InAADR

Drug Information

Drug Name: Caspofungin (179463-17-3)
PubChem ID: 16119814
SMILES: CCC(C)CC(C)CCCCCCCCC(=O)NC1CC(C(NC(=O)C2C(CCN2C(=O)C(NC(=O)C(NC(=O)C3CC(CN3C(=O)C(NC1=O)C(C)O)O)C(C(C4=CC=C(C=C4)O)O)O)C(CCN)O)O)NCCN)O
InchiKey: JYIKNQVWKBUSNH-WVDDFWQHSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 1093.33
LogP: -3.3119
Ring Count: 1
Hydrogen Bond Acceptor Count: 18
Hydrogen Bond Donor Count: 16
Total Polar Surface Area: 412.03

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Discomfort PROTECT
Abdominal Distension ADReCS
Abdominal Infection MetaADEDB
Abdominal Pain ADReCS
Abdominal Pain ADReCS
Abscess MetaADEDB
Abscess Fungal MetaADEDB
Acquired Diaphragmatic Eventration MetaADEDB
Activated Partial Thromboplastin Time Prolonged PROTECT
Acute Kidney Failure MetaADEDB
Acute Respiratory Distress Syndrome SIDER
Adult Respiratory Distress Syndrome ADReCS
Afib MetaADEDB
Alanine Aminotransferase Increased ADReCS
Alkaline Phosphatase Increased ADReCS
Alkaline Phosphatase Serum Increased SIDER
Alkalosis Hypochloraemic MetaADEDB
Anaemia ADReCS
Anaemia Of Chronic Disease MetaADEDB
Anal Fistula MetaADEDB
Anaphylactic Reaction PROTECT
Anaphylactic Shock ADReCS
Anorexia ADReCS
Anticonvulsant Drug Level Above Therapeutic MetaADEDB
Anxiety ADReCS
Arrhythmia ADReCS
Arthralgia ADReCS
Ascites PROTECT
Aspartate Aminotransferase Increased ADReCS
Aspergillosis ADReCS
Asphyxia MetaADEDB
Aspiration Bone Marrow MetaADEDB
Aspiration Tracheal Abnormal MetaADEDB
Asthenia ADReCS
Atrial Fibrillation ADReCS
Autoimmune Hepatitis MetaADEDB
Back Pain ADReCS
Bacteraemia ADReCS
Bacteria Stool Identified MetaADEDB
Basal Ganglion Degeneration MetaADEDB
Bicarbonate Decreased Serum SIDER
Bilirubin Conjugated Increased PROTECT
Bilirubin Total Increased SIDER
Blood Albumin Decreased ADReCS
Blood Alkaline Phosphatase Increased ADReCS
Blood Bicarbonate Decreased ADReCS
Blood Bilirubin Abnormal MetaADEDB
Blood Bilirubin Increased ADReCS
Blood Calcium Decreased PROTECT
Blood Calcium Increased PROTECT
Blood Chloride Decreased PROTECT
Blood Chloride Increased PROTECT
Blood Creatinine Increased ADReCS
Blood Electrolytes Decreased MetaADEDB
Blood Glucose Increased ADReCS
Blood Magnesium Decreased ADReCS
Blood Phosphorus Decreased PROTECT
Blood Phosphorus Increased ADReCS
Blood Potassium Decreased ADReCS
Blood Potassium Increased ADReCS
Blood Pressure Increased PROTECT
Blood Sodium Decreased PROTECT
Blood Sodium Increased PROTECT
Blood Stem Cell Transplant Failure MetaADEDB
Blood Urea Increased ADReCS
Blood Uric Acid Decreased PROTECT
Blood Urine Present PROTECT
Body Temperature Increased ADReCS
Bone Marrow Toxicity MetaADEDB
Bone Marrow Transplant MetaADEDB
Bone Pain PROTECT
Bowel Sounds Abnormal MetaADEDB
Bradycardia ADReCS
Brain Natriuretic Peptide Increased MetaADEDB
Brain Oedema MetaADEDB
Breath Sounds Abnormal PROTECT
Bronchial Fistula MetaADEDB
Bronchospasm ADReCS
Carbon Dioxide Decreased PROTECT
Cardiac Arrest ADReCS
Cardiac Failure Congestive PROTECT
Catheter Related Infection MetaADEDB
Catheter Site Erythema MetaADEDB
Catheter Site Infection MetaADEDB
Catheter Site Pain PROTECT
Central Line Infection ADReCS
Chest Discomfort PROTECT
Chest Pain PROTECT
Chest X-Ray Abnormal MetaADEDB
Chills ADReCS
Cholecystitis Acute MetaADEDB
Cholestasis PROTECT
Chorioretinitis MetaADEDB
Clostridial Infection MetaADEDB
Clostridium Colitis MetaADEDB
Coagulopathy ADReCS
Colon Neoplasm MetaADEDB
Computerised Tomogram MetaADEDB
Confusional State ADReCS
Constipation ADReCS
Convulsion ADReCS
Corneal Infection MetaADEDB
Cough ADReCS
Creatinine Increased SIDER
Culture Stool Positive MetaADEDB
Cytomegalovirus Antigen MetaADEDB
Decreased Appetite ADReCS
Decubitus Ulcer ADReCS
Depression ADReCS
Dermatitis ADReCS
Dermatitis Allergic PROTECT
Diarrhoea ADReCS
Diffuse Alveolar Damage MetaADEDB
Discomfort ADReCS
Disorientation PROTECT
Dizziness ADReCS
