InAADR

Drug Information

Drug Name: Memantine (19982-08-2)
PubChem ID: 4054
SMILES: CC12CC3CC(C1)(CC(C3)(C2)N)C
InchiKey: BUGYDGFZZOZRHP-UHFFFAOYSA-N
Therapeutic Category: Anti-Dyskinesia Agents, Antiparkinson Agents, Central Nervous System Agents, Dopamine Agents, Excitatory Amino Acid Agents, Excitatory Amino Acid Antagonists, Neurotransmitter Agents

Computed Drug Properties

Molecular Weight (dalton): 179.307
LogP: 2.6941
Ring Count: 0
Hydrogen Bond Acceptor Count: 1
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 26.02

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Adhesions MetaADEDB
Abdominal Pain ADReCS
Abnormal Dreams MetaADEDB
Abnormal Faeces MetaADEDB
Abnormal Gait ADReCS
Abuse MetaADEDB
Accidental Overdose MetaADEDB
Aching Joints MetaADEDB
Acid Reflux MetaADEDB
Acne ADReCS
Acute Coronary Syndrome ADReCS
Adnexitis MetaADEDB
Adrenal Insufficiency MetaADEDB
Adrenal Mass MetaADEDB
Affect Lability ADReCS
Aggression ADReCS
Aggressive Reaction SIDER
Agitated MetaADEDB
Agitation ADReCS
Agranulocytosis ADReCS
Alanine Aminotransferase Increased SIDER
Alcohol Interaction MetaADEDB
Allergic Reaction ADReCS
Alopecia ADReCS
Als MetaADEDB
Altered State Of Consciousness ADReCS
Alzheimer Disease MetaADEDB
Amnesia ADReCS
Anaemia ADReCS
Anal Cancer Metastatic MetaADEDB
Anemia Aplastic MetaADEDB
Anger MetaADEDB
Angina Pectoris ADReCS
Angiogram Abnormal MetaADEDB
Angiopathy ADReCS
Anhedonia MetaADEDB
Anorexia ADReCS
Anticoagulation Drug Level Above Therapeutic MetaADEDB
Anxiety ADReCS
Aortic Aneurysm SIDER
Aortic Calcification MetaADEDB
Aortic Dilatation MetaADEDB
Aortic Dissection SIDER
Apathy ADReCS
Aphasia ADReCS
Apnoea ADReCS
Appetite Disorder MetaADEDB
Application Site Ulcer MetaADEDB
Apraxia MetaADEDB
Arterial Stenosis MetaADEDB
Arthralgia ADReCS
Arthropod Bite MetaADEDB
Aspiration ADReCS
Asthenia ADReCS
Asthma ADReCS
Ataxia ADReCS
Atelectasis MetaADEDB
Atrial Fibrillation ADReCS
Atrioventricular Block ADReCS
Atrophy MetaADEDB
Aura MetaADEDB
Auricular Swelling MetaADEDB
Autistic Disorder MetaADEDB
Autonomic Neuropathy MetaADEDB
Azotaemia MetaADEDB
Back Pain ADReCS
Bacterial Sepsis MetaADEDB
Bad Breath MetaADEDB
Balance Disorder PROTECT
Band Neutrophil Count Increased MetaADEDB
Belligerence MetaADEDB
Bilirubin Conjugated Increased MetaADEDB
Birth Defect MetaADEDB
Bladder Adenocarcinoma Stage Unspecified MetaADEDB
Bladder Dilatation MetaADEDB
Bladder Discomfort MetaADEDB
Bladder Disorder MetaADEDB
Bladder Mass MetaADEDB
Bladder Prolapse MetaADEDB
Blepharitis ADReCS
Blood 125-Dihydroxycholecalciferol Decreased MetaADEDB
Blood Alkaline Phosphatase Increased ADReCS
Blood Cortisol Decreased MetaADEDB
Blood Creatinine Increased ADReCS
Blood Glucose Decreased MetaADEDB
Blood Iron Decreased MetaADEDB
Blurred Vision MetaADEDB
