InAADR

Drug Information

Drug Name: Polythiazide (346-18-9)
PubChem ID: 4870
SMILES: CN1C(NC2=CC(=C(C=C2S1(=O)=O)S(=O)(=O)N)Cl)CSCC(F)(F)F
InchiKey: CYLWJCABXYDINA-UHFFFAOYSA-N
Therapeutic Category: Antihypertensive Agents, Cardiovascular Agents, Diuretics, Membrane Transport Modulators, Natriuretic Agents, Sodium Chloride Symporter Inhibitors

Computed Drug Properties

Molecular Weight (dalton): 439.89
LogP: 1.655
Ring Count: 1
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 109.57

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Pain ADReCS
Agitation ADReCS
Agranulocytosis ADReCS
Alkalosis Hypochloraemic ADReCS
Anaemia ADReCS
Angiitis Necrotising SIDER
Anorexia ADReCS
Anxiety ADReCS
Aplastic Anaemia ADReCS
Apnoea ADReCS
Arrhythmia ADReCS
Arthralgia ADReCS
Asthenia ADReCS
Blood Creatinine Abnormal ADReCS
Blood Urea Abnormal ADReCS
Blood Uric Acid Increased ADReCS
Bronchial Spasm MetaADEDB
Chest Pain ADReCS
Chills ADReCS
Cold Extremities ADReCS
Constipation ADReCS
Cough ADReCS
Cramp Muscle SIDER
Cutaneous Vasculitis ADReCS
Decreased Appetite ADReCS
Depression ADReCS
Depressive Disorder Major MetaADEDB
Dermatitis ADReCS
Diarrhoea ADReCS
Disorders Of Excessive Somnolence MetaADEDB
Dizziness ADReCS
Dry Mouth ADReCS
Dry Skin ADReCS
Dysgeusia ADReCS
Dyspepsia MetaADEDB
Epistaxis ADReCS
Erectile Dysfunction MetaADEDB
Exanthema MetaADEDB
Eye Pruritus ADReCS
Fatigue ADReCS
Gastric Irritation SIDER
Glycosuria ADReCS
Gout MetaADEDB
Gout Acute ADReCS
Haemoconcentration ADReCS
Hallucinations MetaADEDB
Headache ADReCS
Hepatitis ADReCS
Hypercalcaemia ADReCS
Hyperglycaemia ADReCS
Hypersensitivity ADReCS
Hypertension MetaADEDB
Hyperuricaemia ADReCS
Hypochloraemia ADReCS
Hypokalaemia ADReCS
Hypokalemia MetaADEDB
Hypomagnesaemia ADReCS
Hyponatraemia ADReCS
Hypotension ADReCS
Hypovolaemia ADReCS
Impotence ADReCS
Jaundice ADReCS
Jaundice Cholestatic ADReCS
Leukopenia ADReCS
Muscle Spasms ADReCS
Muscular Weakness ADReCS
Nausea ADReCS
Nervousness ADReCS
Neuropathy ADReCS
Nocturia ADReCS
Obesity MetaADEDB
Oedema ADReCS
Oropharyngeal Pain ADReCS
Orthostatic Hypotension ADReCS
Palpitations ADReCS
Pancreatitis ADReCS
Paraesthesia ADReCS
Petechiae ADReCS
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Pruritus ADReCS
Purpura ADReCS
Rash ADReCS
Restlessness ADReCS
Sinus Congestion ADReCS
Skin Necrosis ADReCS
Sleep Initiation And Maintenance Disorders MetaADEDB
Social Avoidant Behaviour ADReCS
Somnolence ADReCS
Stevens-Johnson Syndrome ADReCS
Substance Withdrawal Syndrome MetaADEDB
Swelling ADReCS
Syncope ADReCS
Thrombocytopenia ADReCS
Tinnitus ADReCS
Toxic Epidermal Necrolysis ADReCS
Urticaria ADReCS
Vascular Purpura ADReCS
Vasculitis ADReCS
Vasculitis Necrotising ADReCS
Venous Thrombosis ADReCS
Ventricular Dysfunction Left MetaADEDB
Vertigo ADReCS
Vision Blurred ADReCS
Vomiting ADReCS
Weakness SIDER
Withdrawn SIDER
Xanthopsia ADReCS

InAADR: Drug-Protein-ADRs database