InAADR

Drug Information

Drug Name: Nalbuphine (20594-83-6)
PubChem ID: 5311304
SMILES: C1CC(C1)CN2CC[C@]34[C@@H]5[C@H](CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O)O
InchiKey: NETZHAKZCGBWSS-CEDHKZHLSA-N
Therapeutic Category: Analgesics, Central Nervous System Agents, Central Nervous System Depressants, Narcotic Antagonists, Narcotics, Peripheral Nervous System Agents, Sensory System Agents

Computed Drug Properties

Molecular Weight (dalton): 357.45
LogP: 1.7073
Ring Count: 1
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 3
Total Polar Surface Area: 73.16

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Cramp ADReCS
Abdominal Discomfort MetaADEDB
Abdominal Pain ADReCS
Abdominal Pain MetaADEDB
Abnormal Dreams ADReCS
Abnormal Movements MetaADEDB
Abnormal Sensation In Eye MetaADEDB
Abnormal Vision MetaADEDB
Abscess MetaADEDB
Accelerated Hypertension MetaADEDB
Accident MetaADEDB
Accidental Overdose MetaADEDB
Aching Joints MetaADEDB
Acidosis MetaADEDB
Activated Partial Thromboplastin Time Prolonged MetaADEDB
Acute Kidney Failure MetaADEDB
Acute Otitis Media MetaADEDB
Acute Pulmonary Oedema MetaADEDB
Acute Respiratory Distress Syndrome MetaADEDB
Adenopathy MetaADEDB
Adhesion MetaADEDB
Adverse Drug Effect MetaADEDB
Aggression MetaADEDB
Agitated MetaADEDB
Agitation ADReCS
Alopecia MetaADEDB
Amentia MetaADEDB
Anaemia MetaADEDB
Anaesthesia MetaADEDB
Anaphylactic Reaction ADReCS
Androgen Deficiency MetaADEDB
Anemia Sickle Cell MetaADEDB
Aneurysm MetaADEDB
Angiitis MetaADEDB
Angioedema MetaADEDB
Anoxic Encephalopathy MetaADEDB
Anuria MetaADEDB
Anxiety ADReCS
Aortic Disorder MetaADEDB
Aphakia MetaADEDB
Aphthous Stomatitis MetaADEDB
Apnea MetaADEDB
Appendicitis Perforated MetaADEDB
Application Site Erythema MetaADEDB
Application Site Hypersensitivity MetaADEDB
Areflexia MetaADEDB
Arterial Pressure Nos Decreased MetaADEDB
Arteriosclerosis MetaADEDB
Arthritis Rheumatoid MetaADEDB
Aspergillosis MetaADEDB
Asphyxia MetaADEDB
Asthenia ADReCS
Asthma ADReCS
Atrial Ectopic Beats MetaADEDB
Atrial Septal Defect MetaADEDB
Atrial Tachycardia MetaADEDB
Atrophy MetaADEDB
Autoimmune Thyroiditis MetaADEDB
Autologous Bone Marrow Transplantation Therapy MetaADEDB
Back Ache MetaADEDB
Bacteraemia MetaADEDB
Bacterial Toxaemia MetaADEDB
Bile Duct Stone MetaADEDB
Bipolar Ii Disorder MetaADEDB
Birth Trauma MetaADEDB
Bladder Neck Obstruction MetaADEDB
Bladder Retention MetaADEDB
Bleeding Gums MetaADEDB
Blepharoptosis MetaADEDB
Blood Albumin Decreased MetaADEDB
Blood Alkaline Phosphatase Increased MetaADEDB
Blood Calcium MetaADEDB
Blood Count Abnormal MetaADEDB
Blood Creatine Increased MetaADEDB
Blood Creatinine Increased MetaADEDB
Blood Fibrinogen Increased MetaADEDB
Blood Gases Abnormal MetaADEDB
Blood Homocysteine MetaADEDB
