| Drug Name: | Alprazolam (28981-97-7) |
|---|---|
| PubChem ID: | 2118 |
| SMILES: | CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4 |
| InchiKey: | VREFGVBLTWBCJP-UHFFFAOYSA-N |
| Therapeutic Category: | Anti-Anxiety Agents, Central Nervous System Agents, Central Nervous System Depressants, GABA Agents, GABA Modulators, Hypnotics and Sedatives, Neurotransmitter Agents, Psychotropic Drugs, Tranquilizing Agents |
| Molecular Weight (dalton) | : | 308.772 |
| LogP | : | 3.58012 |
| Ring Count | : | 3 |
| Hydrogen Bond Acceptor Count | : | 4 |
| Hydrogen Bond Donor Count | : | 0 |
| Total Polar Surface Area | : | 43.07 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
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This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Amnesia | Platelet-activating factor receptor (P25105) | Retrograde amnesia of alprazolam may be mediated through the blockade of PAF receptors. [ ADR Type 1 ] | Possible mechanism of alprazolam-induced amnesia in mice |
| Anterograde Amnesia | benzodiazepine omega 2 receptor subtype (P30536) | Anterograde amnesia produced by alprazolam may be mediated through the activation of benzodiazepine receptors. [ ADR Type 1 ] | Possible mechanism of alprazolam-induced amnesia in mice |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category