Blood Ketone Body Increased MetaADEDB
Blood Ketone Body Present MetaADEDB
Blood Pressure Systolic Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Sodium Increased MetaADEDB
Blood Urea Increased MetaADEDB
Body Temperature Increased MetaADEDB
Bone Marrow Failure MetaADEDB
Bowel Sounds Abnormal MetaADEDB
Brain Natriuretic Peptide Increased MetaADEDB
Brain Stem Infarction MetaADEDB
Breast Oedema MetaADEDB
Breath Sounds MetaADEDB
Bronchial Infection MetaADEDB
Burn Oesophageal MetaADEDB
Bursitis MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cancer MetaADEDB
Candida Infection MetaADEDB
Carcinoid Syndrome MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Ischemia MetaADEDB
Cardiac Pacemaker Replacement MetaADEDB
Cardiac Tamponade MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cartilage Development Disorder MetaADEDB
Cell Death MetaADEDB
Cerebellar Syndrome MetaADEDB
Cerebral Calcification MetaADEDB
Cerebral Haemorrhage MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest Wall Cyst MetaADEDB
Cholangiolitis MetaADEDB
Cholecystitis MetaADEDB
Chronic Ulcerative Colitis MetaADEDB
Clonus MetaADEDB
Clumsiness MetaADEDB
Cmv Infection MetaADEDB
Colitis MetaADEDB
Colitis Collagenous MetaADEDB
Colonic Pseudo-Obstruction MetaADEDB
Colonoscopy MetaADEDB
Compression Fracture MetaADEDB
Concomitant Disease Progression MetaADEDB
Condition Aggravated MetaADEDB
Confabulation MetaADEDB
Constipated MetaADEDB
Contracture MetaADEDB
Coordination Abnormal MetaADEDB
Cryptogenic Organising Pneumonia MetaADEDB
Csf Neutrophil Count Increased MetaADEDB
Csf Neutrophil Count Positive MetaADEDB
Csf Pressure Increased MetaADEDB
Cyanosis MetaADEDB
Cystitis Escherichia MetaADEDB
Cytolytic Hepatitis MetaADEDB
Cytomegalovirus Test MetaADEDB
Dehydration MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitides MetaADEDB
Dermatitis Bullous MetaADEDB
Diarrhea MetaADEDB
Diplopia MetaADEDB
Disease Of Liver MetaADEDB
Disease Recurrence MetaADEDB
Disorder Lung MetaADEDB
Disseminated Tuberculosis MetaADEDB
Drowsiness MetaADEDB
Drug Abuser MetaADEDB
Drug Withdrawal Headache MetaADEDB
Duodenal Obstruction MetaADEDB
Duodenal Stenosis MetaADEDB
Duodenitis MetaADEDB
Dysphasia MetaADEDB
Eczema MetaADEDB
Electrocardiogram Qt Corrected Interval Prolonged MetaADEDB
Electrocardiogram St Segment Abnormal MetaADEDB
Electrocardiogram T Wave Amplitude Decreased MetaADEDB
Electrocardiogram T Wave Inversion MetaADEDB
Elevated Triglycerides MetaADEDB
Emesis MetaADEDB
Endocarditis Staphylococcal MetaADEDB
Enteritis MetaADEDB
Enteritis Infectious MetaADEDB
Enterobacter Infection MetaADEDB
Eosinophilic Pneumonia MetaADEDB
Epidermal Growth Factor Receptor Increased MetaADEDB
Erosive Oesophagitis MetaADEDB
Excessive Thirst MetaADEDB
Extrasystoles MetaADEDB
Febrile Bone Marrow Aplasia MetaADEDB
Femoral Neck Fracture MetaADEDB
Flatulence MetaADEDB
Foetal Arrhythmia MetaADEDB
Foetal Growth Retardation MetaADEDB
Foetal Heart Rate MetaADEDB
Gallbladder Cancer MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastrointestinal Toxicity MetaADEDB
General Physical Health Deterioration MetaADEDB
Globulinuria MetaADEDB
Glomerulonephritis MetaADEDB
Glossitis MetaADEDB