Blood In Urine MetaADEDB
Blood Magnesium Decreased MetaADEDB
Blood Methanol Increased MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Pressure Systolic Decreased MetaADEDB
Blood Sodium MetaADEDB
Blood Urea Increased MetaADEDB
Blood Uric Acid MetaADEDB
Bloody Discharge MetaADEDB
Body Temperature Increased ADReCS
Bone Cancer Metastatic MetaADEDB
Bone Cyst MetaADEDB
Bone Disorder MetaADEDB
Bone Fragmentation MetaADEDB
Bone Inflammation MetaADEDB
Bone Lesion MetaADEDB
Bone Marrow Failure MetaADEDB
Bone Neoplasm Malignant MetaADEDB
Bradycardia ADReCS
Bradycardia Neonatal MetaADEDB
Bradypnoea MetaADEDB
Brain Damage MetaADEDB
Brain Oedema MetaADEDB
Brief Psychotic Disorder With Postpartum Onset MetaADEDB
Bronchospasm ADReCS
Bruise MetaADEDB
Bulging MetaADEDB
Burning Sensation ADReCS
Caesarean Section MetaADEDB
Candidiasis Of Mouth MetaADEDB
Carcinoma Of The Colon MetaADEDB
Cardiac Arrest ADReCS
Cardiac Decompensation MetaADEDB
Cardiac Enlargement MetaADEDB
Cardiac Failure MetaADEDB
Cardiac Murmur MetaADEDB
Cataract Operation MetaADEDB
Central Venous Catheterisation MetaADEDB
Cerebral Infarct MetaADEDB
Cerebral Palsy MetaADEDB
Cerebral Thrombosis MetaADEDB
Cerebral Venous Thrombosis MetaADEDB
Cervicalgia MetaADEDB
Chest Pain MetaADEDB
Chill MetaADEDB
Choking Sensation MetaADEDB
Cholecystitis Chronic MetaADEDB
Cholestasis MetaADEDB
Cholesterosis MetaADEDB
Chorioamnionitis MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Sinusitis MetaADEDB
Circumstance Or Information Capable Of Leading To Medication Error MetaADEDB
Closed Head Injury MetaADEDB
Coagulation Time Prolonged MetaADEDB
Cocaine-Related Disorders MetaADEDB
Cold Sweat ADReCS
Colon Spastic MetaADEDB
Colonic Polyp MetaADEDB
Coma MetaADEDB
Complications Of Maternal Exposure To Therapeutic Drugs MetaADEDB
Confabulation MetaADEDB
Confusional State ADReCS
Congenital Nystagmus MetaADEDB
Congenital Tricuspid Valve Incompetence MetaADEDB
Congenital Ventricular Septal Defect MetaADEDB
Contracture MetaADEDB
Convulsion ADReCS
Convulsions Grand Mal MetaADEDB
Coombs Indirect Test Positive MetaADEDB
Cough MetaADEDB
Cramp Muscle SIDER
Creatinine Renal Clearance Decreased MetaADEDB
Crying ADReCS
Csf Protein MetaADEDB
Cyanosis MetaADEDB
Cyanosis Neonatal MetaADEDB
Cyst MetaADEDB
Cytolytic Hepatitis MetaADEDB
Deafness Congenital MetaADEDB
Death ADReCS
Death Neonatal MetaADEDB
Debridement MetaADEDB
Decreased Interest MetaADEDB
Deglutition Disorder MetaADEDB
Dehydration MetaADEDB
Delirium Tremens MetaADEDB
Delusion ADReCS
Demyelination MetaADEDB
Dental Abscess MetaADEDB
Dental Operation MetaADEDB
Dependence MetaADEDB
Depersonalisation ADReCS
Depressed Level Of Consciousness ADReCS
Depressed Mood MetaADEDB
Depression ADReCS
Derealisation ADReCS
