InAADR

Drug Information

Drug Name: Megestrol (3562-63-8)
PubChem ID: 19090
SMILES: CC1=C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@@]3(C(=O)C)O)C)[C@@]4(C1=CC(=O)CC4)C
InchiKey: VXIMPSPISRVBPZ-NWUMPJBXSA-N
Therapeutic Category: Antineoplastic Agents, Contraceptive Agents, Contraceptives, Reproductive Control Agents

Computed Drug Properties

Molecular Weight (dalton): 342.479
LogP: 4.0045
Ring Count: 0
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 54.37

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abasia MetaADEDB
Abdominal Pain ADReCS
Abnormal Lfts MetaADEDB
Abnormal Vision MetaADEDB
Abscess MetaADEDB
Abscess Oral MetaADEDB
Acid Reflux MetaADEDB
Acidosis MetaADEDB
Acne MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Activities Of Daily Living Impaired MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Respiratory Failure MetaADEDB
Adenocarcinoma MetaADEDB
Adenopathy MetaADEDB
Adrenal Insufficiency ADReCS
Adynamic Ileus MetaADEDB
Affect Lability ADReCS
Afib MetaADEDB
Albuminuria ADReCS
Allergic Rhinitis MetaADEDB
Alopecia ADReCS
Alveolar Osteitis MetaADEDB
Amblyopia ADReCS
Anaemia ADReCS
Anemia Aplastic MetaADEDB
Anhedonia MetaADEDB
Anorexia MetaADEDB
Anxiety MetaADEDB
Aortic Arteriosclerosis MetaADEDB
Aortic Calcification MetaADEDB
Aphagia MetaADEDB
Arrhythmia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arterial Rupture MetaADEDB
Arteriosclerosis MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthropathy MetaADEDB
Ascites MetaADEDB
Aspiration Pneumonia MetaADEDB
Asthenia ADReCS
Asthma MetaADEDB
Asystole MetaADEDB
Atelectasis MetaADEDB
Atrial Ectopic Beats MetaADEDB
Atrial Tachycardia MetaADEDB
Atrioventricular Block First Degree MetaADEDB
Atrophy MetaADEDB
Azotaemia MetaADEDB
Back Ache MetaADEDB
Bacteria Urine MetaADEDB
Bacteria Urine Identified MetaADEDB
Bacterial Pneumonia MetaADEDB
Bacterial Toxaemia MetaADEDB
Balance Disorder MetaADEDB
Bile Duct Stone MetaADEDB
Biopsy Bladder Abnormal MetaADEDB
Biopsy Skin MetaADEDB
Birth Defect MetaADEDB
Bk Virus Infection MetaADEDB
Bladder Dilatation MetaADEDB
Bladder Inflammation MetaADEDB
Bleeding Gums MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Bicarbonate Decreased MetaADEDB
Blood Calcium MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Glucose Abnormal MetaADEDB
Blood Glucose Decreased ADReCS
Blood Lactate Dehydrogenase Increased ADReCS
Blood Osmolarity Decreased MetaADEDB
Blood Potassium Decreased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Uric Acid Decreased MetaADEDB
Body Temperature Increased ADReCS
Bone Cancer Metastatic MetaADEDB
Bone Cyst MetaADEDB
Bone Debridement MetaADEDB
Bone Density Decreased MetaADEDB
Bone Disorder MetaADEDB
Bone Erosion MetaADEDB
Bone Lesion MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Neoplasm Malignant MetaADEDB
Bone Scan Abnormal MetaADEDB
Bone Swelling MetaADEDB
Brain Oedema MetaADEDB
Breast Cancer ADReCS
Breast Neoplasms MetaADEDB
Breath Sounds MetaADEDB
Bronchitis MetaADEDB
Bruise MetaADEDB
Bulging MetaADEDB
Bundle Branch Block Left MetaADEDB
Burkitt Lymphoma MetaADEDB
Burn Oesophageal MetaADEDB
Bursitis MetaADEDB
Calculus Urethral MetaADEDB
Calculus Urinary MetaADEDB
Candida Sepsis MetaADEDB
Candidiasis ADReCS
Candidiasis Of Mouth MetaADEDB
Carcinoembryonic Antigen Increased MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure ADReCS
Cardiogenic Shock MetaADEDB
Cardiomyopathy ADReCS
