InAADR

Drug Information

Drug Name: Tocilizumab (375823-41-9)
PubChem ID: 122173035
SMILES: C[C@@]12CC[C@@H]3C([C@H]1CCC2O)C(CC4=C3C=CC(=C4)O)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F
InchiKey: VWUXBMIQPBEWFH-ZQNGPTJTSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 606.782
LogP: 8.6826
Ring Count: 1
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 57.53

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Pain PROTECT
Abdominal Pain ADReCS
Abscess ADReCS
Alanine Aminotransferase Increased ADReCS
Anaphylactic Reaction PROTECT
Angioedema PROTECT
Antibody Test Positive ADReCS
Arthralgia PROTECT
Arthritis Bacterial ADReCS
Aspartate Aminotransferase Increased PROTECT
Aspergillus Infection PROTECT
Bacterial Infection PROTECT
Blood Bilirubin Increased PROTECT
Blood Cholesterol Increased PROTECT
Blood Immunoglobulin G Decreased PROTECT
Bronchitis ADReCS
Candida Infection PROTECT
Cellulitis ADReCS
Coccidioidomycosis PROTECT
Conjunctivitis PROTECT
Cough PROTECT
Diarrhoea PROTECT
Diverticulitis ADReCS
Dizziness ADReCS
Drug Specific Antibody Present PROTECT
Dyspnoea PROTECT
Epigastric Discomfort PROTECT
Fistula ADReCS
Fungal Infection PROTECT
Gastric Ulcer PROTECT
Gastritis ADReCS
Gastroenteritis ADReCS
Gastrointestinal Perforation ADReCS
Headache ADReCS
Hepatic Enzyme Decreased ADReCS
Herpes Zoster ADReCS
Hypercholesterolaemia PROTECT
Hypersensitivity PROTECT
Hypertension ADReCS
Hypertriglyceridaemia PROTECT
Hypotension PROTECT
Hypothyroidism PROTECT
Infusion Related Reaction PROTECT
Interstitial Lung Disease PROTECT
Leukopenia PROTECT
Lung Infection PROTECT
Mouth Ulceration ADReCS
Nasopharyngitis ADReCS
Nausea PROTECT
Neoplasm Malignant ADReCS
Nephrolithiasis PROTECT
Neutralising Antibodies PROTECT
Neutralising Antibodies Positive ADReCS
Neutropenia PROTECT
Neutropenic Infection PROTECT
Neutrophil Count Decreased ADReCS
Oedema Peripheral PROTECT
Opportunistic Infection PROTECT
Oral Herpes PROTECT
Otitis Media PROTECT
Pancytopenia PROTECT
Peritonitis ADReCS
Platelet Count Decreased PROTECT
Pneumocystis Jirovecii Infection PROTECT
Pneumonia ADReCS
Pneumonitis PROTECT
Pruritus ADReCS
Pulmonary Fibrosis PROTECT
Rash ADReCS
Sepsis ADReCS
Skin Reaction ADReCS
Stomatitis PROTECT
Transaminases Increased ADReCS
Tuberculosis PROTECT
Upper Respiratory Tract Infection ADReCS
Urinary Tract Infection ADReCS
Urticaria ADReCS
Varicella PROTECT
Viral Infection PROTECT
Weight Increased PROTECT

InAADR: Drug-Protein-ADRs database