Dermatitis ADReCS
Dermatosis MetaADEDB
Dermographism MetaADEDB
Detached Retina MetaADEDB
Device Breakage MetaADEDB
Device Related Infection MetaADEDB
Diabetes Mellitus Non-Insulin-Dependent MetaADEDB
Diplopia MetaADEDB
Disabled Relative MetaADEDB
Disturbance In Attention MetaADEDB
Diverticulitis MetaADEDB
Diverticulum MetaADEDB
Dizziness ADReCS
Drowsiness MetaADEDB
Drug Abuser MetaADEDB
Drug Addict MetaADEDB
Drug Exposure During Pregnancy MetaADEDB
Drug Exposure Via Breast Milk MetaADEDB
Drug Interaction MetaADEDB
Drug Withdrawal MetaADEDB
Drug Withdrawal Headache MetaADEDB
Dry Mouth ADReCS
Dysgeusia ADReCS
Dyslipidaemia MetaADEDB
Dyspepsia ADReCS
Dysphoria ADReCS
Dyspnoea ADReCS
Dyspnoea Paroxysmal Nocturnal MetaADEDB
Dysthymic Disorder MetaADEDB
Ecchymoses MetaADEDB
Eczema MetaADEDB
Electrocardiogram Qrs Complex Prolonged MetaADEDB
Encephalitis Allergic MetaADEDB
Encephalitis Toxic MetaADEDB
Endodontic Procedure MetaADEDB
Epistaxis MetaADEDB
Eruption MetaADEDB
Erythema ADReCS
Euphoric Mood ADReCS
Extrasystoles Ventricular MetaADEDB
Extremity Pain MetaADEDB
Eye Pain MetaADEDB
Facial Flushing MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue MetaADEDB
Fatty Liver MetaADEDB
Febrile Bone Marrow Aplasia MetaADEDB
Feeling Abnormal ADReCS
Feeling Hot ADReCS
Fib MetaADEDB
Fibromyalgia MetaADEDB
Flu MetaADEDB
Fluid Overload MetaADEDB
Flushing ADReCS
Foetal Distress Syndrome MetaADEDB
Foetal Heart Rate Deceleration MetaADEDB
Formication MetaADEDB
Gall Bladder MetaADEDB
Gastrointestinal Pain ADReCS
Glasgow Coma Scale MetaADEDB
Glucose Intolerance MetaADEDB
Goiter MetaADEDB
Granulocytosis MetaADEDB
Haematemesis MetaADEDB
Haematocrit Increased MetaADEDB
Haematoma MetaADEDB
Haemodialysis MetaADEDB
Haemoglobin Increased MetaADEDB
Haemorrhage Coronary Artery MetaADEDB
Haemorrhagic Transformation Stroke MetaADEDB
Hallucination ADReCS
Headache ADReCS
Heart Rate Increased MetaADEDB
Hemiparesis MetaADEDB
Hepatotoxicity ADReCS
Hip Fracture MetaADEDB
Hospitalisation MetaADEDB
Hostility ADReCS
Hot Flash MetaADEDB
Hydronephrosis MetaADEDB
Hyperalgesia MetaADEDB
Hyperammonaemia MetaADEDB
Hyperamylasaemia MetaADEDB
Hyperhidrosis ADReCS
Hyperlipasaemia MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertonia MetaADEDB
Hypoaesthesia ADReCS
Hypomagnesaemia MetaADEDB
Hypotension ADReCS
Hypotension Orthostatic MetaADEDB
Hypotonia MetaADEDB
Hypotonia Neonatal MetaADEDB
Hypoxia MetaADEDB
Idiopathic Thrombocytopenic Purpura MetaADEDB
Impaired Gastric Emptying MetaADEDB
Impaired Healing MetaADEDB
Incontinence MetaADEDB
Increased Platelet Count MetaADEDB
Increased White Blood Cell Count MetaADEDB
Infection Upper Respiratory MetaADEDB
Infection Urinary Tract MetaADEDB
Injection Site Irritation MetaADEDB
Injection Site Reaction ADReCS
