InAADR

Drug Information

Drug Name: Lasofoxifene (180916-16-9)
PubChem ID: 216416
SMILES: C1CCN(C1)CCOC2=CC=C(C=C2)[C@H]3[C@H](CCC4=C3C=CC(=C4)O)C5=CC=CC=C5
InchiKey: GXESHMAMLJKROZ-IAPPQJPRSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 413.561
LogP: 5.7287
Ring Count: 3
Hydrogen Bond Acceptor Count: 3
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 32.7

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
5'Nucleotidase Increased PROTECT
Abdominal Discomfort PROTECT
Abdominal Pain PROTECT
Abdominal Pain PROTECT
Abdominal Pain PROTECT
Abdominal Tenderness PROTECT
Abnormal Dreams PROTECT
Adenomyosis PROTECT
Adnexa Uteri Cyst PROTECT
Adnexa Uteri Mass PROTECT
Alanine Aminotransferase Increased PROTECT
Alopecia PROTECT
Amnesia PROTECT
Anaemia PROTECT
Anaemia Megaloblastic PROTECT
Anal Fissure PROTECT
Anal Spasm PROTECT
Angioedema PROTECT
Aortic Aneurysm PROTECT
Aphakia PROTECT
Arterial Occlusive Disease PROTECT
Arthritis Infective PROTECT
Arthropathy PROTECT
Aspartate Aminotransferase Increased PROTECT
Back Pain PROTECT
Benign Breast Neoplasm PROTECT
Bile Duct Stone PROTECT
Blood Albumin Decreased PROTECT
Blood Creatinine Abnormal PROTECT
Blood Glucose Increased PROTECT
Blood Triglycerides Increased PROTECT
Blood Urine Present PROTECT
Bone Density Decreased PROTECT
Breast Discharge PROTECT
Breast Disorder Female PROTECT
Breast Engorgement PROTECT
Breast Fibroma PROTECT
Breast Fibrosis PROTECT
Breast Induration PROTECT
Breast Pain PROTECT
Bronchitis PROTECT
Burning Sensation PROTECT
Bursitis PROTECT
Calculus Bladder PROTECT
Capillary Disorder PROTECT
Cardiac Failure PROTECT
Cardiomegaly PROTECT
Cellulitis PROTECT
Cerebral Infarction PROTECT
Cervical Dysplasia PROTECT
Cervical Polyp PROTECT
Cervicitis PROTECT
Cervix Disorder PROTECT
Cheilitis PROTECT
Cheilosis PROTECT
Chest Discomfort PROTECT
Chest Pain PROTECT
Chest X-Ray Abnormal PROTECT
Cholecystitis PROTECT
Cholelithiasis PROTECT
Chorioretinopathy PROTECT
Chronic Lymphocytic Leukaemia PROTECT
Chronic Obstructive Pulmonary Disease PROTECT
Clubbing PROTECT
Coccydynia PROTECT
Colitis Ulcerative PROTECT
Colpocele PROTECT
Conjunctival Haemorrhage PROTECT
Conjunctival Hyperaemia PROTECT
Constipation PROTECT
Cor Pulmonale PROTECT
Costochondritis PROTECT
Cough PROTECT
Cyclothymic Disorder PROTECT
Cystocele PROTECT
Dactylitis PROTECT
Decreased Appetite PROTECT
Deep Vein Thrombosis PROTECT
Dementia Alzheimer Type PROTECT
Diabetes Mellitus PROTECT
Diverticulitis PROTECT
Dizziness Postural PROTECT
Dry Eye PROTECT
Dry Mouth PROTECT
Dry Skin PROTECT
Duodenal Ulcer PROTECT
Duodenitis PROTECT
Dysgeusia PROTECT
Dysphagia PROTECT
Ear Discomfort PROTECT
Electrocardiogram T Wave Abnormal PROTECT
Embolism PROTECT
Endometrial Disorder PROTECT
Endometrial Hyperplasia PROTECT
Endometrial Hypertrophy PROTECT
Endometrial Neoplasm PROTECT
Enlarged Clitoris PROTECT
Epilepsy PROTECT
Erythema PROTECT
Excoriation PROTECT
Exostosis PROTECT
Extremity Contracture PROTECT
Eye Haemorrhage PROTECT
Eye Pruritus PROTECT
Eyelid Oedema PROTECT
Fallopian Tube Cyst PROTECT
Fatigue PROTECT
Feeling Drunk PROTECT
Feeling Hot PROTECT
Female Reproductive Neoplasm PROTECT
Fibroma PROTECT
Flatulence PROTECT
Flushing PROTECT
Fungal Infection PROTECT
Furuncle PROTECT
Gamma-Glutamyltransferase Increased PROTECT
Gastric Polyps PROTECT
Gastritis PROTECT
Genital Candidiasis PROTECT
Genital Discharge PROTECT
Genital Haemorrhage PROTECT
Genital Injury PROTECT
Haemangioma PROTECT
Haemarthrosis PROTECT
Haematoma PROTECT
Haemorrhage PROTECT
Hair Texture Abnormal PROTECT
Headache PROTECT
Hepatic Cancer PROTECT
Hepatic Steatosis PROTECT
Hepatitis PROTECT
Hepatitis B Surface Antigen Positive PROTECT
High Density Lipoprotein Decreased PROTECT
Hot Flush PROTECT
Hydrocephalus PROTECT
Hydrometra PROTECT
Hypercalciuria PROTECT
Hyperhidrosis PROTECT
Hyperparathyroidism PROTECT
Hyperthermia PROTECT
Hypertonic Bladder PROTECT
Hypertriglyceridaemia PROTECT
Hypoalbuminaemia PROTECT
