InAADR: Drug-Protein-ADRs database

Drug Name:	Moricizine (31883-05-3)
PubChem ID:	34633
SMILES:	CCOC(=O)NC1=CC2=C(C=C1)SC3=CC=CC=C3N2C(=O)CCN4CCOCC4
InchiKey:	FUBVWMNBEHXPSU-UHFFFAOYSA-N
Therapeutic Category:

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug	Toxicity	Interaction Type	Mechanism	Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity	Interacting Protein	Mechanism	Reference
Proarrhythmia	CYP2D6 (P10635)	Proarrhythmic and other toxic effects [ ADR Type 2 ]	Drugs in special patient groups: clinical importance of genomics in drug effects In: Carruthers GS, Hoffmann BB,Melmon KL, Nierenberg DW
Sudden Cardiac Death	Potassium voltage-gated channel subfamily E member 1 (P15382)	Sudden cardiac death due to long-QT syndrome [ ADR Type 2 ]	Genetic and molecular basis of cardiac arrhythmias: impact on clinical management parts I and II
Sudden Cardiac Death	Potassium voltage-gated channel subfamily H member 2 (Q12809)	Sudden cardiac death due to long-QT syndrome [ ADR Type 2 ]	Genetic and molecular basis of cardiac arrhythmias: impact on clinical management parts I and II
Sudden Cardiac Death	Potassium voltage-gated channel subfamily KQT member 1 (P51787)	Sudden cardiac death due to long-QT syndrome [ ADR Type 2 ]	Genetic and molecular basis of cardiac arrhythmias: impact on clinical management parts I and II
Sudden Cardiac Death	Sodium channel protein type 5 subunit alpha (Q14524)	Sudden cardiac death due to long-QT syndrome [ ADR Type 2 ]	Genetic and molecular basis of cardiac arrhythmias: impact on clinical management parts I and II

This panel provides drug-food interactions and their ADRs along with references

Food	Toxicity	Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite	Toxicity	Place of Metabolism	Mechanism	Reference

This panel provides information on drug category

Toxicity	Source
Abdominal Discomfort	ADReCS
Abdominal Pain	ADReCS
Acute Coronary Syndrome	ADReCS
Agitation	ADReCS
Akathisia	ADReCS
Amnesia	ADReCS
Anorexia	ADReCS
Anxiety	ADReCS
Apnoea	ADReCS
Arrhythmia Supraventricular	ADReCS
Arrhythmias Cardiac	MetaADEDB
Asthenia	ADReCS
Asthma	ADReCS
Ataxia	ADReCS
Atrial Fibrillation	ADReCS
Atrioventricular Block	MetaADEDB
Body Temperature Decreased	ADReCS
Body Temperature Increased	ADReCS
Bradycardia	ADReCS
Cardiac Arrest	ADReCS
Cardiac Death	ADReCS
Cardiac Disorder	ADReCS
Cardiac Failure	ADReCS
Cardiac Failure Congestive	ADReCS
Cardiac Fibrillation	ADReCS
Cardiac Flutter	ADReCS
Cardiac Pain	SIDER
Chest Pain	ADReCS
Chills	ADReCS
Coma	ADReCS
Conduction Disorder	ADReCS
Confusional State	ADReCS
Constipation	ADReCS
Convulsion	ADReCS
Coordination Abnormal	ADReCS
Cough	ADReCS
Death	ADReCS
Decreased Appetite	ADReCS
Dermatitis	ADReCS
Diarrhoea	ADReCS
Diplopia	ADReCS
Disturbance In Sexual Arousal	ADReCS
Dizziness	ADReCS
Drug Fever	ADReCS
Dry Mouth	ADReCS
Dry Skin	ADReCS
Dysgeusia	ADReCS
Dyskinesia	ADReCS
Dyspepsia	ADReCS
Dysphagia	ADReCS
Dyspnoea	ADReCS
Dysuria	ADReCS
Embolism	ADReCS
Emotional Distress	ADReCS
Erectile Dysfunction	ADReCS
Euphoric Mood	ADReCS
Eye Pain	ADReCS
Fatigue	ADReCS
Feeling Abnormal	ADReCS
Flatulence	ADReCS
Gait Disturbance	ADReCS
Gastrointestinal Pain	ADReCS
Gastrointestinal Tract Irritation	ADReCS
Hallucination	ADReCS
Hallucinations	MetaADEDB
Headache	ADReCS
Heart Failure	MetaADEDB
Hepatic Function Abnormal	ADReCS
Hepatitis	ADReCS
Hyperhidrosis	ADReCS
Hypertension	ADReCS
Hyperventilation	ADReCS
Hypoaesthesia	ADReCS
Hypotension	ADReCS
Hypothermia	ADReCS
Ileus	ADReCS
Incontinence	ADReCS
Infarction	ADReCS
Jaundice	ADReCS
Libido Decreased	ADReCS
Lip Swelling	ADReCS
Loss Of Consciousness	ADReCS
Memory Loss	MetaADEDB
Myocardial Infarction	ADReCS
Nausea	ADReCS
Nervousness	ADReCS
Nodal Rhythm	ADReCS
Nystagmus	ADReCS
Oedema	ADReCS
Pain	ADReCS
Palpitations	ADReCS
Paraesthesia	ADReCS
Paranoid Disorders	MetaADEDB
Pharyngitis	ADReCS
Pruritus	ADReCS
Pulmonary Edema	MetaADEDB
Pulmonary Embolism	ADReCS
Rash	ADReCS
Renal Pain	ADReCS
Rigors	MetaADEDB
Seizures	MetaADEDB
Shock	ADReCS
Sinus Arrest	ADReCS
Sinusitis	ADReCS
Sleep Disorder	ADReCS
Somnolence	ADReCS
Speech Disorder	ADReCS
Sweating	MetaADEDB
Swelling	ADReCS
Syncope	ADReCS
Tachycardia Ventricular	MetaADEDB
Taste Bitter	ADReCS
Temperature Intolerance	ADReCS
Tension	ADReCS
Thrombocytopenia	ADReCS
Tinnitus	ADReCS
Tremor	ADReCS
Urinary Incontinence	ADReCS
Urinary Retention	ADReCS
Urticaria	ADReCS
Vasodilation	MetaADEDB
Vasodilation Procedure	ADReCS
Ventricular Fibrillation	MetaADEDB
Vertigo	ADReCS
Vision Blurred	ADReCS
Vomiting	ADReCS

Molecular Weight (dalton)	:	427.526
LogP	:	4.1066
Ring Count	:	2
Hydrogen Bond Acceptor Count	:	6
Hydrogen Bond Donor Count	:	1
Total Polar Surface Area	:	71.11

Drug Information

Computed Drug Properties