InAADR

Drug Information

Drug Name: bosutinib (380843-75-4)
PubChem ID: 5328940
SMILES: CN1CCN(CC1)CCCOC2=C(C=C3C(=C2)N=CC(=C3NC4=CC(=C(C=C4Cl)Cl)OC)C#N)OC
InchiKey: UBPYILGKFZZVDX-UHFFFAOYSA-N
Therapeutic Category: Antineoplastic Agents

Computed Drug Properties

Molecular Weight (dalton): 530.456
LogP: 5.19038
Ring Count: 3
Hydrogen Bond Acceptor Count: 8
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 82.88

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort PROTECT
Abdominal Pain PROTECT
Abdominal Pain PROTECT
Abdominal Pain PROTECT
Abdominal Tenderness PROTECT
Acne PROTECT
Acute Pulmonary Oedema PROTECT
Alanine Aminotransferase Increased PROTECT
Amylase Increased PROTECT
Anaemia PROTECT
Anaphylactic Shock PROTECT
Arthralgia PROTECT
Aspartate Aminotransferase Increased PROTECT
Asthenia PROTECT
Atypical Pneumonia PROTECT
Back Pain PROTECT
Blood Bilirubin Increased PROTECT
Blood Creatine Phosphokinase Increased PROTECT
Blood Creatinine Increased PROTECT
Bronchitis PROTECT
Bronchopneumonia PROTECT
Chest Discomfort PROTECT
Chest Pain PROTECT
Cough PROTECT
Decreased Appetite PROTECT
Dehydration PROTECT
Diarrhoea PROTECT
Dizziness PROTECT
Drug Eruption PROTECT
Drug Hypersensitivity PROTECT
Dysgeusia PROTECT
Dyspnoea PROTECT
Electrocardiogram Qt Prolonged PROTECT
Erythema Multiforme PROTECT
Exfoliative Rash PROTECT
Face Oedema PROTECT
Fatigue PROTECT
Febrile Neutropenia PROTECT
Gamma-Glutamyltransferase Increased PROTECT
Gastric Haemorrhage PROTECT
Gastritis PROTECT
Gastrointestinal Haemorrhage PROTECT
Gastrointestinal Pain PROTECT
Granulocytopenia PROTECT
Headache PROTECT
Hepatic Function Abnormal PROTECT
Hepatitis PROTECT
Hepatitis Toxic PROTECT
Hepatotoxicity PROTECT
Hyperkalaemia PROTECT
Hypophosphataemia PROTECT
Influenza PROTECT
Leukopenia PROTECT
Lipase Increased PROTECT
Liver Injury PROTECT
Lobar Pneumonia PROTECT
Localised Oedema PROTECT
Long Qt Syndrome PROTECT
Lower Respiratory Tract Infection PROTECT
Malaise PROTECT
Myalgia PROTECT
Nasopharyngitis PROTECT
Nausea PROTECT
Neutropenia PROTECT
Oedema PROTECT
Oedema Peripheral PROTECT
Pain PROTECT
Pancreatitis Acute PROTECT
Pericardial Effusion PROTECT
Pericarditis PROTECT
Pleural Effusion PROTECT
Pneumonia PROTECT
Pruritus PROTECT
Pulmonary Hypertension PROTECT
Pyrexia PROTECT
Rash PROTECT
Rash Generalised PROTECT
Rash Macular PROTECT
Rash Maculo-Papular PROTECT
Rash Papular PROTECT
Rash Pruritic PROTECT
Renal Failure PROTECT
Renal Failure Acute PROTECT
Renal Impairment PROTECT
Respiratory Failure PROTECT
Respiratory Tract Infection PROTECT
Respiratory Tract Infection Viral PROTECT
Thrombocytopenia PROTECT
Tinnitus PROTECT
Upper Gastrointestinal Haemorrhage PROTECT
Upper Respiratory Tract Infection PROTECT
Urticaria PROTECT
Viral Upper Respiratory Tract Infection PROTECT
Vomiting PROTECT

InAADR: Drug-Protein-ADRs database