InAADR

Drug Information

Drug Name: Flupenthixol (2709-56-0)
PubChem ID: 5281881
SMILES: C1CN(CCN1CC/C=C2/C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F)CCO
InchiKey: NJMYODHXAKYRHW-DVZOWYKESA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 434.527
LogP: 4.6017
Ring Count: 2
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 26.71

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference
Akathisia D(2) dopamine receptor (P14416) Antipsychotic response (D2@ D3@ D4)@antipsychotic-induced tardive dyskinesia (D3)@antipsychotic-induced acute akathisia (D3) [ ADR Type 2 ] Pharmacogenetics and antipsychotic drugs
Akathisia D(3) dopamine receptor (P35462) Antipsychotic response (D2@ D3@ D4)@antipsychotic-induced tardive dyskinesia (D3)@antipsychotic-induced acute akathisia (D3). [ ADR Type 2 ] Pharmacogenetics and antipsychotic drugs
Akathisia D(4) dopamine receptor (P21917) Antipsychotic response (D2@ D3@ D4)@antipsychotic-induced tardive dyskinesia (D3)@antipsychotic-induced acute akathisia (D3) [ ADR Type 2 ] Pharmacogenetics and antipsychotic drugs
Tardive Dyskinesia D(2) dopamine receptor (P14416) Antipsychotic response (D2@ D3@ D4)@antipsychotic-induced tardive dyskinesia (D3)@antipsychotic-induced acute akathisia (D3) [ ADR Type 2 ] Pharmacogenetics and antipsychotic drugs
Tardive Dyskinesia D(3) dopamine receptor (P35462) Antipsychotic response (D2@ D3@ D4)@antipsychotic-induced tardive dyskinesia (D3)@antipsychotic-induced acute akathisia (D3). [ ADR Type 2 ] Pharmacogenetics and antipsychotic drugs
Tardive Dyskinesia D(4) dopamine receptor (P21917) Antipsychotic response (D2@ D3@ D4)@antipsychotic-induced tardive dyskinesia (D3)@antipsychotic-induced acute akathisia (D3) [ ADR Type 2 ] Pharmacogenetics and antipsychotic drugs

