| Drug Name: | doxorubicin hydrochloride nephrosis (AN) (25316-40-9) |
|---|---|
| PubChem ID: | 69761881 |
| SMILES: | C[C@H]1[C@H]([C@H](CC(O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl |
| InchiKey: | MWWSFMDVAYGXBV-RDXHWVRHSA-N |
| Therapeutic Category: |
| Molecular Weight (dalton) | : | 579.986 |
| LogP | : | 0.4231 |
| Ring Count | : | 2 |
| Hydrogen Bond Acceptor Count | : | 12 |
| Hydrogen Bond Donor Count | : | 6 |
| Total Polar Surface Area | : | 206.07 |
This panel provides information on interacting drugs and their ADRs along with references
| Interacting drug | Toxicity | Interaction Type | Mechanism | Reference |
|---|
This panel provides drug-protein interaction and their ADRs along with references
| Toxicity | Interacting Protein | Mechanism | Reference |
|---|---|---|---|
| Renal Tubular Injury | Beta-hexosaminidase (P06865) | The urinary excretion of lysozyme and N-acetyl-glucosaminidase@ markers of renal tubular injury@ were significantly increased after 7 or 14 days in rats with doxorubicin hydrochloride nephrosis (AN) [ ADR Type 2 ] | Amelioration of glomerular injury in doxorubicin hydrochloride nephrosis by dimethylthiourea |
| Renal Tubular Injury | Lysozyme (P61626) | The urinary excretion of lysozyme and N-acetyl-glucosaminidase@ markers of renal tubular injury@ were significantly increased after 7 or 14 days in rats with doxorubicin hydrochloride nephrosis (AN) [ ADR Type 2 ] | Amelioration of glomerular injury in doxorubicin hydrochloride nephrosis by dimethylthiourea |
This panel provides drug-food interactions and their ADRs along with references
| Food | Toxicity | Reference |
|---|
This panel provides information on metabolites and their ADRs along with references
| Metabolite | Toxicity | Place of Metabolism | Mechanism | Reference |
|---|
This panel provides information on drug category
| Toxicity | Source |
|---|