InAADR

Drug Information

Drug Name: Ixabepilone (219989-84-1)
PubChem ID: 6445540
SMILES: C[C@H]1CCC[C@@]2([C@@H](O2)C[C@H](NC(=O)C[C@@H](C(C(=O)[C@@H]([C@H]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C)C
InchiKey: FABUFPQFXZVHFB-PVYNADRNSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 506.709
LogP: 4.05052
Ring Count: 1
Hydrogen Bond Acceptor Count: 7
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 112.05

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Abscess MetaADEDB
Abdominal Mass MetaADEDB
Abdominal Pain ADReCS
Accident MetaADEDB
Aching Muscles MetaADEDB
Acid Reflux MetaADEDB
Acquired Dysfibrinogenaemia MetaADEDB
Acute Hepatic Failure ADReCS
Acute Kidney Failure MetaADEDB
Acute Pulmonary Oedema ADReCS
Administration Site Pain MetaADEDB
Afib MetaADEDB
Alopecia ADReCS
Amoebiasis MetaADEDB
Anaemia ADReCS
Anaesthesia MetaADEDB
Anal Abscess MetaADEDB
Angina Pectoris ADReCS
Anhedonia MetaADEDB
Anorexia ADReCS
Aphagia MetaADEDB
Appendicitis Perforated MetaADEDB
Arrhythmia Supraventricular ADReCS
Arterial Pressure Nos Decreased MetaADEDB
Arthralgia ADReCS
Aspartate Aminotransferase Increase MetaADEDB
Asthenia ADReCS
Asystole MetaADEDB
Atelectasis MetaADEDB
Atrial Flutter ADReCS
Atrial Tachycardia MetaADEDB
Autonomic Neuropathy MetaADEDB
Bacteraemia MetaADEDB
Bacteria Urine Identified MetaADEDB
Bacterial Infection ADReCS
Bacterial Pneumonia MetaADEDB
Bacterial Toxaemia MetaADEDB
Bladder Retention MetaADEDB
Blood Albumin Increased MetaADEDB
Blood Alkaline Phosphatase Increased ADReCS
Blood Calcium MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Culture Positive MetaADEDB
Blood Disorder MetaADEDB
Blood Sodium MetaADEDB
Blood Uric Acid MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Marrow Toxicity MetaADEDB
Breast Cancer Metastatic MetaADEDB
Bronchiectasis MetaADEDB
Bundle Branch Block Right MetaADEDB
Burning Sensation Mucosal MetaADEDB
Cancer Pain MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Tamponade MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Cardiomyopathy ADReCS
Cardiopulmonary Failure MetaADEDB
Central Venous Catheterisation MetaADEDB
Cerebral Haemorrhage ADReCS
Cerebral Ischaemia MetaADEDB
Cervicitis MetaADEDB
Chest Discomfort ADReCS
Chest Pain ADReCS
Chest Tube Insertion MetaADEDB
Chill MetaADEDB
Chills ADReCS
Choking Sensation MetaADEDB
Cholecystitis MetaADEDB
Clostridium Colitis MetaADEDB
Coagulopathy ADReCS
Cognitive Disorder ADReCS
Colitis ADReCS
Coma MetaADEDB
Complicated Migraine MetaADEDB
Connective Tissue Disorder ADReCS
Constipation ADReCS
Convulsions Grand Mal MetaADEDB
Coordination Abnormal ADReCS
Cough ADReCS
Deafness Bilateral MetaADEDB
Death MetaADEDB
Decreased Appetite ADReCS
Dehydration ADReCS
Demyelination MetaADEDB
Dental Caries MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitis Bullous MetaADEDB
Dermatitis Exfoliative MetaADEDB
Device Failure MetaADEDB
Diarrhea MetaADEDB
Diarrhoea ADReCS
Disseminated Intravascular Coagulation MetaADEDB
Dizziness ADReCS
Drowsiness MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dysaesthesia ADReCS
Dysgeusia ADReCS
Dysphagia ADReCS
Dysphonia ADReCS
Dyspnoea ADReCS
Dysuria MetaADEDB
Ecchymoses MetaADEDB
Electrolyte Disorder MetaADEDB
Embolism ADReCS
Embolism Pulmonary MetaADEDB
Emesis MetaADEDB
Encephalopathy MetaADEDB
Enlarged Liver MetaADEDB
Enterococcal Infection MetaADEDB
Enterocolitis ADReCS
Erosive Gastritis MetaADEDB
Erythema Multiforme ADReCS
Escherichia Bacteraemia MetaADEDB
Excess Potassium MetaADEDB
Fatigue MetaADEDB
Febrile Bone Marrow Aplasia MetaADEDB
Febrile Neutropenia ADReCS
Feeding Tube Complication MetaADEDB
Fluid Intake Reduced MetaADEDB
Fluid Overload MetaADEDB
Fractured Pelvis Nos MetaADEDB
Fungaemia MetaADEDB
Fungal Disease MetaADEDB
Gamma-Glutamyltransferase Increased ADReCS
Gastritis ADReCS