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Compartment Syndrome MetaADEDB
Abnormal Behaviour MetaADEDB
Abnormal Dreams MetaADEDB
Abnormal Lfts MetaADEDB
Abnormal Sleep-Related Event MetaADEDB
Abnormal Vision MetaADEDB
Accidental Overdose MetaADEDB
Aching Joints MetaADEDB
Acidosis MetaADEDB
Acute Left Ventricular Failure MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Affect Lability MetaADEDB
Affective Disorder MetaADEDB
Aggression MetaADEDB
Agitated MetaADEDB
Alanine Aminotransferase MetaADEDB
Alanine Aminotransferase Increased MetaADEDB
Alcohol Poisoning MetaADEDB
Allergic Alveolitis MetaADEDB
Ammonia Increased MetaADEDB
Amnesia MetaADEDB
Amyotrophy MetaADEDB
Anaesthesia MetaADEDB
Anger MetaADEDB
Angiitis MetaADEDB
Angle Closure Glaucoma MetaADEDB
Antisocial Behaviour MetaADEDB
Anxiety MetaADEDB
Apathy MetaADEDB
Apparent Death MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arthritis Rheumatoid MetaADEDB
Asphyxia MetaADEDB
Asystole MetaADEDB
Ataxia MetaADEDB
Atrial Tachycardia MetaADEDB
Attempted Suicide MetaADEDB
Aura MetaADEDB
Basal Ganglia Diseases MetaADEDB
Belching MetaADEDB
Bipolar Disorder MetaADEDB
Bladder Retention MetaADEDB
Bleeding Time Prolonged MetaADEDB
Blepharoptosis MetaADEDB
Blepharospasm MetaADEDB
Blood Calcium MetaADEDB
Blood Creatine Phosphokinase Increased MetaADEDB
Blood Creatine Phosphokinase Mb Increased MetaADEDB
Blood Pressure Fluctuation MetaADEDB
Blood Sodium MetaADEDB
Blood Uric Acid MetaADEDB
Body Temperature Increased MetaADEDB
Bradypnoea MetaADEDB
Brain Diseases MetaADEDB
Bruxism MetaADEDB
C-Reactive Protein Increased MetaADEDB
Carbon Monoxide Poisoning MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Enzymes Increased MetaADEDB
Cardiac Failure MetaADEDB
Cardiogenic Shock MetaADEDB
Cardiomyopathy MetaADEDB
Chemotherapeutic Drug Level Increased MetaADEDB
Cholinergic Syndrome MetaADEDB
Chorea MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Cocaine-Related Disorders MetaADEDB
Cogwheel Rigidity MetaADEDB
Cold Extremities MetaADEDB
Colon Injury MetaADEDB
Coma MetaADEDB
Completed Suicide MetaADEDB
Confabulation MetaADEDB
Congenital Mitral Valve Incompetence MetaADEDB
Continuous Haemodiafiltration MetaADEDB
Coprolalia MetaADEDB
Crackles Lung MetaADEDB
Crying MetaADEDB
Cyanosis MetaADEDB
Decreased Libido MetaADEDB
Deglutition Disorder MetaADEDB
Delusion MetaADEDB
Dependence MetaADEDB
Depressed Mood MetaADEDB
Depressive Disorder MetaADEDB
Depressive Symptom MetaADEDB
Diabetic Nephropathy MetaADEDB
Diarrhea MetaADEDB
Diet Refusal MetaADEDB
Disease Progression MetaADEDB
Disseminated Tuberculosis MetaADEDB
Disturbance In Attention MetaADEDB
Drug Interaction MetaADEDB
Drug Level MetaADEDB
Drug Withdrawal MetaADEDB
Dry Skin MetaADEDB
Dyskinesia Drug-Induced MetaADEDB
Dysmorphism MetaADEDB
Dysphasia MetaADEDB
Dysthymic Disorder MetaADEDB
Dystonia MetaADEDB
Echolalia MetaADEDB
Effusion MetaADEDB
Ejaculation Failure MetaADEDB
Electrocardiogram Poor R-Wave Progression MetaADEDB
Elevated Erythrocyte Sedimentation Rate MetaADEDB
Endotracheal Intubation MetaADEDB
Enterocolitis MetaADEDB
Eosinophil Count Increased MetaADEDB
Eosinophilic Myocarditis MetaADEDB
Erectile Dysfunction MetaADEDB
Eruption MetaADEDB
Erysipelas MetaADEDB
Excess Potassium MetaADEDB
Excessive Salivation MetaADEDB
Excessive Sleepiness MetaADEDB
Excessive Thirst MetaADEDB
Eye Rolling MetaADEDB
Fatigue MetaADEDB
Fatty Liver MetaADEDB
