InAADR

Drug Information

Drug Name: Guanfacine (29110-47-2)
PubChem ID: 3519
SMILES: C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl
InchiKey: INJOMKTZOLKMBF-UHFFFAOYSA-N
Therapeutic Category: Adrenergic Agents, Adrenergic Agonists, Adrenergic alpha-2 Receptor Agonists, Adrenergic alpha-Agonists, Antihypertensive Agents, Cardiovascular Agents, Neurotransmitter Agents

Computed Drug Properties

Molecular Weight (dalton): 246.097
LogP: 1.3359
Ring Count: 1
Hydrogen Bond Acceptor Count: 1
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 81.47

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abnormal Behaviour MetaADEDB
Abnormal Eeg MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Movements MetaADEDB
Abscess Bacterial MetaADEDB
Activities Of Daily Living Impaired MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Kidney Failure MetaADEDB
Acute Pancreatitis MetaADEDB
Adrenal Mass MetaADEDB
Adverse Drug Effect MetaADEDB
Adverse Event MetaADEDB
Adynamic Ileus MetaADEDB
Affect Lability ADReCS
Ageusia MetaADEDB
Aggression MetaADEDB
Agitated MetaADEDB
Agitation ADReCS
Agonal Rhythm MetaADEDB
Alkalosis Hypochloraemic MetaADEDB
Allergic Dermatitis MetaADEDB
Allergic Rhinitis MetaADEDB
Alopecia ADReCS
Altered State Of Consciousness MetaADEDB
Amnesia ADReCS
Amyotrophy MetaADEDB
Anaemia Of Chronic Disease MetaADEDB
Anger MetaADEDB
Anhedonia MetaADEDB
Anticholinergic Syndrome MetaADEDB
Anticonvulsant Drug Level Below Therapeutic MetaADEDB
Anxiety ADReCS
Aortic Aneurysm MetaADEDB
Aortic Calcification MetaADEDB
Aptyalism MetaADEDB
Arrhythmia ADReCS
Arterial Occlusive Disease MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arthralgia ADReCS
Arthritis Bacterial MetaADEDB
Arthritis Rheumatoid MetaADEDB
Arthropathy MetaADEDB
Asthenia ADReCS
Asthma ADReCS
Asthmatic Crisis MetaADEDB
Atrioventricular Block ADReCS
Attempted Suicide MetaADEDB
Attention Deficit Disorder With Hyperactivity MetaADEDB
Autistic Disorder MetaADEDB
Bacteria Urine MetaADEDB
Bacterial Sepsis MetaADEDB
Bacterial Toxaemia MetaADEDB
Beta Haemolytic Streptococcal Infection MetaADEDB
Bile Duct Stone MetaADEDB
Bipolar Disorder MetaADEDB
Bleb MetaADEDB
Blepharospasm MetaADEDB
Blindness ADReCS
Block Heart SIDER
Blood Albumin Decreased MetaADEDB
Blood Calcium Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Pressure Diastolic MetaADEDB
Blood Pressure Inadequately Controlled MetaADEDB
Blood Pressure Increased ADReCS
Blood Pressure Orthostatic Increased MetaADEDB
Blood Urea Increased MetaADEDB
Blunted Affect MetaADEDB
Body Temperature Increased MetaADEDB
Bone Sarcoma MetaADEDB
Bradycardia ADReCS
Brain Abscess MetaADEDB
Breast Calcifications MetaADEDB
Breast Fibrosis MetaADEDB
Breast Lump MetaADEDB
Breast Lump Removal MetaADEDB
Breast Microcalcification MetaADEDB
Bruise MetaADEDB
Capillary Disorder MetaADEDB
Cardiac Failure ADReCS
Cardiac Failure Congestive ADReCS
Cardiac Fibrillation ADReCS
Cataract Operation MetaADEDB
Cerebrovascular Accident ADReCS
Chapped Lips MetaADEDB
Chest Pain ADReCS
Choking Sensation MetaADEDB
Chronic Sinusitis MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Cognitive Disorder MetaADEDB
Cold Extremities MetaADEDB
Completed Suicide MetaADEDB
Complex Partial Seizures MetaADEDB
Condition Aggravated MetaADEDB
Confabulation MetaADEDB
Confusional State ADReCS
Congenital Tricuspid Valve Incompetence MetaADEDB
Congestive Cardiomyopathy ADReCS
Conjunctivitis ADReCS
Constipated MetaADEDB
Constipation ADReCS
Convulsion ADReCS
Coughing Blood MetaADEDB