Body Fat Disorder MetaADEDB
Body Temperature Decreased ADReCS
Body Temperature Increased ADReCS
Bone Erosion MetaADEDB
Bone Marrow Transplant MetaADEDB
Bone Pain MetaADEDB
Bowel Movement Irregularity MetaADEDB
Bradycardia ADReCS
Brain Herniation MetaADEDB
Brain Mass MetaADEDB
Brain Natriuretic Peptide Decreased MetaADEDB
Breakthrough Bleeding MetaADEDB
Breast Cancer Metastatic MetaADEDB
Breast Discomfort MetaADEDB
Breast Dysplasia MetaADEDB
Breast Enlargement MetaADEDB
Breast Fibrosis MetaADEDB
Breast Necrosis MetaADEDB
Bronchitis ADReCS
Bruise MetaADEDB
Bundle Branch Block Left MetaADEDB
Capillary Disorder MetaADEDB
Carcinoid Syndrome MetaADEDB
Cardiac Arrest ADReCS
Cardiac Decompensation MetaADEDB
Cardiac Disorder ADReCS
Cardiac Enzymes Increased MetaADEDB
Cardiac Failure ADReCS
Cardiac Fibrillation ADReCS
Cardiac Hypertrophy MetaADEDB
Cardiac Valve Disease MetaADEDB
Cardioactive Drug Level Above Therapeutic MetaADEDB
Cardioactive Drug Level Increased MetaADEDB
Carpal Tunnel Syndrome ADReCS
Cartilage Development Disorder MetaADEDB
Catalepsy MetaADEDB
Cataract ADReCS
Cd4 Lymphocytes Increased MetaADEDB
Cellulitis ADReCS
Cerebral Haemorrhage ADReCS
Cerebral Infarction ADReCS
Cerebral Microangiopathy MetaADEDB
Cerebrovascular Accident ADReCS
Chapped Lips MetaADEDB
Chest Pain ADReCS
Cholelithiasis ADReCS
Cholestasis MetaADEDB
Chondropathy MetaADEDB
Chromaturia MetaADEDB
Chronic Hepatic Failure MetaADEDB
Chronic Kidney Disease MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Claudication SIDER
Clostridial Infection MetaADEDB
Cognitive Deterioration MetaADEDB
Colitis ADReCS
Colpitis MetaADEDB
Coma ADReCS
Completed Suicide ADReCS
Complication Of Device Insertion MetaADEDB
Confabulation MetaADEDB
Confusion MetaADEDB
Confusional State ADReCS
Congestive Cardiomyopathy MetaADEDB
Conjunctival Haemorrhage ADReCS
Conjunctivitis ADReCS
Connective Tissue Disorder SIDER
Constipated MetaADEDB
Constipation ADReCS
Convulsion ADReCS
Coordination Abnormal ADReCS
Corneal Opacity ADReCS
Costochondritis MetaADEDB
Cough ADReCS
Cramp MetaADEDB
Creatinine Increased SIDER
Crocodile Tears Syndrome ADReCS
Crying ADReCS
Crying Abnormal ADReCS
Cystocele MetaADEDB
Deafness ADReCS
Deafness Congenital MetaADEDB
Deafness Unilateral MetaADEDB
Death ADReCS
Decreased Appetite ADReCS
Decreased Libido MetaADEDB
Deep Vein Thrombosis ADReCS
Dehydration ADReCS
Delirium ADReCS
Delusion ADReCS
Dementia MetaADEDB
Dementia Vascular MetaADEDB
Dental Abscess MetaADEDB
Dental Caries MetaADEDB
Dental Operation MetaADEDB
Dental Pain MetaADEDB
Depersonalisation ADReCS
Depressed Level Of Consciousness ADReCS
Depression ADReCS
Dermatitides MetaADEDB
Dermatitis ADReCS
Detachment Psychological SIDER
Developmental Disabilities MetaADEDB
Device Malfunction MetaADEDB
Diabetes Mellitus ADReCS