Fear Of Eating MetaADEDB
Folliculitis MetaADEDB
Formication MetaADEDB
Frustration MetaADEDB
Gamma-Glutamyltransferase Increased MetaADEDB
Gastrointestinal Disorder MetaADEDB
Gastrointestinal Injury MetaADEDB
Genital Rash MetaADEDB
Graft Infection MetaADEDB
Granuloma MetaADEDB
Haemodynamic Instability MetaADEDB
Haemorrhage Rectum MetaADEDB
Head Injury MetaADEDB
Hepatic Necrosis MetaADEDB
Hepatitis Acute MetaADEDB
Hepatitis Fulminant MetaADEDB
Heroin Dependence MetaADEDB
Herpes Simplex MetaADEDB
Herpes Zoster MetaADEDB
Hiccough MetaADEDB
Hyperhidrosis MetaADEDB
Hyperkinesis MetaADEDB
Hyperlipaemia MetaADEDB
Hyperlipidemias MetaADEDB
Hypoaesthesia MetaADEDB
Hypokinesia MetaADEDB
Hypomagnesaemia MetaADEDB
Hypoparathyroidism MetaADEDB
Hyporeflexia MetaADEDB
Hypotension Orthostatic MetaADEDB
Ill-Defined Disorder MetaADEDB
Impaired Self-Care MetaADEDB
Impulse Control Disorders MetaADEDB
Incontinence MetaADEDB
Increased Platelet Count MetaADEDB
Increased White Blood Cell Count MetaADEDB
Influenza Like Illness MetaADEDB
Intention Tremor MetaADEDB
Intentional Misuse MetaADEDB
Intentional Self-Injury MetaADEDB
International Normalised Ratio Increased MetaADEDB
Joint Effusion MetaADEDB
Knee Arthroplasty MetaADEDB
Laceration MetaADEDB
Learning Disorders MetaADEDB
Lethargy MetaADEDB
Leucopenia MetaADEDB
Leukoencephalopathy MetaADEDB
Leukopenia Neonatal MetaADEDB
Logorrhoea MetaADEDB
Lymphocytes Decreased MetaADEDB
Lymphocytosis MetaADEDB
Mendelson Syndrome MetaADEDB
Mental Disorders MetaADEDB
Mental Impairment MetaADEDB
Metabolic Encephalopathy MetaADEDB
Metastases To Lung MetaADEDB
Mitochondrial Myopathy MetaADEDB
Mononeuropathy MetaADEDB
Mood Altered MetaADEDB
Morbid Thoughts MetaADEDB
Movement Disorders MetaADEDB
Multiple Drug Overdose MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Muscle Disorder MetaADEDB
Muscle Hypertrophy MetaADEDB
Muscle Inflammation MetaADEDB
Nausea MetaADEDB
Nephrolithiasis MetaADEDB
Neuroleptic Malignant Syndrome MetaADEDB
Nightmare MetaADEDB
Nocturia MetaADEDB
Overdose MetaADEDB
Panic Attack MetaADEDB
Paranoid Disorders MetaADEDB
Paranoid Personality Disorder MetaADEDB
Parkinson Disease Secondary MetaADEDB
Pericardial Effusion MetaADEDB
Persecutory Delusion MetaADEDB
Petechia MetaADEDB
Pharyngeal Disorder MetaADEDB
Poor Quality Sleep MetaADEDB
Pressure Of Speech MetaADEDB
Productive Cough MetaADEDB
Psoriasis MetaADEDB
Psychoses Substance-Induced MetaADEDB
Psychotic Disorders MetaADEDB
Respiratory Insufficiency MetaADEDB
Salivary Gland Calculus MetaADEDB
Schizophrenia MetaADEDB
Schizophrenia Paranoid Type MetaADEDB
Scleral Haemorrhage MetaADEDB
Seizures MetaADEDB
Self Mutilation MetaADEDB
Self-Injurious Ideation MetaADEDB
Sensory Disturbance MetaADEDB
Sleep Disorder MetaADEDB
Somatic Hallucination MetaADEDB
Spinning Sensation MetaADEDB
Staring MetaADEDB
Subdural Haemorrhage MetaADEDB
Sudden Death MetaADEDB
Suprapubic Pain MetaADEDB
Syncope Vasovagal MetaADEDB
Synovial Rupture MetaADEDB
Tearfulness MetaADEDB
Temperature Regulation Disorder MetaADEDB
Tetany MetaADEDB
Theft MetaADEDB
Thought Blocking MetaADEDB
Tongue Biting MetaADEDB
Toxic Encephalopathy MetaADEDB
Transaminases Increased MetaADEDB
Troponin Increased MetaADEDB
Urethral Stenosis MetaADEDB
Vein Disorder MetaADEDB
Violence-Related Symptom MetaADEDB
Weight Gain MetaADEDB
Withdrawal Syndrome MetaADEDB
Wound Haemorrhage MetaADEDB

InAADR: Drug-Protein-ADRs database