InAADR

Drug Information

Drug Name: Gliclazide (21187-98-4)
PubChem ID: 3475
SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN2CC3CCCC3C2
InchiKey: BOVGTQGAOIONJV-UHFFFAOYSA-N
Therapeutic Category: Hypoglycemic Agents

Computed Drug Properties

Molecular Weight (dalton): 323.418
LogP: 1.62982
Ring Count: 1
Hydrogen Bond Acceptor Count: 4
Hydrogen Bond Donor Count: 2
Total Polar Surface Area: 78.51

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort ADReCS
Abdominal Distension ADReCS
Abdominal Pain ADReCS
Abdominal Rigidity MetaADEDB
Abdominal Tenderness MetaADEDB
Abnormal Gait MetaADEDB
Abnormal Sensation In Eye MetaADEDB
Ache SIDER
Acidosis MetaADEDB
Acute Coronary Syndrome ADReCS
Acute Generalised Exanthematous Pustulosis MetaADEDB
Acute Glomerulonephritis MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Myocardial Infarction MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adynamic Ileus MetaADEDB
Agranulocytosis ADReCS
Albuminuria ADReCS
Allergic Cutaneous Angiitis SIDER
Alveolitis MetaADEDB
Anaemia ADReCS
Anaesthesia MetaADEDB
Anal Fissure ADReCS
Angina MetaADEDB
Angina Pectoris ADReCS
Anorexia MetaADEDB
Anti-Neutrophil Cytoplasmic Antibody Positive Vasculitis MetaADEDB
Antisocial Behaviour MetaADEDB
Anxiety ADReCS
Apathy MetaADEDB
Aphasia MetaADEDB
Arterial Disorder ADReCS
Arterial Stenosis MetaADEDB
Arterial Stent Insertion MetaADEDB
Arteritis ADReCS
Arthralgia ADReCS
Arthritis ADReCS
Arthropathy ADReCS
Asthenia ADReCS
Asthma ADReCS
Atrioventricular Block Complete MetaADEDB
Attention Deficit/Hyperactivity Disorder MetaADEDB
Automatism MetaADEDB
Azotemia MetaADEDB
B-Cell Lymphoma MetaADEDB
Back Pain ADReCS
Bacterial Corneal Ulcer MetaADEDB
Bacterial Toxaemia MetaADEDB
Balanoposthitis ADReCS
Belching MetaADEDB
Benign Breast Neoplasm ADReCS
Benign Colonic Neoplasm MetaADEDB
Benign Gastrointestinal Neoplasm SIDER
Bile Duct Obstruction MetaADEDB
Bladder Pain ADReCS
Bleeding Gums MetaADEDB
Blindness ADReCS
Blood Chloride Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Glucose Abnormal MetaADEDB
Blood Glucose Decreased MetaADEDB
Blood Lactate Dehydrogenase Increased MetaADEDB
Blood Ph Decreased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Sodium MetaADEDB
Blood Triglycerides Increased ADReCS
Blood Urea Abnormal MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Body Temperature Increased ADReCS
Bone Pain ADReCS
Brain Damage MetaADEDB
Breast Disorder Female ADReCS
Breast Neoplasm ADReCS
Breast Neoplasm Benign Female SIDER
Bronchitis ADReCS
Bronchopneumonia MetaADEDB
Burn Oesophageal MetaADEDB
Burning Sensation Mucosal MetaADEDB
Bursitis ADReCS
Calculus Of Kidney SIDER
Cancer MetaADEDB
Candida Endophthalmitis MetaADEDB
Carcinoma SIDER
Cardiac Disorder ADReCS
Cardiac Failure ADReCS
Cardiac Failure Acute MetaADEDB
Cardiac Flutter MetaADEDB