Cardiovascular Diseases MetaADEDB
Carpal Tunnel MetaADEDB
Carpal Tunnel Syndrome ADReCS
Cartilage Development Disorder MetaADEDB
Cataract MetaADEDB
Cataract Operation MetaADEDB
Catatonia MetaADEDB
Catheter Related Complication MetaADEDB
Catheter Related Infection MetaADEDB
Catheter Site Infection MetaADEDB
Catheter Thrombosis MetaADEDB
Cellulitis MetaADEDB
Cerebral Atrophy MetaADEDB
Cerebral Ischaemia MetaADEDB
Cervical Neuritis MetaADEDB
Chest Pain ADReCS
Chest Wall Abscess MetaADEDB
Choking Sensation MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Clostridial Infection MetaADEDB
Clostridium Difficile Colitis MetaADEDB
Clotting MetaADEDB
Cold Extremities MetaADEDB
Colitis Ischaemic MetaADEDB
Coma MetaADEDB
Confabulation MetaADEDB
Confusional State ADReCS
Congenital Mitral Valve Incompetence MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Constipated MetaADEDB
Constipation ADReCS
Convulsion ADReCS
Coronary Artery Occlusion MetaADEDB
Cough ADReCS
Crackles Lung MetaADEDB
Cryptogenic Organising Pneumonia MetaADEDB
Csf Protein MetaADEDB
Cushing Syndrome MetaADEDB
Cushingoid ADReCS
Cutaneous Ulcer MetaADEDB
Deafness ADReCS
Death MetaADEDB
Debridement MetaADEDB
Decreased Activity MetaADEDB
Decreased Interest MetaADEDB
Decubitus Ulcer MetaADEDB
Deep Vein Thrombosis ADReCS
Deglutition Disorder MetaADEDB
Dehydration MetaADEDB
Demyelination MetaADEDB
Dental Care MetaADEDB
Dental Pain MetaADEDB
Dermatitis ADReCS
Dermatitis Bullous ADReCS
Dermatosis MetaADEDB
Device Related Infection MetaADEDB
Diabetes Mellitus ADReCS
Diarrhea MetaADEDB
Diarrhoea ADReCS
Dilatation Atrial MetaADEDB
Diplopia MetaADEDB
Discomfort ADReCS
Disease Progression MetaADEDB
Disorder Lung MetaADEDB
Disorder Peripheral Vascular MetaADEDB
Disturbance In Sexual Arousal ADReCS
Dizziness MetaADEDB
Dizziness Exertional MetaADEDB
Drowsiness MetaADEDB
Dry Mouth ADReCS
Duodenitis MetaADEDB
Dysaesthesia MetaADEDB
Dyspepsia ADReCS
Dyspnoea ADReCS
Economic Problem MetaADEDB
Edema Extremities MetaADEDB
Edentulous MetaADEDB
Ejection Fraction Decreased MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Electrolyte Disorder MetaADEDB
Electromechanical Dissociation MetaADEDB
Embolism ADReCS
Embolism Pulmonary MetaADEDB
Embolism Venous ADReCS
Emesis MetaADEDB
Encephalopathy MetaADEDB
Endocarditis MetaADEDB
Endodontic Procedure MetaADEDB
Endometrial Neoplasms MetaADEDB
Endotracheal Intubation Complication MetaADEDB
Enterococcal Sepsis MetaADEDB
Epistaxis MetaADEDB
Epstein-Barr Virus Associated Lymphoproliferative Disorder MetaADEDB
Erectile Dysfunction ADReCS
Erythema Migrans MetaADEDB
Eschar MetaADEDB
Escherichia Sepsis MetaADEDB
Excessive Granulation Tissue MetaADEDB
External Ear Infection MetaADEDB
Extremity Contracture MetaADEDB
Extremity Pain MetaADEDB
Eye Pain MetaADEDB
Facial Neuralgia MetaADEDB
Faecal Incontinence MetaADEDB
Failure To Thrive MetaADEDB
Fatigue MetaADEDB
Febrile Neutropenia MetaADEDB
Feeling Abnormal ADReCS
Feeling Of Body Temperature Change MetaADEDB
Feminization MetaADEDB
Femoral Neck Fracture MetaADEDB
Flank Pain MetaADEDB
Flatulence ADReCS
Fluid Overload MetaADEDB
Fluid Replacement MetaADEDB
Fluid Retention ADReCS
Folliculitis MetaADEDB
Food Intolerance MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastroenteritis MetaADEDB
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Pain ADReCS
General Physical Health Deterioration MetaADEDB
Gingival Disorder MetaADEDB
Glaucoma MetaADEDB
Glucose Low SIDER