Gastrointestinal Bleed MetaADEDB
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Pain ADReCS
Gastrooesophageal Reflux Disease ADReCS
General Physical Health Deterioration MetaADEDB
Granulocytosis MetaADEDB
Haemorrhage ADReCS
Haemothorax MetaADEDB
Headache ADReCS
High Blood Pressure MetaADEDB
Hot Flush ADReCS
Hypersensitivity ADReCS
Hypoalbuminaemia MetaADEDB
Hypokalaemia ADReCS
Hypomagnesaemia MetaADEDB
Hyponatraemia ADReCS
Hypophosphataemia MetaADEDB
Hypotension ADReCS
Hypotension Orthostatic MetaADEDB
Hypothyroid MetaADEDB
Hypovolaemia ADReCS
Hypovolaemic Shock ADReCS
Hypoxia ADReCS
Hysterectomy MetaADEDB
Ileus ADReCS
Impaired Gastric Emptying ADReCS
Incontinence MetaADEDB
Infection ADReCS
Insomnia ADReCS
Intestinal Perforation MetaADEDB
Intra-Abdominal Haemorrhage MetaADEDB
Jaundice ADReCS
Kidney Failure MetaADEDB
Lacrimation Increased ADReCS
Large Intestine Perforation MetaADEDB
Laryngitis ADReCS
Laryngospasm MetaADEDB
Left Ventricular Dysfunction ADReCS
Lethargy ADReCS
Leucopenia MetaADEDB
Leukopenia ADReCS
Leukopenia Neonatal MetaADEDB
Loss Of Weight MetaADEDB
Lower Gastrointestinal Haemorrhage MetaADEDB
Lower Respiratory Tract Infection ADReCS
Lung Infiltration MetaADEDB
Lymphocele MetaADEDB
Lymphocytes Decreased MetaADEDB
Lymphopenia ADReCS
Malignant Pleural Effusion MetaADEDB
Metabolic Acidosis ADReCS
Metabolic Encephalopathy MetaADEDB
Metaplasia MetaADEDB
Metastases To Central Nervous System MetaADEDB
Metastases To Chest Wall MetaADEDB
Metastases To Liver MetaADEDB
Metastases To Spine MetaADEDB
Mucosal Inflammation MetaADEDB
Multi-Organ Failure MetaADEDB
Muscle Spasms ADReCS
Muscular Weakness ADReCS
Musculoskeletal Chest Pain MetaADEDB
Musculoskeletal Pain ADReCS
Myelosuppression SIDER
Myocardial Infarction ADReCS
Myocardial Ischaemia ADReCS
Nail Disorder ADReCS
Nausea ADReCS
Nephrolithiasis ADReCS
Nervous Tension MetaADEDB
Neumonia MetaADEDB
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Neutropenia ADReCS
Neutropenic Infection ADReCS
Neutrophil Count Decreased MetaADEDB
Odynophagia MetaADEDB
Oedema ADReCS
Oedema Mouth MetaADEDB
Oesophagitis ADReCS
Oliguria MetaADEDB
Oophorectomy Bilateral MetaADEDB
Oropharyngeal Pain ADReCS
Osteopenia MetaADEDB
Pain ADReCS
Palmar-Plantar Erythrodysaesthesia Syndrome ADReCS
Pancytopenia ADReCS
Panic Attack MetaADEDB
Pericardial Drainage MetaADEDB
Pericardial Effusion MetaADEDB
Pericardial Excision MetaADEDB
Peripheral Motor Neuropathy ADReCS
Peripheral Sensory Neuropathy ADReCS
Platelet Count MetaADEDB
Pleural Effusion MetaADEDB
Pneumococcal Infection MetaADEDB
Pneumonia ADReCS
Pneumonia Fungal MetaADEDB
Pneumonia Staphylococcal MetaADEDB
Pneumonitis ADReCS
Pneumoperitoneum MetaADEDB
Pneumothorax MetaADEDB
Productive Cough MetaADEDB
Pruritus ADReCS
Pulmonary Arrest MetaADEDB
Pyrexia ADReCS
Rash ADReCS
Recall Phenomenon ADReCS
Renal Failure ADReCS
Respiratory Failure ADReCS
Respiratory Rate Increased MetaADEDB
Right Heart Failure MetaADEDB
Risus Sardonicus MetaADEDB
Sepsis ADReCS
Septic Shock MetaADEDB
Skin Desquamation MetaADEDB
Skin Exfoliation ADReCS
Skin Hyperpigmentation ADReCS
Sleep Disorder MetaADEDB
Small Intestinal Obstruction MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Syncope ADReCS
Thoracotomy MetaADEDB
Thrombin Time Prolonged MetaADEDB
Thrombocytopenia ADReCS
Thrombosis ADReCS
Thyroid Cancer MetaADEDB
Tonsil Cancer MetaADEDB
Tooth Infection MetaADEDB
Transaminases Increased ADReCS
Trismus ADReCS
Tumour Ulceration MetaADEDB
Unresponsive To Stimuli MetaADEDB
Upper Respiratory Tract Infection ADReCS
Urinary Tract Infection ADReCS
Urinary Tract Infection Enterococcal MetaADEDB
Vasculitis ADReCS
Ventricular Fibrillation MetaADEDB
Vomiting ADReCS
Vulvar Erosion MetaADEDB
Weight Decreased ADReCS
Wrist Fracture MetaADEDB

InAADR: Drug-Protein-ADRs database