Cardiac Ischemia MetaADEDB
Cardio-Respiratory Arrest MetaADEDB
Carpal Tunnel Syndrome ADReCS
Cataract ADReCS
Cellulitis Orbital MetaADEDB
Central Nervous System Disorder SIDER
Cerebral Vascular Disorder MetaADEDB
Cerebrovascular Accident ADReCS
Cerebrovascular Disorder ADReCS
Chest Infection MetaADEDB
Chest Pain ADReCS
Chest X-Ray Abnormal MetaADEDB
Cholangiolitis MetaADEDB
Cholestasis ADReCS
Choroidal Dystrophy MetaADEDB
Chronic Left Ventricular Failure MetaADEDB
Colitis ADReCS
Colon Adenoma MetaADEDB
Colorectal Cancer Metastatic MetaADEDB
Coma ADReCS
Confusional State ADReCS
Congenital Anomaly ADReCS
Conjunctival Deposit MetaADEDB
Conjunctival Haemorrhage ADReCS
Conjunctivitis ADReCS
Conjunctivitis Allergic MetaADEDB
Constipation ADReCS
Coronary Artery Disease ADReCS
Coronary Heart Disease SIDER
Cough ADReCS
Coughing Blood MetaADEDB
Crackles Lung MetaADEDB
Crocodile Tears Syndrome ADReCS
Csf Neutrophil Count Increased MetaADEDB
Cyst ADReCS
Cystitis ADReCS
Cystitis Noninfective ADReCS
Deafness ADReCS
Dehydration MetaADEDB
Depressed Level Of Consciousness MetaADEDB
Dermatitis ADReCS
Dermatitis Bullous MetaADEDB
Dermatitis Exfoliative MetaADEDB
Developmental Delay ADReCS
Diabetes MetaADEDB
Diabetes Mellitus Inadequate Control MetaADEDB
Diabetes Mellitus Type 2 MetaADEDB
Dialysis MetaADEDB
Diarrhoea ADReCS
Diastolic Dysfunction MetaADEDB
Digestion Impaired SIDER
Diplopia ADReCS
Discomfort ADReCS
Disorder Lung MetaADEDB
Disorder Renal MetaADEDB
Disseminated Intravascular Coagulation MetaADEDB
Diverticular Perforation MetaADEDB
Dizziness ADReCS
Drowsiness SIDER
Drug Resistance MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dry Mouth ADReCS
Dry Skin ADReCS
Dry Throat MetaADEDB
Duodenal Ulcer ADReCS
Dyspepsia ADReCS
Dyspnoea ADReCS
Ear Infection ADReCS
Eczema ADReCS
Edema MetaADEDB
Electrocardiogram T Wave Inversion MetaADEDB
Elevated Triglycerides MetaADEDB
Emesis MetaADEDB
Eosinophil Count Increased MetaADEDB
Epigastric Fullness SIDER
Epistaxis ADReCS
Erectile Dysfunction ADReCS
Erythema ADReCS
Erythropenia ADReCS
Excess Potassium MetaADEDB
Eye Oedema MetaADEDB
Eye Redness MetaADEDB
Facial Palsy MetaADEDB
Faecal Incontinence ADReCS
Fatigue ADReCS
Feeling Abnormal ADReCS
Feeling Cold MetaADEDB
Femoral Neck Fracture MetaADEDB
Fibroma MetaADEDB
Flatulence ADReCS
Foreign Body Trauma MetaADEDB
Fungal Infection ADReCS
Fungal Skin Infection ADReCS
Gastric Antral Vascular Ectasia MetaADEDB
Gastric Cancer MetaADEDB
Gastric Hyperplasia MetaADEDB
Gastric Irritation SIDER
Gastric Ulcer Perforated MetaADEDB
Gastric Ulcer Surgery MetaADEDB
Gastritis ADReCS
Gastroenteritis ADReCS
Gastrointestinal Disorder ADReCS
Gastrointestinal Disturbance ADReCS
Gastrointestinal Infection MetaADEDB
Gastrointestinal Neoplasm ADReCS
Gastrointestinal Pain ADReCS
Gastrooesophageal Reflux Disease ADReCS
Gastrostomy Tube Insertion MetaADEDB