Diabetic Retinopathy MetaADEDB
Diarrhoea ADReCS
Difficulty In Walking MetaADEDB
Diplopia ADReCS
Discomfort ADReCS
Disease Complication MetaADEDB
Disease Recurrence MetaADEDB
Disorientation ADReCS
Dissociation ADReCS
Disturbance In Sexual Arousal ADReCS
Diverticulitis ADReCS
Dizziness ADReCS
Drowsiness MetaADEDB
Drug Hypersensitivity PROTECT
Drug Withdrawal Headache MetaADEDB
Drug-Induced Liver Injury MetaADEDB
Dyskinesia ADReCS
Dyskinesia Drug-Induced MetaADEDB
Dyslexia MetaADEDB
Dysphagia ADReCS
Dyspnea Exertional MetaADEDB
Dyspnoea ADReCS
Dyspnoea Exacerbated MetaADEDB
Dysthymic Disorder MetaADEDB
Dysuria ADReCS
Ear Infection ADReCS
Easy Bruisability MetaADEDB
Economic Problem MetaADEDB
Eczema ADReCS
Edema Extremities MetaADEDB
Effusion MetaADEDB
Ejaculation Failure MetaADEDB
Electrocardiogram Change SIDER
Electrocardiogram Qt Prolonged ADReCS
Embolism ADReCS
Encephalopathy ADReCS
Endarterectomy MetaADEDB
Endocrine Disorder SIDER
Endotracheal Intubation Complication MetaADEDB
Energy Increased MetaADEDB
Enterobacter Infection MetaADEDB
Enuresis MetaADEDB
Eosinophil Percentage Increased MetaADEDB
Erectile Dysfunction ADReCS
Eruption MetaADEDB
Erythema Multiforme ADReCS
Essential Hypertension MetaADEDB
Excess Potassium MetaADEDB
Excessive Sleepiness MetaADEDB
Exercise Tolerance Decreased MetaADEDB
Extrapyramidal Disorder ADReCS
Eye Pain ADReCS
Eyelid Ptosis ADReCS
Eyelid Retraction MetaADEDB
Facial Nerve Disorder MetaADEDB
Faecal Incontinence ADReCS
Faeces Discoloured MetaADEDB
Failure Of Implant MetaADEDB
Failure To Thrive MetaADEDB
Fall ADReCS
Fatigue ADReCS
Feeling Abnormal ADReCS
Feeling Drunk MetaADEDB
Fibromyalgia MetaADEDB
Flat Affect ADReCS
Foaming At Mouth MetaADEDB
Food Craving MetaADEDB
Forearm Fracture MetaADEDB
Fracture ADReCS
Full Blood Count Decreased MetaADEDB
Fungal Infection PROTECT
Gait Disturbance ADReCS
Gallbladder Cancer MetaADEDB
Gastritis ADReCS
Gastroenteritis ADReCS
Gastrointestinal Disorder SIDER
Gastrointestinal Haemorrhage ADReCS
Gastrointestinal Pain ADReCS
Gastrooesophageal Reflux Disease ADReCS
General Nutrition Disorder MetaADEDB
Gingival Pain MetaADEDB
Glaucoma ADReCS
Globulins Increased MetaADEDB
Gout MetaADEDB
Grand Mal Convulsion ADReCS
Granulocyte Count Increased MetaADEDB
Haematuria ADReCS
Haemoglobin ADReCS
Haemolytic Anaemia MetaADEDB
Haemoptysis ADReCS
Haemorrhage ADReCS
Haemorrhage Intracranial ADReCS
Haemorrhoids MetaADEDB
Hallucination ADReCS
Hallucinations MetaADEDB
Headache ADReCS
Hearing Impaired ADReCS
Heart Valve Replacement MetaADEDB
Hemiplegia ADReCS
Hepatic Calcification MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Failure ADReCS
Hepatic Function Abnormal ADReCS
Hepatic Lesion MetaADEDB
Hepatitis ADReCS
Hepatitis A MetaADEDB
Hepatitis Cholestatic ADReCS
Hepatobiliary Disease SIDER
