InAADR

Drug Information

Drug Name: Difluprednate (23674-86-4)
PubChem ID: 22794987
SMILES: CCCC(=O)O[C@@]1(CC[C@@H]2[C@@]1(CC([C@]3([C@H]2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)C(=O)COC(=O)C
InchiKey: WYQPLTPSGFELIB-LXISTHLCSA-N
Therapeutic Category: Adrenal Cortex Hormones, Glucocorticoids, Hormones

Computed Drug Properties

Molecular Weight (dalton): 508.558
LogP: 3.5195
Ring Count: 0
Hydrogen Bond Acceptor Count: 7
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 106.97

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Compartment Syndrome MetaADEDB
Acne MetaADEDB
Acquired Haemophilia MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Acute Lymphocytic Leukaemia Recurrent MetaADEDB
Adenoviral Haemorrhagic Cystitis MetaADEDB
Adh Inappropriate MetaADEDB
Allergic Dermatitis MetaADEDB
Alveolitis MetaADEDB
Anaemia MetaADEDB
Anal Fistula MetaADEDB
Anterior Chamber Cell ADReCS
Anterior Chamber Flare ADReCS
Aorto-Oesophageal Fistula MetaADEDB
Apathy MetaADEDB
Application Site Discomfort ADReCS
Application Site Irritation ADReCS
Arteritis MetaADEDB
Atrophy Of Skin MetaADEDB
Bacterial Pneumonia MetaADEDB
Band Neutrophil Percentage Increased MetaADEDB
Bence Jones Protein Urine MetaADEDB
Binocular Eye Movement Disorder MetaADEDB
Black Stools MetaADEDB
Blast Cells Present MetaADEDB
Blast Crisis In Myelogenous Leukaemia MetaADEDB
Bleb MetaADEDB
Blepharitis ADReCS
Blindness Unilateral MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Beta-D-Glucan Increased MetaADEDB
Blood Copper Decreased MetaADEDB
Blood Creatine Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Immunoglobulin G Decreased MetaADEDB
Blood Immunoglobulin M Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Pressure Diastolic Decreased MetaADEDB
Blood Uric Acid MetaADEDB
Body Temperature Increased MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Marrow Transplant MetaADEDB
Bradycardia MetaADEDB
Brain Oedema MetaADEDB
Burning Sensation Mucosal MetaADEDB
C-Reactive Protein Increased MetaADEDB
Cachectic MetaADEDB
Candidiasis Of Mouth MetaADEDB
Capillary Disorder MetaADEDB
Cardiac Valve Vegetation MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiogenic Shock MetaADEDB
Cataract ADReCS
Cataract Subcapsular ADReCS
Catheter Placement MetaADEDB
Cellulitis MetaADEDB
Cerebral Infarct MetaADEDB
Cerebral Ventricle Dilatation MetaADEDB
Chronic Graft Versus Host Disease MetaADEDB
Ciliary Hyperaemia ADReCS
Cmv Infection MetaADEDB
Coagulation Time Prolonged MetaADEDB
Colon Cancer Metastatic MetaADEDB
Completed Suicide MetaADEDB
Conjunctival Hyperaemia ADReCS
Conjunctival Oedema ADReCS
Corneal Oedema ADReCS
Corneal Pigmentation ADReCS
Corneal Striae ADReCS
Csf Cell Count MetaADEDB
Csf Monocyte Count Increased MetaADEDB
Csf Pressure Increased MetaADEDB
Cutaneous Ulcer MetaADEDB
Cytomegalovirus Hepatitis MetaADEDB
Cytomegalovirus Test Positive MetaADEDB
Cytomegalovirus Viraemia MetaADEDB
Depigmentation MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatosis MetaADEDB
Dilatation Ventricular MetaADEDB
Discomfort ADReCS
Dizziness Exertional MetaADEDB
Dry Eye ADReCS
Dysstasia MetaADEDB
Ear Disorder MetaADEDB
Ebv Infection MetaADEDB
Endocarditis MetaADEDB
Enlarged Liver MetaADEDB
Episcleritis ADReCS
Erythema MetaADEDB
Erythema Multiforme MetaADEDB
Eye Infection ADReCS
Eye Inflammation ADReCS
Eye Irritation ADReCS
Eye Pain ADReCS
Eye Penetration ADReCS
Eye Pruritus ADReCS
Eye Swelling MetaADEDB
Eyelid Irritation ADReCS
Eyelid Margin Crusting ADReCS
Facial Wasting MetaADEDB
False Positive Laboratory Result MetaADEDB
Foreign Body Sensation In Eyes ADReCS
Gastrointestinal Disorder MetaADEDB
Gastrointestinal Perforation MetaADEDB
Granulocytosis MetaADEDB
Haematoma MetaADEDB
Hair Disease MetaADEDB
Headache ADReCS
Hepatic Enzyme MetaADEDB
Hepatic Function Abnormal MetaADEDB
Herpes Simplex ADReCS
Herpes Virus Infection ADReCS
Hydrocephalus MetaADEDB
Hyperaemia ADReCS
Hypoproteinaemia MetaADEDB
Ild MetaADEDB
Immunoglobulins Decreased MetaADEDB
Infection ADReCS
Infusion Related Reaction MetaADEDB
Intraocular Pressure Increased ADReCS
Iridocyclitis ADReCS
Iritis ADReCS
Itch MetaADEDB
Keratitis ADReCS
Lacrimation Increased ADReCS
Leucopenia MetaADEDB
Leukaemic Infiltration Brain MetaADEDB
Limbal Hyperaemia ADReCS
Lymphocyte Count Decreased MetaADEDB
Lymphocyte Morphology Abnormal MetaADEDB
Macular Oedema ADReCS
Meningitis Fungal MetaADEDB
Mental Disorder MetaADEDB
Metastases To Liver MetaADEDB
Morphea MetaADEDB
Mouth Bleeding MetaADEDB
Myoglobin Blood Increased MetaADEDB
Nail Dystrophy MetaADEDB
Oedema ADReCS
Oesophageal Candidiasis MetaADEDB
Optic Nerve Disorder ADReCS
Optic Nerve Injury ADReCS
Palmar-Plantar Erythrodysaesthesia Syndrome MetaADEDB
Paronychia MetaADEDB
Photophobia ADReCS
Pigmentation Disorder ADReCS
Pineal Neoplasm MetaADEDB
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pneumocystis Jiroveci Pneumonia MetaADEDB
Poriomania MetaADEDB
Posterior Capsule Opacification ADReCS
Protein Total Decreased MetaADEDB
Pruritus ADReCS
Punctate Keratitis ADReCS
Pupillary Disorder MetaADEDB
Pyelonephritis MetaADEDB
Rash Generalised MetaADEDB
Renal Abscess MetaADEDB
Respiratory Rate Increased MetaADEDB
Rhagades MetaADEDB
Scab ADReCS
Scleral Disorder ADReCS
Scleral Hyperaemia ADReCS
Scleroderma MetaADEDB
Sensation Of Foreign Body ADReCS
Skin Depigmentation MetaADEDB
Skin Desquamation MetaADEDB
Skin Discolouration ADReCS
Skin Erosion MetaADEDB
Skin Laceration MetaADEDB
Skin Striae ADReCS
Splenic Abscess MetaADEDB
Uveitis ADReCS
Ventricular Drainage MetaADEDB
Vision Blurred ADReCS
Visual Acuity Reduced ADReCS
Visual Field Defect ADReCS
Vitreous Haemorrhage MetaADEDB
Wheeze MetaADEDB

InAADR: Drug-Protein-ADRs database