Gaze Palsy MetaADEDB
General Physical Health Deterioration MetaADEDB
Glaucoma ADReCS
Glucose Urine MetaADEDB
Glycosuria ADReCS
Goiter MetaADEDB
Gout ADReCS
Granuloma MetaADEDB
Haematoma MetaADEDB
Haemoglobin ADReCS
Haemolysis MetaADEDB
Haemolytic Anaemia ADReCS
Haemorrhage ADReCS
Haemorrhage Subcutaneous MetaADEDB
Haemorrhoids ADReCS
Headache ADReCS
Hearing Impaired ADReCS
Heart Valve Calcification MetaADEDB
Hemiplegia MetaADEDB
Henoch-Schonlein Purpura MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Failure ADReCS
Hepatic Fibrosis MetaADEDB
Hepatic Impairment ADReCS
Hepatitis ADReCS
Hepatocellular Damage MetaADEDB
Hepatomegaly ADReCS
Hernia ADReCS
Hernia Congenital ADReCS
Herpes Virus Infection MetaADEDB
Hypercholesterolaemia ADReCS
Hyperglycemia MetaADEDB
Hyperhidrosis ADReCS
Hyperinsulinism MetaADEDB
Hyperkeratosis ADReCS
Hyperlipidaemia ADReCS
Hyperparathyroidism MetaADEDB
Hyperprolactinaemia MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertriglyceridaemia ADReCS
Hypoglycaemia ADReCS
Hypoglycaemia Neonatal MetaADEDB
Hypoglycaemic Coma ADReCS
Hypoglycaemic Episode SIDER
Hypophosphataemia MetaADEDB
Hypopituitarism ADReCS
Hypopyon MetaADEDB
Hypotension ADReCS
Hypothyroidism ADReCS
Hypovolaemic Shock MetaADEDB
Iatrogenic Injury MetaADEDB
Ill-Defined Disorder ADReCS
Incontinence ADReCS
Increased Appetite ADReCS
Increased Platelet Count MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infarction ADReCS
Infection ADReCS
Infection In An Immunocompromised Host MetaADEDB
Insomnia ADReCS
Insufficiency Renal SIDER
Intestinal Obstruction MetaADEDB
Iritis MetaADEDB
Jaundice ADReCS
Jaundice Cholestatic ADReCS
Kidney Failure MetaADEDB
Kidney Pain MetaADEDB
Lacrimation SIDER
Lacrimation Increased ADReCS
Left Ventricular Dysfunction MetaADEDB
Left Ventricular Hypertrophy MetaADEDB
Leg Amputation MetaADEDB
Leg Edema SIDER
Leg Pain ADReCS
Lethargy MetaADEDB
Leukocytoclastic Vasculitis ADReCS
Leukopenia ADReCS
Lipid Metabolism Disorder ADReCS
Liver Disorder ADReCS
Loss Of Control Of Legs MetaADEDB
Lung Fibrosis MetaADEDB
Macula Lutea Degeneration MetaADEDB
Malaise ADReCS
Malnutrition ADReCS
Mastitis ADReCS
Melaena ADReCS
Menstrual Disorder ADReCS
Mental Disorder SIDER
Mental Impairment MetaADEDB
Metabolic Disorder SIDER
Micturition Urgency MetaADEDB
Mixed Hepatocellular-Cholestatic Injury MetaADEDB
Multi-Organ Failure MetaADEDB
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Mycobacterium Tuberculosis Infection MetaADEDB
Mycosis Fungoides MetaADEDB
Myelodysplasia MetaADEDB
Myelopathy MetaADEDB
Myocardial Infarction ADReCS
Nail Disorder ADReCS
Nausea ADReCS
Neoplasm ADReCS
Neoplasm Malignant ADReCS
Neoplasm Progression MetaADEDB
Nephrolithiasis ADReCS
Nephropathy ADReCS
Nervous System Disorder SIDER
Nervousness ADReCS
Neumonia MetaADEDB
Neuralgia ADReCS
