InAADR

Drug Information

Drug Name: Nicergoline (27848-84-6)
PubChem ID: 34040
SMILES: CN1C[C@@H](C[C@]2([C@H]1CC3=CN(C4=CC=CC2=C34)C)OC)COC(=O)C5=CC(=CN=C5)Br
InchiKey: YSEXMKHXIOCEJA-FVFQAYNVSA-N
Therapeutic Category: Adrenergic Agents, Adrenergic alpha-Antagonists, Adrenergic Antagonists, Cardiovascular Agents, Central Nervous System Agents, Neurotransmitter Agents, Nootropic Agents, Vasodilator Agents

Computed Drug Properties

Molecular Weight (dalton): 484.394
LogP: 3.9109
Ring Count: 3
Hydrogen Bond Acceptor Count: 6
Hydrogen Bond Donor Count: 0
Total Polar Surface Area: 56.59

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Distension MetaADEDB
Abdominal Pain MetaADEDB
Abnormal Faeces MetaADEDB
Abnormal Movements MetaADEDB
Abulia MetaADEDB
Acne Rosacea MetaADEDB
Acute Brain Syndrome MetaADEDB
Acute Coronary Syndrome MetaADEDB
Acute Hepatic Failure MetaADEDB
Acute Leukaemia MetaADEDB
Acute Myocardial Infarction MetaADEDB
Adh Inappropriate MetaADEDB
Adverse Event MetaADEDB
Aggression MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Allergic Dermatitis MetaADEDB
Allergic Granulomatous Angiitis MetaADEDB
Altered Bowel Function MetaADEDB
Altered State Of Consciousness MetaADEDB
Alveolitis MetaADEDB
Amnesia MetaADEDB
Anaemia MetaADEDB
Ankle Fracture MetaADEDB
Anorexia MetaADEDB
Aortic Calcification MetaADEDB
Aortic Dissection MetaADEDB
Aptyalism MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteritis MetaADEDB
Arthralgia MetaADEDB
Asbestosis MetaADEDB
Aspartate Aminotransferase Increase MetaADEDB
Aspiration Pneumonia MetaADEDB
Autonomic Instability MetaADEDB
Back Ache MetaADEDB
Balance Disorder MetaADEDB
Belching MetaADEDB
Beta-N-Acetyl-D-Glucosaminidase Increased MetaADEDB
Biliary Fibrosis MetaADEDB
Biliary Tract Disorder MetaADEDB
Black Stools MetaADEDB
Bladder Retention MetaADEDB
Blood Creatine Increased MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Glucose Abnormal MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Osmolarity Decreased MetaADEDB
Blood Phosphorus Increased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Diastolic Decreased MetaADEDB
Blood Pressure Systolic Decreased MetaADEDB
Blood Sodium MetaADEDB
Blood Sodium Abnormal MetaADEDB
Blood Urea Abnormal MetaADEDB
Blood Urea Increased MetaADEDB
Body Temperature Increased MetaADEDB
Bone Inflammation MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Pain MetaADEDB
Bowel Sounds Abnormal MetaADEDB
Bradycardia MetaADEDB
Brain Oedema MetaADEDB
C-Reactive Protein Increased MetaADEDB
Calcification Metastatic MetaADEDB
Carcinoma Of The Cervix MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Failure Acute MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cataract MetaADEDB
Cataract Operation MetaADEDB
Cerebellar Ataxia MetaADEDB
Cerebellar Haemorrhage MetaADEDB
Cerebral Circulatory Failure MetaADEDB
Cerebral Haemorrhage MetaADEDB
Cerebral Infarct MetaADEDB
Cerebral Vascular Disorder MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Chest Pain MetaADEDB
Chest X-Ray Abnormal MetaADEDB
Chronic Kidney Disease MetaADEDB
Cognitive Deterioration MetaADEDB
Condition Aggravated MetaADEDB
Confabulation MetaADEDB
Conjunctival Hyperaemia MetaADEDB
Cryptogenic Organising Pneumonia MetaADEDB
Cytolytic Hepatitis MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitis Bullous MetaADEDB
