| Drug Name: | Cefamandole (34444-01-4) |
|---|---|
| PubChem ID: | 456255 |
| SMILES: | CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)[C@@H](C4=CC=CC=C4)O)SC2)C(=O)O |
| InchiKey: | OLVCFLKTBJRLHI-AXAPSJFSSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 462.513 |
| LogP | : | -0.2256 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 10 |
| Hydrogen Bond Donor Count | : | 3 |
| Total Polar Surface Area | : | 150.54 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Warfarin (81-81-2) | Bleeding | Additive | cephalosporins with the N-methylthiotetrazole side-chain appear to increase the risk of bleeding, and might therefore interact cefamandole to a lesser extent shown to increase the response to warfarin | Gastrointestinal bleeding due to vitamin K deficiency in patients on parenteral cefamandole |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category