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Nocturia ADReCS
Oedema ADReCS
Oedema Peripheral ADReCS
Oesophagitis ADReCS
Oliguria MetaADEDB
Onychomadesis MetaADEDB
Onychomycosis ADReCS
Orthopnea MetaADEDB
Osteoarthritis ADReCS
Otitis SIDER
Otitis Media ADReCS
Overdose MetaADEDB
Pain ADReCS
Pain In Extremity ADReCS
Pallor MetaADEDB
Palpitations ADReCS
Pancreatic Cancer MetaADEDB
Pancreatitis ADReCS
Pancreatitis Acute ADReCS
Pancytopenia ADReCS
Paraesthesia ADReCS
Paranoia MetaADEDB
Paraparesis MetaADEDB
Paraplegia MetaADEDB
Peritonitis Bacterial MetaADEDB
Petechia MetaADEDB
Pharyngitis ADReCS
Photosensitivity SIDER
Photosensitivity Reaction ADReCS
Platelet Count Abnormal MetaADEDB
Pneumocystis Jiroveci Infection MetaADEDB
Pneumonia ADReCS
Polyp MetaADEDB
Polyuria ADReCS
Poor Quality Sleep MetaADEDB
Porphyria ADReCS
Porphyria Hepatic SIDER
Porphyria Non-Acute SIDER
Post Thrombotic Syndrome MetaADEDB
Prostatic Disorder ADReCS
Pruritus ADReCS
Psoriasis MetaADEDB
Psoriatic Arthritis MetaADEDB
Punctate Keratitis MetaADEDB
Pyroglutamate Increased MetaADEDB
Pyuria MetaADEDB
Rash ADReCS
Rash Maculo-Papular ADReCS
Renal Cancer MetaADEDB
Renal Cyst ADReCS
Renal Failure ADReCS
Renal Failure Acute ADReCS
Renal Impairment MetaADEDB
Renal Injury MetaADEDB
Renal Tubular Disorder MetaADEDB
Respiratory Tract Infection ADReCS
Retinal Bleeding MetaADEDB
Retinal Disorder ADReCS
Retinal Vein Occlusion MetaADEDB
Rhinitis ADReCS
Salivary Hypersecretion ADReCS
Salmonella Sepsis MetaADEDB
Secondary Hypothyroidism MetaADEDB
Sensation Of Heaviness MetaADEDB
Sepsis Syndrome MetaADEDB
Septic Shock MetaADEDB
Shakiness SIDER
Shift To The Left MetaADEDB
Shock Haemorrhagic MetaADEDB
Sinusitis ADReCS
Skin Desquamation MetaADEDB
Skin Disorder ADReCS
Skin Ulcer ADReCS
Somnolence ADReCS
Spine Malformation ADReCS
Spinning Sensation MetaADEDB
Sputum Discoloured MetaADEDB
Sudden Death MetaADEDB
Superficial Thrombophlebitis MetaADEDB
Sweating SIDER
Tachycardia ADReCS
Tardive Dyskinesia MetaADEDB
Tendon Rupture MetaADEDB
Tendonitis ADReCS
Tension ADReCS
Thirst ADReCS
Thrombocytopenia ADReCS
Thrombophlebitis ADReCS
Thyroiditis Acute MetaADEDB
Tinnitus ADReCS
Tooth Disorder ADReCS
Toothache ADReCS
Toxic Skin Eruption MetaADEDB
Tracheitis ADReCS
Tremor ADReCS
Tumour Lysis Syndrome MetaADEDB
Ulcer ADReCS
Upper Respiratory Tract Infection ADReCS
Urinary Tract Infection ADReCS
Urine Output Increased ADReCS
Urticaria ADReCS
Urticaria Generalised MetaADEDB
Vaginal Infection ADReCS
Vaginal Inflammation ADReCS
Vasculitis ADReCS
Vein Disorder ADReCS
Viral Infection ADReCS
Visual Acuity Reduced ADReCS
Visual Impairment ADReCS
Vitreous Detachment MetaADEDB
Vitreous Disorder ADReCS
Vitreous Haemorrhage MetaADEDB
Vomiting ADReCS
Weakness SIDER
Weight Increased ADReCS
Wheeze MetaADEDB
Xerophthalmia ADReCS

InAADR: Drug-Protein-ADRs database