Injury Of Neck MetaADEDB
Intention Tremor MetaADEDB
International Normalised Ratio Decreased MetaADEDB
International Normalised Ratio Increased MetaADEDB
Interstitial Nephritis MetaADEDB
Intervertebral Disc Degeneration MetaADEDB
Intra-abdominal haematoma MetaADEDB
Intra-Uterine Death ADReCS
Intracranial Aneurysm MetaADEDB
Intraocular Lens Implant MetaADEDB
Intraventricular Haemorrhage MetaADEDB
Iridocele MetaADEDB
Jaw Operation MetaADEDB
Joint Lock MetaADEDB
Kaolin Cephalin Clotting Time Prolonged MetaADEDB
Knee Arthroplasty MetaADEDB
Labor Pain MetaADEDB
Lacrimation Increased ADReCS
Laryngeal Disorder MetaADEDB
Laryngeal Oedema ADReCS
Left Atrial Dilatation MetaADEDB
Leg Amputation MetaADEDB
Lethargy MetaADEDB
Ligament Rupture MetaADEDB
Loss Of Consciousness ADReCS
Loss Of Weight MetaADEDB
Lung Edema MetaADEDB
Maculopathy MetaADEDB
Maternal Drugs Affecting Foetus MetaADEDB
Mean Arterial Pressure Decreased MetaADEDB
Meconium Stain MetaADEDB
Meningitides MetaADEDB
Mental Disorders MetaADEDB
Mental Retardation MetaADEDB
Metabolic Disorder MetaADEDB
Metastases To Central Nervous System MetaADEDB
Metastases To Meninges MetaADEDB
Micturition Urgency ADReCS
Migraine MetaADEDB
Morphine Dependence MetaADEDB
Motor Dysfunction MetaADEDB
Mouth Pain MetaADEDB
Movement Disorder MetaADEDB
Mucosal Inflammation MetaADEDB
Muscle Spasms ADReCS
Muscle Tightness MetaADEDB
Muscular Weakness ADReCS
Musculoskeletal Chest Pain MetaADEDB
Musculoskeletal Discomfort MetaADEDB
Musculoskeletal Pain MetaADEDB
Nasal Congestion MetaADEDB
Nasopharyngitis MetaADEDB
Nausea ADReCS
Near Syncope MetaADEDB
Neonatal Respiratory Arrest MetaADEDB
Nervous Tension MetaADEDB
Nervousness ADReCS
Neumonia MetaADEDB
Neuropathy Peripheral MetaADEDB
No Therapeutic Response MetaADEDB
Numbness SIDER
Obliterative Bronchiolitis MetaADEDB
Obstruction MetaADEDB
Ocular Discomfort MetaADEDB
Oedema ADReCS
Oral Polypectomy MetaADEDB
Osteoarthritis MetaADEDB
Osteomyelitis MetaADEDB
Osteosclerosis MetaADEDB
Ovarian Cyst MetaADEDB
Overdose MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Pain ADReCS
Pain Exacerbated MetaADEDB
Pain Postoperative MetaADEDB
Pallor MetaADEDB
Pancreatic Atrophy MetaADEDB
Pancreatic Haemorrhage MetaADEDB
Pancreatitis MetaADEDB
Pancreatitis Chronic MetaADEDB
Paraesthesia ADReCS
Pco2 Increased MetaADEDB
Penile Oedema MetaADEDB
Periodic Limb Movement Disorder MetaADEDB
Periventricular Leukomalacia MetaADEDB
Persistent Foetal Circulation MetaADEDB
Petechia MetaADEDB
Phlebitis MetaADEDB
Phlebothrombosis MetaADEDB
Phonophobia MetaADEDB
Photosensitive Rash MetaADEDB
Piloerection ADReCS
Placental Disorder MetaADEDB
Placental Infarction MetaADEDB
Placental Insufficiency MetaADEDB
Platelet Count MetaADEDB
Pleurisy MetaADEDB
Pneumothorax MetaADEDB