Glucose Tolerance Decreased ADReCS
Glucose Tolerance Impaired ADReCS
Gout MetaADEDB
Granulocyte Count Increased MetaADEDB
Granulocytosis MetaADEDB
Gynaecomastia ADReCS
Haemangioma MetaADEDB
Haemoglobin ADReCS
Haemorrhage ADReCS
Haemorrhagic Diathesis MetaADEDB
Haemorrhoids MetaADEDB
Headache ADReCS
Hearing Impaired ADReCS
Heart Rate Increased MetaADEDB
Heart Valve Incompetence MetaADEDB
Hepatic Failure MetaADEDB
Hepatic Neoplasm Malignant MetaADEDB
Hepatitis Acute MetaADEDB
Hepatomegaly ADReCS
Hernia Hiatal MetaADEDB
Hernia Repair MetaADEDB
Herpes Nos SIDER
Herpes Virus Infection ADReCS
Hiccough MetaADEDB
High Frequency Ablation MetaADEDB
Hip Fracture MetaADEDB
Hordeolum MetaADEDB
Hot Flush ADReCS
Hydronephrosis MetaADEDB
Hyperbaric Oxygen Therapy MetaADEDB
Hypercalcaemia ADReCS
Hypercreatininaemia MetaADEDB
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hyperhomocysteinaemia MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hypoaesthesia ADReCS
Hypoaesthesia Facial MetaADEDB
Hypocoagulable State MetaADEDB
Hypokalaemia MetaADEDB
Hypomagnesaemia MetaADEDB
Hyporeflexia MetaADEDB
Hypotension Orthostatic MetaADEDB
Hypothyroid MetaADEDB
Hypovitaminosis MetaADEDB
Hypovolaemia MetaADEDB
Ill-Defined Disorder ADReCS
Immunosuppression MetaADEDB
Impaired Gastric Emptying MetaADEDB
Impaired Healing MetaADEDB
Impaired Work Ability MetaADEDB
Impingement Syndrome MetaADEDB
Implant Site Reaction MetaADEDB
Incontinence ADReCS
Increased Appetite ADReCS
Increased White Blood Cell Count MetaADEDB
Infection MetaADEDB
Infection Urinary Tract MetaADEDB
Infusion Site Mobility Decreased MetaADEDB
Injection Site Cellulitis MetaADEDB
Injection Site Phlebitis MetaADEDB
Insomnia ADReCS
Intermittent Claudication MetaADEDB
International Normalised Ratio Increased MetaADEDB
Interstitial Nephritis MetaADEDB
Intervertebral Disc Degeneration MetaADEDB
Jaw Disorder MetaADEDB
Jaw Fracture MetaADEDB
Joint Contracture MetaADEDB
Joint Effusion MetaADEDB
Joint Lock MetaADEDB
Joint Range Of Motion Decreased MetaADEDB
Kidney Failure MetaADEDB
Lactic Dehydrogenase Activity Increased SIDER
Left Ventricular Dysfunction MetaADEDB
Lethargy ADReCS
Leucopenia MetaADEDB
Leukaemoid Reaction MetaADEDB
Leukocyturia MetaADEDB
Leukopenia ADReCS
Libido Decreased ADReCS
Limb Injury MetaADEDB
Loose Tooth MetaADEDB
Loss Of Weight MetaADEDB
Lower Gastrointestinal Haemorrhage MetaADEDB
Lumbar Radiculopathy MetaADEDB
Lumbar Spinal Stenosis MetaADEDB
Lung Cancer Metastatic MetaADEDB
Lung Consolidation MetaADEDB
Lung Disorder ADReCS
Lung Edema MetaADEDB
Lung Infiltration MetaADEDB
Lung Neoplasm MetaADEDB
Lung Neoplasm Malignant MetaADEDB
Macula Lutea Degeneration MetaADEDB
Major Depression MetaADEDB
Malaise ADReCS
Malignant Neoplasm Progression MetaADEDB
Malnourished MetaADEDB
Mass Excision MetaADEDB
Mastication Disorder MetaADEDB
Meningioma MetaADEDB
Meniscus Lesion MetaADEDB
Menopausal Symptoms ADReCS
Mental Disability ADReCS
Mental Disorder MetaADEDB
Mental Status Changes MetaADEDB
Metabolic Encephalopathy MetaADEDB
Metastases To Liver MetaADEDB
Metastases To Lung MetaADEDB
Metastatic Neoplasm MetaADEDB
Metrorrhagia ADReCS
Mitral Valve Disease MetaADEDB
Mood Swings ADReCS
Multiple Injuries MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Strain MetaADEDB
Muscle Weakness MetaADEDB
Musculoskeletal Chest Pain MetaADEDB
Musculoskeletal Discomfort MetaADEDB
Myelodysplasia MetaADEDB
Myelopathy MetaADEDB