Cramp Muscle SIDER
Cramps Of Lower Extremities SIDER
Creatinine Renal Clearance Increased MetaADEDB
Cryptococcosis MetaADEDB
Csf Monocyte Count Decreased MetaADEDB
Deafness MetaADEDB
Decreased Appetite ADReCS
Demyelination MetaADEDB
Depression ADReCS
Dermatitis ADReCS
Dermatitis Exfoliative ADReCS
Developmental Disabilities MetaADEDB
Diabetic Acidosis MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Discomfort ADReCS
Disease Of Liver MetaADEDB
Disorder Of Globe MetaADEDB
Disorder Renal MetaADEDB
Disorders Of Excessive Somnolence MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Diverticulitis MetaADEDB
Diverticulum MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Dizziness Postural ADReCS
Drowsiness SIDER
Drug Screen Positive MetaADEDB
Dry Mouth ADReCS
Dysgeusia ADReCS
Dyspepsia ADReCS
Dysphagia ADReCS
Dysphasia MetaADEDB
Dysphonia MetaADEDB
Dyspnoea ADReCS
Dysthymic Disorder MetaADEDB
Dystonia MetaADEDB
Dysuria MetaADEDB
Ecg Signs Of Ventricular Hypertrophy MetaADEDB
Economic Problem MetaADEDB
Educational Problem MetaADEDB
Electrocardiogram Qt Prolonged MetaADEDB
Electrolyte Disorder MetaADEDB
Emesis MetaADEDB
Emotional Disorder MetaADEDB
Emotional Distress MetaADEDB
Enterovesical Fistula MetaADEDB
Enuresis ADReCS
Erectile Dysfunction ADReCS
Ethmoid Sinus Surgery MetaADEDB
Excess Potassium MetaADEDB
Excessive Thirst MetaADEDB
Extrapyramidal Disorder MetaADEDB
Extraskeletal Ossification MetaADEDB
Extrasystoles Ventricular MetaADEDB
Eye Disorder SIDER
Eye Rolling MetaADEDB
Faeces Discoloured MetaADEDB
Failure To Thrive MetaADEDB
Fatigue ADReCS
Fatty Liver MetaADEDB
Fear Of Death MetaADEDB
Feeling Abnormal ADReCS
Feeling Of Despair MetaADEDB
Fibrous Histiocytoma MetaADEDB
Foaming At Mouth MetaADEDB
Food Craving MetaADEDB
Gastric Disorder ADReCS
Gastrointestinal Pain ADReCS
Gaze Palsy MetaADEDB
Globulinuria MetaADEDB
Glomerular Filtration Rate Decreased MetaADEDB
Goiter MetaADEDB
Haematoma MetaADEDB
Hair Plucking MetaADEDB
Hallucinations MetaADEDB
Head Injury MetaADEDB
Headache ADReCS
Hematoma Subdural MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Function Abnormal ADReCS
Hernia Inguinal MetaADEDB
Herpes Zoster MetaADEDB
Hesitancy MetaADEDB
Hot Flash MetaADEDB
Hyperammonaemia MetaADEDB
Hyperhidrosis ADReCS
Hyperlipaemia MetaADEDB
Hypersensitivity ADReCS
Hypersomnia ADReCS
Hypertension ADReCS
Hypertensive SIDER
Hypertensive Heart Disease MetaADEDB
Hypokinesia ADReCS
Hypotension ADReCS
Hypotension Orthostatic MetaADEDB
Ill-Defined Disorder ADReCS
Immune System Disorder SIDER
Impotence ADReCS
Impulsive Behaviour MetaADEDB
Incontinence ADReCS
Infarction ADReCS
Infection Urinary Tract MetaADEDB
Infusion Related Reaction MetaADEDB
Initial Insomnia SIDER
Injection Site Erythema MetaADEDB
Injection Site Stinging MetaADEDB
Insomnia ADReCS
Intention Tremor MetaADEDB
Intentional Misuse MetaADEDB
Iritis ADReCS
Irritability ADReCS
Judgement Impaired MetaADEDB
Lacrimation Increased MetaADEDB
Leg Cramps ADReCS
Leg Pain ADReCS
Lethargy ADReCS
Leucopenia MetaADEDB
Leukocyturia MetaADEDB
Libido Decreased ADReCS
Liver Function Test Abnormal ADReCS
Logorrhoea MetaADEDB
Loss Of Consciousness ADReCS
Lung Abscess MetaADEDB
Lung Fibrosis MetaADEDB
Lung Neoplasm MetaADEDB
Major Depression MetaADEDB
Malaise ADReCS
Malnourished MetaADEDB
Masked Facies MetaADEDB
Mastectomy MetaADEDB
Mean Platelet Volume Decreased MetaADEDB
Medication Tampering MetaADEDB
Mental Disorder MetaADEDB
Mental Status Changes MetaADEDB
Metamyelocyte Count Increased MetaADEDB