Pollakiuria ADReCS
Polysubstance Abuse MetaADEDB
Post Nasal Drip MetaADEDB
Post Procedural Complication MetaADEDB
Postoperative Nausea And Vomiting MetaADEDB
Premature Baby MetaADEDB
Premature Separation Of Placenta MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus ADReCS
Psychosomatic Disease MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Hypertension MetaADEDB
Pulmonary Oedema ADReCS
Pyrexia ADReCS
Rash ADReCS
Rash Generalised MetaADEDB
Red Blood Cell Count Increased MetaADEDB
Red Blood Cell Morphology MetaADEDB
Redness SIDER
Reflexes Abnormal MetaADEDB
Renal Infarct MetaADEDB
Renal Tubular Disorder MetaADEDB
Respiratory Arrest ADReCS
Respiratory Distress ADReCS
Respiratory Insufficiency MetaADEDB
Respiratory Rate Increased MetaADEDB
Restlessness ADReCS
Retroperitoneal Lymphadenopathy MetaADEDB
Rhinorrhoea ADReCS
Rib Fracture MetaADEDB
Right Atrial Dilatation MetaADEDB
Right Ventricular Hypertrophy MetaADEDB
Saccadic Eye Movement MetaADEDB
Sedation ADReCS
Seizures SIDER
Sensation Of Heaviness ADReCS
Sensory Loss ADReCS
Shakiness SIDER
Shock ADReCS
Sinoatrial Block MetaADEDB
Sinus Disorder MetaADEDB
Sinusitis MetaADEDB
Skeletal Injury MetaADEDB
Skin Injury MetaADEDB
Sleep Apnea MetaADEDB
Somnolence ADReCS
Spasm MetaADEDB
Speech Disorder ADReCS
Speech Impairment Nos SIDER
Sphincter Of Oddi Dysfunction MetaADEDB
Spinal Column Stenosis MetaADEDB
Spinal Cord Operation MetaADEDB
Spinal Disorder MetaADEDB
Spondylolisthesis MetaADEDB
Sputum Discoloured MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Stem Cell Transplant MetaADEDB
Stevens-Johnson Syndrome MetaADEDB
Sticky Skin ADReCS
Stridor ADReCS
Subarachnoid Haemorrhage MetaADEDB
Subdural Haemorrhage MetaADEDB
Substance Withdrawal Syndrome MetaADEDB
Sudden Death MetaADEDB
Superficial Thrombophlebitis MetaADEDB
Superior Sagittal Sinus Thrombosis MetaADEDB
Sweating Increased SIDER
Swelling ADReCS
Syncope ADReCS
Synovial Cyst MetaADEDB
Tachycardia ADReCS
Tachycardia Ventricular MetaADEDB
Taste Bitter ADReCS
Tendinitis MetaADEDB
Tension ADReCS
Testes Pain MetaADEDB
Throat Tightness MetaADEDB
Thyroid Disease MetaADEDB
Tingling Sensation SIDER
Tinnitus MetaADEDB
Tongue Biting MetaADEDB
Tooth Disease MetaADEDB
Toxoplasmosis MetaADEDB
Tremor ADReCS
Umbilical Cord Abnormality MetaADEDB
Unequal Limb Length MetaADEDB
Ureteral Stent Insertion MetaADEDB
Urticaria ADReCS
Uterine Contractions Abnormal MetaADEDB
Uterine Hypotonus MetaADEDB
Vaginal Haematoma MetaADEDB
Vena Cava Thrombosis MetaADEDB
Vertigo ADReCS
Vision Blurred ADReCS
Vocal Cord Paralysis MetaADEDB
Vomiting ADReCS
Weakness SIDER
Weight Gain Poor MetaADEDB
Wheezing ADReCS
White Blood Cell Count Abnormal MetaADEDB
Withdrawal Syndrome MetaADEDB

InAADR: Drug-Protein-ADRs database