Hepatocellular Injury MetaADEDB
Hepatotoxicity MetaADEDB
Hernia Hiatus Repair MetaADEDB
Herpes Simplex MetaADEDB
Hidradenitis MetaADEDB
High Density Lipoprotein Decreased MetaADEDB
Hip Fracture MetaADEDB
Hormone Level Abnormal SIDER
Hot Flash MetaADEDB
Huntington Chorea MetaADEDB
Hyperacusia MetaADEDB
Hyperadrenalism MetaADEDB
Hyperalgesia MetaADEDB
Hyperbaric Oxygen Therapy MetaADEDB
Hyperglycaemia ADReCS
Hyperkinesia ADReCS
Hyperkinesis MetaADEDB
Hyperlipidaemia ADReCS
Hyperproteinaemia MetaADEDB
Hypersensitivity ADReCS
Hypertension ADReCS
Hypertonia ADReCS
Hypertonic Bladder MetaADEDB
Hypoacusis ADReCS
Hypoaesthesia ADReCS
Hypoalbuminaemia MetaADEDB
Hypoglycaemia ADReCS
Hypoglycaemic Seizure MetaADEDB
Hypokinesia ADReCS
Hyponatraemia ADReCS
Hypophosphataemia MetaADEDB
Hypotension ADReCS
Hypothermia ADReCS
Hypovolaemia MetaADEDB
Hysterectomy MetaADEDB
Ileus ADReCS
Ill-Defined Disorder ADReCS
Impaired Healing MetaADEDB
Impotence ADReCS
Inappropriate Antidiuretic Hormone Secretion SIDER
Incontinence ADReCS
Increased Appetite ADReCS
Infarction ADReCS
Infection ADReCS
Infection Urinary Tract MetaADEDB
Infestation SIDER
Infestation Nos SIDER
Influenza ADReCS
Influenza Like Illness ADReCS
Injection Site Cellulitis MetaADEDB
Injection Site Scab MetaADEDB
Injury ADReCS
Insomnia ADReCS
Insufficiency Renal SIDER
Intermittent Claudication ADReCS
International Normalised Ratio Increased ADReCS
Irritability ADReCS
Jaundice MetaADEDB
Jaw Operation MetaADEDB
Joint Effusion MetaADEDB
Kidney Function Abnormal ADReCS
Laceration MetaADEDB
Lack Of Spontaneous Speech MetaADEDB
Lacrimal Disorder ADReCS
Lacrimation SIDER
Lacrimation Increased ADReCS
Learning Disorders MetaADEDB
Left Ventricular Dysfunction MetaADEDB
Legal Problem MetaADEDB
Lethargy ADReCS
Leukopenia ADReCS
Lewy Body Disease MetaADEDB
Libido Increased ADReCS
Liver Function Test Abnormal PROTECT
Loss Of Consciousness ADReCS
Lung Cancer Metastatic MetaADEDB
Lyme Disease MetaADEDB
Lymphadenopathy ADReCS
Lymphadenopathy Mediastinal MetaADEDB
Macular Degeneration ADReCS
Macule ADReCS
Major Depression MetaADEDB
Malaise ADReCS
Malignant Syndrome Nos SIDER
Mastication Disorder MetaADEDB
Mediastinal Disorder SIDER
Melaena ADReCS
Memory Disorders MetaADEDB
Meningioma Benign MetaADEDB
Meningioma Surgery MetaADEDB
Menstrual Disorder MetaADEDB
Mental Disability ADReCS
Mental Disorder SIDER
Mental Disorder Due To A General Medical Condition ADReCS
Mental Impairment MetaADEDB
Mental Status Changes MetaADEDB
Methaemoglobinaemia MetaADEDB
Micturition Urgency MetaADEDB
Migraine Disorders MetaADEDB
Mitochondrial Myopathy MetaADEDB
Monocyte Percentage Decreased MetaADEDB
Monocyte Percentage Increased MetaADEDB
Mood Swings ADReCS
Mouth Ulcer MetaADEDB
Movement Disorders MetaADEDB
Mucosal Dryness MetaADEDB