Metastases To Lymph Nodes MetaADEDB
Middle Insomnia ADReCS
Mineral Metabolism Disorder MetaADEDB
Mitral Valve Sclerosis MetaADEDB
Mononucleosis Syndrome MetaADEDB
Monoplegia MetaADEDB
Mouth Pain MetaADEDB
Movement Disorder MetaADEDB
Multiple Drug Overdose MetaADEDB
Multiple Injuries MetaADEDB
Multiple Myeloma MetaADEDB
Muscle Disorder MetaADEDB
Muscle Spasms ADReCS
Muscular Weakness ADReCS
Musculoskeletal Discomfort ADReCS
Musculoskeletal Stiffness MetaADEDB
Myalgia ADReCS
Myocardiac Abscess MetaADEDB
Myocardial Infarction ADReCS
Nausea ADReCS
Nephrolithiasis MetaADEDB
Nephrotic Syndrome MetaADEDB
Nervousness ADReCS
Neurobehavioral Manifestations MetaADEDB
Neurotransmitter Level Altered MetaADEDB
Neutrophil Count Decreased MetaADEDB
Nightmare ADReCS
Nocturia ADReCS
Oculogyration MetaADEDB
Oedema ADReCS
Off Label Use MetaADEDB
Oppositional Defiant Disorder MetaADEDB
Optic Disc Edema MetaADEDB
Orthostatic Hypotension ADReCS
Osteoarthritis MetaADEDB
Osteopenia MetaADEDB
Osteosarcoma Localised MetaADEDB
Overdose MetaADEDB
Pain ADReCS
Pain In Extremity ADReCS
Pallor ADReCS
Palpitation MetaADEDB
Palpitations ADReCS
Pancreatic Abscess MetaADEDB
Paraesthesia ADReCS
Paranasal Sinus Hypersecretion MetaADEDB
Paresis ADReCS
Pharmaceutical Product Complaint MetaADEDB
Pharyngitis Streptococcal MetaADEDB
Pharyngolaryngeal Pain MetaADEDB
Physical Assault MetaADEDB
Pleural Effusion MetaADEDB
Pneumaturia MetaADEDB
Pneumonia Viral MetaADEDB
Pollakiuria ADReCS
Poor Quality Sleep MetaADEDB
Post Herpetic Neuralgia MetaADEDB
Post Traumatic Stress Disorder MetaADEDB
Postmenopausal Bleeding MetaADEDB
Postural Orthostatic Tachycardia Syndrome MetaADEDB
Product Quality Issue MetaADEDB
Pruritus ADReCS
Pulmonary Mass MetaADEDB
Purpura ADReCS
Pyoderma Gangrenosum MetaADEDB
Radiotherapy MetaADEDB
Rash ADReCS
Reaction To Medical Agent Preservatives MetaADEDB
Renal Abscess MetaADEDB
Renal Artery Stenosis MetaADEDB
Renal Cyst MetaADEDB
Renal Failure ADReCS
Renal Failure Acute ADReCS
Renal Impairment MetaADEDB
Respiratory Tract Congestion MetaADEDB
Retinitis MetaADEDB
Retrocollis MetaADEDB
Retrosternal Pain SIDER
Rhinitis ADReCS
Screaming MetaADEDB
Sedation ADReCS
Self Injurious Behaviour MetaADEDB
Self Mutilation MetaADEDB
Self-Injurious Ideation MetaADEDB
Serum Ferritin Increased MetaADEDB
Shock ADReCS
Sinus Antrostomy MetaADEDB
Sinus Arrhythmia ADReCS
Sinus Bradycardia MetaADEDB
Sinusitis MetaADEDB
Skin Discolouration MetaADEDB
Skin Exfoliation ADReCS
Skin Laceration MetaADEDB
Social Avoidant Behaviour MetaADEDB
Somnolence ADReCS
Spinal Osteoarthritis MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Staphylococcal Infection MetaADEDB
Staring MetaADEDB
Stenotrophomonas Infection MetaADEDB
Subarachnoid Haemorrhage MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Sweating SIDER
Syncope ADReCS
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Tachyphylaxis MetaADEDB
Tearfulness MetaADEDB
Tension ADReCS
Testicular Disorder ADReCS
Thought Insertion MetaADEDB
Tic Disorders MetaADEDB
Tinnitus ADReCS
Tremor ADReCS
Tunnel Vision MetaADEDB
Unevaluable Event MetaADEDB
Upset Stomach SIDER
Urinary Incontinence ADReCS
Vascular Purpura ADReCS
Ventricular Dysfunction Left MetaADEDB
Ventricular Premature Complexes MetaADEDB
Vertigo ADReCS
Vision Abnormal ADReCS
Vision Blurred ADReCS
Visual Acuity Reduced ADReCS
Visual Impairment ADReCS
Vomiting ADReCS
Weakness SIDER
Weight Gain MetaADEDB
Weight Increased ADReCS
Wheeze MetaADEDB
Xerostomia MetaADEDB

InAADR: Drug-Protein-ADRs database