Hypochromasia PROTECT
Hypogeusia PROTECT
Hypophosphataemia PROTECT
Impetigo PROTECT
Increased Appetite PROTECT
Inflammation PROTECT
Inguinal Hernia PROTECT
Inner Ear Disorder PROTECT
Intermittent Claudication PROTECT
Irritable Bowel Syndrome PROTECT
Jaundice PROTECT
Joint Stiffness PROTECT
Labyrinthitis PROTECT
Leiomyoma PROTECT
Limb Injury PROTECT
Liver Disorder PROTECT
Low Density Lipoprotein Increased PROTECT
Lymphostasis PROTECT
Macrocytosis PROTECT
Macular Degeneration PROTECT
Malformation Venous PROTECT
Mass PROTECT
Melanocytic Naevus PROTECT
Memory Impairment PROTECT
Metrorrhagia PROTECT
Micturition Urgency PROTECT
Migraine PROTECT
Migraine With Aura PROTECT
Motor Neurone Disease PROTECT
Mouth Ulceration PROTECT
Muscle Contracture PROTECT
Muscle Spasms PROTECT
Muscle Twitching PROTECT
Musculoskeletal Discomfort PROTECT
Nail Disorder PROTECT
Neck Pain PROTECT
Neoplasm PROTECT
Nephrosclerosis PROTECT
Nerve Compression PROTECT
Night Sweats PROTECT
Nipple Disorder PROTECT
Nipple Pain PROTECT
Nocturia PROTECT
Ocular Hyperaemia PROTECT
Oedema PROTECT
Oedema Peripheral PROTECT
Oesophagitis PROTECT
Onychoclasis PROTECT
Ophthalmic Herpes Simplex PROTECT
Oral Pain PROTECT
Pain In Extremity PROTECT
Pain In Jaw PROTECT
Palpitations PROTECT
Parathyroid Tumour Benign PROTECT
Paresis PROTECT
Pedal Pulse Decreased PROTECT
Periarthritis PROTECT
Perineal Injury PROTECT
Phlebitis PROTECT
Photosensitivity Reaction PROTECT
Plasma Cell Myeloma PROTECT
Platelet Count Decreased PROTECT
Pollakiuria PROTECT
Polyp PROTECT
Postmenopausal Haemorrhage PROTECT
Presyncope PROTECT
Pruritus PROTECT
Pruritus Generalised PROTECT
Pruritus Genital PROTECT
Pulmonary Embolism PROTECT
Pulmonary Granuloma PROTECT
Pupils Unequal PROTECT
Pyelonephritis PROTECT
Pyometra PROTECT
Rash Maculo-Papular PROTECT
Rash Pruritic PROTECT
Rectal Polyp PROTECT
Rectal Ulcer PROTECT
Rectocele PROTECT
Restless Legs Syndrome PROTECT
Retinal Detachment PROTECT
Retinal Vascular Disorder PROTECT
Retinal Vein Thrombosis PROTECT
Retinopathy PROTECT
Rheumatoid Arthritis PROTECT
Rhinitis Allergic PROTECT
Rosacea PROTECT
Rotator Cuff Syndrome PROTECT
Sciatica PROTECT
Seasonal Allergy PROTECT
Sinus Arrest PROTECT
Skeletal Injury PROTECT
Skin Hyperpigmentation PROTECT
Skin Irritation PROTECT
Skin Lesion PROTECT
Skin Oedema PROTECT
Smear Cervix Abnormal PROTECT
Soft Tissue Injury PROTECT
Spinal Fracture PROTECT
Supraventricular Extrasystoles PROTECT
Tachycardia PROTECT
Tenosynovitis PROTECT
Tetany PROTECT
Therapeutic Response Unexpected PROTECT
Thoracic Vertebral Fracture PROTECT
Thrombocytopenia PROTECT
Thrombophlebitis PROTECT
Thrombophlebitis Superficial PROTECT
Thrombosis PROTECT
Tooth Fracture PROTECT
Transaminases Increased PROTECT
Tricuspid Valve Incompetence PROTECT
Type 2 Diabetes Mellitus PROTECT
Ultrasound Breast Abnormal PROTECT
Ultrasound Ovary Abnormal PROTECT
Urethral Disorder PROTECT
Urethral Haemorrhage PROTECT
Urinary Bladder Polyp PROTECT
Urinary Incontinence PROTECT
Urinary Tract Disorder PROTECT
Urinary Tract Infection PROTECT
Urticaria PROTECT
Uterine Cervical Erosion PROTECT
Uterine Cervical Squamous Metaplasia PROTECT
Uterine Haemorrhage PROTECT
Uterine Leiomyoma PROTECT
Uterine Mass PROTECT
Uterine Polyp PROTECT
Uterine Prolapse PROTECT
Vaginal Discharge PROTECT
Vaginal Disorder PROTECT
Vaginal Erosion PROTECT
Vaginal Haemorrhage PROTECT
Vaginal Infection PROTECT
Vaginal Inflammation PROTECT
Vaginal Prolapse PROTECT
Vaginal Wall Congestion PROTECT
Varicose Veins Vulval PROTECT
Vascular Headache PROTECT
Vascular Stenosis PROTECT
Vasomotor Rhinitis PROTECT
Venous Insufficiency PROTECT
Venous Thrombosis PROTECT
Venous Thrombosis Limb PROTECT
Vertigo Positional PROTECT
Visual Acuity Reduced PROTECT
Visual Impairment PROTECT
Vulval Disorder PROTECT
Vulvovaginal Candidiasis PROTECT
Vulvovaginal Pain PROTECT
Vulvovaginal Pruritus PROTECT
Vulvovaginitis PROTECT
Weight Increased PROTECT

InAADR: Drug-Protein-ADRs database