Multiple Drug Overdose Intentional MetaADEDB
Multiple Injuries MetaADEDB
Multiple Sclerosis MetaADEDB
Muscle Contractions Involuntary ADReCS
Muscle Inflammation MetaADEDB
Muscle Injury MetaADEDB
Muscle Spasticity ADReCS
Muscle Strain MetaADEDB
Muscular Diseases MetaADEDB
Musculoskeletal Chest Pain MetaADEDB
Musculoskeletal Discomfort ADReCS
Myocardial Infarction ADReCS
Myoclonus ADReCS
Myopia ADReCS
Nail Discolouration MetaADEDB
Nasopharyngitis ADReCS
Nausea ADReCS
Neck Deformity MetaADEDB
Necrosis ADReCS
Neoplasm Recurrence MetaADEDB
Nephrolithiasis MetaADEDB
Nephrostomy MetaADEDB
Nerve Degeneration MetaADEDB
Nervous System Disorder SIDER
Nervousness ADReCS
Neuralgia ADReCS
Neuroleptic Malignant Syndrome ADReCS
Neuropathy ADReCS
Neuropathy Peripheral ADReCS
Neurosensory Hypoacusis MetaADEDB
Neurosis ADReCS
Neutropenia ADReCS
Nightmare ADReCS
No Adverse Effect MetaADEDB
Non-Hodgkin Lymphoma Stage Ii MetaADEDB
Non-Small Cell Lung Cancer MetaADEDB
Normal Pressure Hydrocephalus MetaADEDB
Normal Tension Glaucoma MetaADEDB
Normochromic Normocytic Anaemia MetaADEDB
Nuclear Magnetic Resonance Imaging Abnormal MetaADEDB
Nystagmus Pathologic MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Oesophageal Disorder ADReCS
Oesophageal Ulcer ADReCS
Open Angle Glaucoma MetaADEDB
Optic Disc Haemorrhage MetaADEDB
Oral Fungal Infection MetaADEDB
Organic Brain Syndrome SIDER
Orthostatic Hypotension ADReCS
Osteitis Deformans MetaADEDB
Osteoarthritis MetaADEDB
Osteochondroma MetaADEDB
Osteopenia MetaADEDB
Osteosclerosis MetaADEDB
Otitis SIDER
Otitis Media ADReCS
Pain ADReCS
Pain In Extremity ADReCS
Pancreatitis ADReCS
Pancreatitis Acute ADReCS
Pancytopenia ADReCS
Paradoxical Drug Reaction MetaADEDB
Paraesthesia ADReCS
Paranoia ADReCS
Paranoid Reaction SIDER
Parathyroid Tumour Benign MetaADEDB
Parkinsonism ADReCS
Patellofemoral Pain Syndrome MetaADEDB
Peritoneal Adhesions MetaADEDB
Personality Change MetaADEDB
Personality Disorder ADReCS
Pharmaceutical Product Complaint MetaADEDB
Phosphatase Alkaline Increased SIDER
Pleural Adhesion MetaADEDB
Pneumonia ADReCS
Pneumonia Aspiration ADReCS
Pneumonia Staphylococcal MetaADEDB
Poisoning MetaADEDB
Pollakiuria ADReCS
Portal Vein Pressure Increased MetaADEDB
Post Herpetic Neuralgia MetaADEDB
Postictal State MetaADEDB
Postoperative Wound Complication MetaADEDB
Product Tampering MetaADEDB
Prothrombin Time Prolonged MetaADEDB
Pruritus ADReCS
Psychomotor Agitation MetaADEDB
Psychoses Substance-Induced MetaADEDB
Psychotic Disorder ADReCS
Ptosis SIDER
Pulmonary Arterial Hypertension MetaADEDB
Pulmonary Embolism ADReCS
Pulmonary Mass MetaADEDB
Pulmonary Oedema ADReCS
Pulmonary Thrombosis MetaADEDB
Pulpitis Dental MetaADEDB
Pupillary Reflex Impaired MetaADEDB
Purpura ADReCS
Radius Fracture MetaADEDB
Rash ADReCS