Granulocytosis MetaADEDB
Gum Neoplasm Malignant Stage Unspecified MetaADEDB
Haemangioma MetaADEDB
Haematemesis MetaADEDB
Haemodialysis MetaADEDB
Haemolytic Anaemia MetaADEDB
Haemorrhage Rectum MetaADEDB
Haemorrhoids MetaADEDB
Heart Sounds Abnormal MetaADEDB
Hematoma Subdural MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatitis MetaADEDB
Hepatitis C MetaADEDB
Hepatocellular Injury MetaADEDB
High Blood Pressure MetaADEDB
Histiocytosis Haematophagic MetaADEDB
Hyperchloraemia MetaADEDB
Hyperreflexia MetaADEDB
Hypokalaemia MetaADEDB
Hypotension Orthostatic MetaADEDB
Ild MetaADEDB
Ileal Stenosis MetaADEDB
Incontinence MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infusion Related Reaction MetaADEDB
Intervertebral Disc Calcification MetaADEDB
Intestinal Obstruction MetaADEDB
Intubation MetaADEDB
Jaundice Neonatal MetaADEDB
Jejunal Perforation MetaADEDB
Kidney Failure MetaADEDB
Lactate Pyruvate Ratio Increased MetaADEDB
Locked-In Syndrome MetaADEDB
Lung Abscess MetaADEDB
Lung Fibrosis MetaADEDB
Lymphangiopathy MetaADEDB
Lymphangiosis Carcinomatosa MetaADEDB
Lymphocyte Count Decreased MetaADEDB
Lymphocyte Percentage Decreased MetaADEDB
Megacolon MetaADEDB
Mental Disorder MetaADEDB
Metastases To Central Nervous System MetaADEDB
Metastases To Lymph Nodes MetaADEDB
Metastases To Peritoneum MetaADEDB
Muscle Enzyme MetaADEDB
Nasopharyngitis MetaADEDB
Neurosis MetaADEDB
No Therapeutic Response MetaADEDB
Non-Small Cell Lung Cancer MetaADEDB
Nystagmus MetaADEDB
Obstruction MetaADEDB
Oestrogen Receptor Assay Positive MetaADEDB
Oliguria MetaADEDB
Optic Disc Edema MetaADEDB
Oral Fungal Infection MetaADEDB
Oropharyngeal Discomfort MetaADEDB
Pelvic Fluid Collection MetaADEDB
Pericarditis MetaADEDB
Peripheral Ischaemia MetaADEDB
Peripheral Sensory Neuropathy MetaADEDB
Peritonitis MetaADEDB
Periventricular Leukomalacia MetaADEDB
Pleural Effusion MetaADEDB
Pleurisy MetaADEDB
Premature Baby MetaADEDB
Progesterone Receptor Assay MetaADEDB
Prostatic Disorder MetaADEDB
Protein Total Decreased MetaADEDB
Pustular Psoriasis MetaADEDB
Pyelonephritis MetaADEDB
Radiation Mucositis MetaADEDB
Radicular Pain MetaADEDB
Reflux Esophagitis MetaADEDB
Regurgitation Of Food MetaADEDB
Renal Cyst MetaADEDB
Renin Increased MetaADEDB
Retinal Bleeding MetaADEDB
Retinal Ischaemia MetaADEDB
Retinal Vein Occlusion MetaADEDB
Retracted Nipple MetaADEDB
Rhabdomyolysis MetaADEDB
Sedative Therapy MetaADEDB
Sinus Bradycardia MetaADEDB
Sjogren Syndrome MetaADEDB
Skin Lesion MetaADEDB
Skin Neoplasm Excision MetaADEDB
Small Intestine Carcinoma MetaADEDB
Speech Disorder MetaADEDB
Spinal Compression Fracture MetaADEDB
Squamous Cell Carcinoma Of Skin MetaADEDB
Streptococcal Infection MetaADEDB
Stridor MetaADEDB
Subdural Haemorrhage MetaADEDB
Subileus MetaADEDB
Sudden Onset Of Sleep MetaADEDB
Thyroid Cancer MetaADEDB
Thyroid Neoplasia MetaADEDB
Toxic Skin Eruption MetaADEDB
Transient Ischaemic Attack MetaADEDB
Tumour Marker Increased MetaADEDB
Urine Abnormality MetaADEDB
Urine Sodium Decreased MetaADEDB
Vith Nerve Disorder MetaADEDB
Wrong Drug Administered MetaADEDB
X-Ray Gastrointestinal Tract Abnormal MetaADEDB

InAADR: Drug-Protein-ADRs database