Dermatitis Medicamentosa MetaADEDB
Difficulty In Walking MetaADEDB
Disease Of Liver MetaADEDB
Disease Recurrence MetaADEDB
Disorder Renal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Diverticulosis MetaADEDB
Drowsiness MetaADEDB
Dyschezia MetaADEDB
Eating Disorder MetaADEDB
Ebv Infection MetaADEDB
Eczema MetaADEDB
Electrocardiogram St Segment Elevation MetaADEDB
Elevated Erythrocyte Sedimentation Rate MetaADEDB
Encephalopathy MetaADEDB
Enterocolitis MetaADEDB
Eosinophilia MetaADEDB
Epilepsy MetaADEDB
Epstein-Barr Virus Test Positive MetaADEDB
Eruption MetaADEDB
Erythema MetaADEDB
Excess Potassium MetaADEDB
Excessive Sleepiness MetaADEDB
Extrapyramidal Disorder MetaADEDB
Facial Palsy MetaADEDB
Fever MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastrointestinal Stromal Tumour MetaADEDB
Glomerular Vascular Disorder MetaADEDB
Haemodialysis MetaADEDB
Haemorrhage Subcutaneous MetaADEDB
Haemorrhagic Diathesis MetaADEDB
Headache MetaADEDB
Hematoma Subdural MetaADEDB
Hemianopia Homonymous MetaADEDB
Hemiparesis MetaADEDB
Hemiplegia MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Function Abnormal MetaADEDB
Hepatitis Fulminant MetaADEDB
Hernia Hiatal MetaADEDB
Histiocytosis Haematophagic MetaADEDB
Hodgkin Disease MetaADEDB
Hyperparathyroidism MetaADEDB
Hyperphosphataemia MetaADEDB
Hypertension MetaADEDB
Hypoglycaemia Neonatal MetaADEDB
Hypokinesia MetaADEDB
Hypophagia MetaADEDB
Hypoproteinaemia MetaADEDB
Hypotension MetaADEDB
Ild MetaADEDB
Incontinence MetaADEDB
Increased Platelet Count MetaADEDB
Increased White Blood Cell Count MetaADEDB
Intraoperative Complications MetaADEDB
Iridocyclitis MetaADEDB
Ischaemic Hepatitis MetaADEDB
Itch MetaADEDB
Large Intestine Perforation MetaADEDB
Leucopenia MetaADEDB
Leukopenia Neonatal MetaADEDB
Mental Impairment MetaADEDB
Movement Disorder MetaADEDB
Myoglobin Blood Increased MetaADEDB
Myoglobin Urine Present MetaADEDB
Necrotising Fasciitis MetaADEDB
Nephritis Interstitial MetaADEDB
Neutrophil Count Abnormal MetaADEDB
Oesophagitis Haemorrhagic MetaADEDB
Oral Intake Reduced MetaADEDB
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Pancreatic Cancer MetaADEDB
Parkinsonian Disorders MetaADEDB
Peripheral Nervous System Diseases MetaADEDB
Petechia MetaADEDB
Platelet Count MetaADEDB
Polyneuropathy MetaADEDB
Polyuria MetaADEDB
Poriomania MetaADEDB
Prinzmetal Angina MetaADEDB
Prinzmetal Variant Angina MetaADEDB
Pulmonary Hypertension MetaADEDB
Pulmonary Infarction MetaADEDB
Pulmonary Mass MetaADEDB
Pulse Abnormal MetaADEDB
Rales MetaADEDB
Rectal Ulcer Haemorrhage MetaADEDB
Red Blood Cell Count Increased MetaADEDB
Renal Impairment MetaADEDB
Renal Insufficiency MetaADEDB
Respiratory Failure MetaADEDB
Retinal Vein Occlusion MetaADEDB
Rhabdomyolysis MetaADEDB
Rib Fracture MetaADEDB
Sick Sinus Syndrome MetaADEDB
Skin Tightness MetaADEDB
Sputum Discoloured MetaADEDB
Sudden Death MetaADEDB
Tachycardia MetaADEDB
Therapy Non-Responder MetaADEDB
Thrombotic Stroke MetaADEDB
Tongue Biting MetaADEDB
Tooth Fracture MetaADEDB
Toxic Skin Eruption MetaADEDB
Transient Ischaemic Attack MetaADEDB
Unevaluable Event MetaADEDB
Upper Gastrointestinal Bleeding MetaADEDB
Urethral Haemorrhage MetaADEDB
Urine Output Increased MetaADEDB
Vascular Calcification MetaADEDB
Vomiting Psychogenic MetaADEDB

InAADR: Drug-Protein-ADRs database