Nasal Septal Perforation MetaADEDB
Nausea ADReCS
Neoplasms Hormone-Dependent MetaADEDB
Nephrogenic Fibrosing Dermopathy MetaADEDB
Neumonia MetaADEDB
Neuralgia MetaADEDB
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Neutropenic Sepsis MetaADEDB
Neutrophil Count Decreased MetaADEDB
Nodule Skin MetaADEDB
Nuclear Magnetic Resonance Imaging Abnormal MetaADEDB
Obstruction Gastric MetaADEDB
Obstructive Uropathy MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Oliguria MetaADEDB
Optic Neuropathy MetaADEDB
Oral Candidiasis ADReCS
Oral Intake Reduced MetaADEDB
Osteitis Deformans MetaADEDB
Osteoarthritis MetaADEDB
Osteomyelitis MetaADEDB
Osteopenia MetaADEDB
Osteosclerosis MetaADEDB
Pain ADReCS
Pallor MetaADEDB
Palpitations ADReCS
Palsies MetaADEDB
Pancreatitis MetaADEDB
Paraesthesia ADReCS
Paraneoplastic Syndrome MetaADEDB
Parkinson MetaADEDB
Periodontitis MetaADEDB
Peritoneal Dialysis Complication MetaADEDB
Peritonitis Bacterial MetaADEDB
Pharyngitis ADReCS
Physical Disability MetaADEDB
Physiotherapy MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pleural Fibrosis MetaADEDB
Pneumonia ADReCS
Po2 Decreased MetaADEDB
Pollakiuria ADReCS
Polymyalgia Rheumatica MetaADEDB
Poor Personal Hygiene MetaADEDB
Portal Hypertensive Gastropathy MetaADEDB
Posture Abnormal MetaADEDB
Protein Total Decreased MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus ADReCS
Psychoses MetaADEDB
Pulmonary Embolism ADReCS
Pulmonary Mass MetaADEDB
Radiation Oesophagitis MetaADEDB
Radiotherapy MetaADEDB
Rash ADReCS
Rash Pustular ADReCS
Recall Phenomenon MetaADEDB
Reflux Esophagitis MetaADEDB
Renal Cyst MetaADEDB
Respiratory Failure MetaADEDB
Respiratory Rate Increased MetaADEDB
Retinal Vein Occlusion MetaADEDB
Retinoic Acid Syndrome MetaADEDB
Rhagades MetaADEDB
Risus Sardonicus MetaADEDB
Salivary Hypersecretion ADReCS
Salivation SIDER
Sarcoma ADReCS
Scar MetaADEDB
Scleral Hyperaemia MetaADEDB
Scoliosis MetaADEDB
Sepsis Syndrome MetaADEDB
Septic Shock MetaADEDB
Sequestrectomy MetaADEDB
Sinusitis MetaADEDB
Skin Desquamation MetaADEDB
Skin Discolouration MetaADEDB
Skin Disorder ADReCS
Skin Hypertrophy MetaADEDB
Skin Induration MetaADEDB
Skin Lesion MetaADEDB
Small Intestinal Obstruction MetaADEDB
Spinal Column Stenosis MetaADEDB
Spinal Cord Compression MetaADEDB
Spinal Decompression MetaADEDB
Spinal Osteoarthritis MetaADEDB
Spondylitis MetaADEDB
Supraventricular Tachycardia MetaADEDB
Surgery MetaADEDB
Sweating SIDER
Synovial Cyst MetaADEDB
Tachycardia Ventricular MetaADEDB
Tendon Disorder MetaADEDB
Therapeutic Response Decreased MetaADEDB
Thinking Abnormal ADReCS
Thromboembolism ADReCS
Thrombophlebitis ADReCS
Thrombosis ADReCS
Thrombosis In Device MetaADEDB
Tooth Extraction MetaADEDB
Tooth Fracture MetaADEDB
Tooth Impacted MetaADEDB
Tumour Flare SIDER
Unresponsive To Stimuli MetaADEDB
Urethral Stenosis MetaADEDB
Urinary Incontinence ADReCS
Urinary Tract Infection ADReCS
Urine Ketone Body Present MetaADEDB
Urine Sodium MetaADEDB
Urosepsis MetaADEDB
Uterine Haemorrhage ADReCS
Uterine Mass MetaADEDB
Vaccination Complication MetaADEDB
Venous Thrombosis ADReCS
Ventricular Fibrillation MetaADEDB
Ventricular Hypokinesia MetaADEDB
Vesiculobullous Rash SIDER
Vitamin B 12 Deficiency MetaADEDB
Vitreous Detachment MetaADEDB
Vomiting ADReCS
Walking Aid User MetaADEDB
Weight Increased ADReCS
White Blood Cell Count Abnormal MetaADEDB
Wound Dehiscence MetaADEDB
Wrist Fracture MetaADEDB

InAADR: Drug-Protein-ADRs database