| Drug Name: | Bupropion (34841-39-9) |
|---|---|
| PubChem ID: | 444 |
| SMILES: | CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C |
| InchiKey: | SNPPWIUOZRMYNY-UHFFFAOYSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 239.746 |
| LogP | : | 3.2993 |
| Ring Count | : | 1 |
| Hydrogen Bond Acceptor Count | : | 2 |
| Hydrogen Bond Donor Count | : | 1 |
| Total Polar Surface Area | : | 29.1 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Clopidogrel (113665-84-2) | Lightheadedness | Synergistic | The reduction in bupropion hydroxylation is due to inhibition of its cytochrome P450 isoenzyme CYP2B6-mediated metabolism by clopidogrel | Effect of clopidogrel and ticlopidine on cytochrome P450 2B6 activity as measured by bupropionhydroxylation |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category