| Drug Name: | Cefazolin (25953-19-9) |
|---|---|
| PubChem ID: | 33255 |
| SMILES: | CC1=NN=C(S1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)CN4C=NN=N4)SC2)C(=O)O |
| InchiKey: | MLYYVTUWGNIJIB-BXKDBHETSA-N |
| Therapeutic Category: | Anti-Bacterial Agents, Anti-Infective Agents |
| Molecular Weight (dalton) | : | 454.519 |
| LogP | : | -0.63608 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 12 |
| Hydrogen Bond Donor Count | : | 2 |
| Total Polar Surface Area | : | 156.09 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|---|---|---|---|
| Warfarin (81-81-2) | Bleeding | Additive | cephalosporins with the N-methylthiotetrazole side-chain appear to increase the risk of bleeding, and might therefore interact cefazolin to a lesser extent shown to increase the response to warfarin | The comparative influence of prophylactic antibiotics on the prothrombin response to warfarin in the postoperative prosthetic cardiac valve patient Cefamandole, cefazolin, vancomycin |
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
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This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
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This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
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This panel provides information on drug category