Rash Erythematous ADReCS
Rectocele MetaADEDB
Recurrent Cancer MetaADEDB
Refusal Of Treatment By Patient MetaADEDB
Renal Artery Stenosis MetaADEDB
Renal Failure ADReCS
Renal Failure Acute ADReCS
Renal Function Test Abnormal SIDER
Renal Impairment ADReCS
Respiratory Tract Infection ADReCS
Restlessness ADReCS
Resuscitation MetaADEDB
Retinal Detachment ADReCS
Retinal Haemorrhage ADReCS
Rhinorrhea MetaADEDB
Rib Fracture MetaADEDB
Sacroiliitis MetaADEDB
Sarcoidosis MetaADEDB
Scleral Discolouration MetaADEDB
Scoliosis MetaADEDB
Scotoma MetaADEDB
Seizures MetaADEDB
Self Injurious Behaviour MetaADEDB
Sensation Of Heaviness MetaADEDB
Sensory Disturbance MetaADEDB
Sepsis ADReCS
Sexual Activity Increased MetaADEDB
Shock ADReCS
Sinus Disorder MetaADEDB
Skin Disorder ADReCS
Skin Injury MetaADEDB
Skin Laceration MetaADEDB
Skin Neoplasm Excision MetaADEDB
Skin Ulcer ADReCS
Sleep Disorder ADReCS
Sleep Disorders MetaADEDB
Social Problem MetaADEDB
Somnolence ADReCS
Speech Disorder MetaADEDB
Spinal Disorder MetaADEDB
Splenic Cyst MetaADEDB
Spondylitis MetaADEDB
Staring MetaADEDB
Stevens-Johnson Syndrome ADReCS
Stress Fracture MetaADEDB
Stupor ADReCS
Substance Withdrawal Syndrome MetaADEDB
Sudden Death ADReCS
Suicidal Ideation ADReCS
Suicide SIDER
Suicide Attempt ADReCS
Superficial Thrombophlebitis MetaADEDB
Supraventricular Tachycardia ADReCS
Syncope ADReCS
Tachycardia ADReCS
Tardive Dyskinesia ADReCS
Tension ADReCS
Therapeutic Response Unexpected MetaADEDB
Thinking Abnormal ADReCS
Thrombocytopenia ADReCS
Thrombocytopenic Purpura ADReCS
Thrombophlebitis ADReCS
Thrombosis ADReCS
Thrombotic Thrombocytopenic Purpura ADReCS
Tinnitus ADReCS
Tongue Black Hairy MetaADEDB
Tongue Disorder MetaADEDB
Tooth Disease MetaADEDB
Tooth Fracture MetaADEDB
Torsade De Pointes ADReCS
Tracheal Obstruction MetaADEDB
Transient Ischaemic Attack ADReCS
Tremor ADReCS
Trousseau Syndrome MetaADEDB
Ulcer ADReCS
Umbilical Hernia MetaADEDB
Umbilical Hernia Repair MetaADEDB
Underdose MetaADEDB
Underweight MetaADEDB
Upper Limb Fracture MetaADEDB
Upper Respiratory Tract Infection ADReCS
Urethral Disorder SIDER
Urinary Bladder Neurogenic MetaADEDB
Urinary Incontinence ADReCS
Urinary Retention ADReCS
Urinary Tract Disorder SIDER
Urinary Tract Infection ADReCS
Urinary Tract Infection Pseudomonal MetaADEDB
Urinary Tract Operation MetaADEDB
Urine Flow Decreased MetaADEDB
Urticaria ADReCS
Uterovaginal Prolapse ADReCS
Vascular Dementia ADReCS
Vascular Purpura ADReCS
Venous Thrombosis ADReCS
Ventriculo-Peritoneal Shunt MetaADEDB
Vertigo ADReCS
Vibration Test Abnormal MetaADEDB
Vision Blurred ADReCS
Visual Acuity Reduced ADReCS
Vomiting ADReCS
Vulvovaginal Mycotic Infection MetaADEDB
Weight Decreased ADReCS
Weight Loss MetaADEDB
Wrist Fracture MetaADEDB
Xerophthalmia ADReCS

InAADR: Drug-Protein-ADRs database