Drug Effect Decreased MetaADEDB
Dry Mouth PROTECT
Dysgeusia PROTECT
Dyspepsia ADReCS
Dysphagia PROTECT
Dyspnoea ADReCS
Dyspnoea Paroxysmal Nocturnal PROTECT
Electrocardiogram T Wave Abnormal MetaADEDB
Electrolyte Imbalance PROTECT
Encephalitis Cytomegalovirus MetaADEDB
Encephalitis Fungal MetaADEDB
Eosinophil Count Increased PROTECT
Eosinophilia ADReCS
Epistaxis ADReCS
Erysipeloid MetaADEDB
Erythema ADReCS
Erythema Multiforme ADReCS
Escherichia Infection MetaADEDB
Excess Potassium MetaADEDB
Exophthalmos MetaADEDB
Eyelid Oedema PROTECT
Face Oedema PROTECT
Failure To Anastomose MetaADEDB
Fatigue ADReCS
Febrile Neutropenia ADReCS
Feeling Abnormal ADReCS
Feeling Cold PROTECT
Feeling Hot ADReCS
Feeling Of Body Temperature Change PROTECT
Flatulence PROTECT
Fluid Overload ADReCS
Flushing ADReCS
Fungus Serology Test Positive MetaADEDB
Gamma-Glutamyltransferase Increased PROTECT
Gastritis ADReCS
Gastrointestinal Obstruction MetaADEDB
Gastrointestinal Pain ADReCS
Genital Rash MetaADEDB
Graft Versus Host Disease ADReCS
Haematocrit Decreased ADReCS
Haematological Malignancy ADReCS
Haematuria ADReCS
Haemodialysis MetaADEDB
Haemoglobin Decreased ADReCS
Headache ADReCS
Hepatic Artery Thrombosis MetaADEDB
Hepatic Enzyme Increased ADReCS
Hepatic Failure ADReCS
Hepatic Function Abnormal ADReCS
Hepatic Necrosis ADReCS
Hepatic Neoplasia MetaADEDB
Hepatomegaly ADReCS
Hepatotoxicity ADReCS
Herpes Simplex MetaADEDB
Hot Flush PROTECT
Hyperbilirubinaemia ADReCS
Hypercalcaemia ADReCS
Hyperglycaemia ADReCS
Hyperhidrosis ADReCS
Hypersensitivity PROTECT
Hypertension ADReCS
Hypoaesthesia PROTECT
Hypocalcaemia PROTECT
Hypokalaemia ADReCS
Hypomagnesaemia ADReCS
Hypotension ADReCS
Hypovolaemic Shock MetaADEDB
Hypoxia ADReCS
Ill-Defined Disorder ADReCS
Immunodeficiency MetaADEDB
Immunosuppressant Drug Level Increased PROTECT
Impaired Gastric Emptying MetaADEDB
Incoherent MetaADEDB
Induration ADReCS
Influenza ADReCS
Infusion Related Reaction ADReCS
Infusion Site Erythema PROTECT
Infusion Site Extravasation PROTECT
Infusion Site Induration PROTECT
Infusion Site Irritation PROTECT
Infusion Site Pain PROTECT
Infusion Site Phlebitis PROTECT
Infusion Site Pruritus PROTECT
Infusion Site Rash PROTECT
Infusion Site Swelling PROTECT
Infusion Site Urticaria PROTECT
Injection Site Erythema PROTECT
Injection Site Oedema PROTECT
Injection Site Pain PROTECT
Injection Site Phlebitis PROTECT
Injection Site Swelling PROTECT
Insomnia ADReCS
Insufficiency Renal SIDER
International Normalised Ratio Increased PROTECT
Intracranial Haematoma MetaADEDB
Intracranial Tumour Haemorrhage MetaADEDB
Jaundice ADReCS
Lacrimation Increased PROTECT
Large Intestinal Haemorrhage MetaADEDB
Leukopenia PROTECT
Lip Erosion MetaADEDB
Liver Disorder PROTECT
Lung Abscess MetaADEDB
Lung Edema MetaADEDB
Lung Infiltration PROTECT
Lung Injury MetaADEDB
Lung Neoplasm MetaADEDB
Lymphangitis MetaADEDB
Lymphocyte Count Decreased PROTECT
Malabsorption MetaADEDB
Malaise ADReCS
Mechanical Ventilation Complication MetaADEDB
Metabolic Acidosis PROTECT
Monocyte Percentage Decreased MetaADEDB
Mouth Bleeding MetaADEDB
Mucosal Haemorrhage MetaADEDB
Mucosal Inflammation ADReCS
Muscular Weakness PROTECT
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Myocardial Infarction ADReCS
Nasal Congestion PROTECT
Nasal Sinus Congestion MetaADEDB
Nausea ADReCS
Neoplasm ADReCS
Neoplasm Malignant ADReCS
Nephropathy Toxic ADReCS
Neutropenia ADReCS
Neutrophil Count Decreased PROTECT
Nikolsky Sign MetaADEDB
Nosocomial Infection MetaADEDB
Nuclear Magnetic Resonance Imaging Abnormal MetaADEDB
Ocular Icterus PROTECT
Oedema ADReCS
Oedema Peripheral ADReCS
Oesophageal Infection MetaADEDB
Opportunistic Infection MetaADEDB
Oral Disorder MetaADEDB
Orbital Infection MetaADEDB
Oropharyngeal Candidiasis ADReCS
Oropharyngeal Pain PROTECT
Pain ADReCS
Pain In Extremity ADReCS
Palpitations PROTECT
Pancreatitis ADReCS
Paraesthesia ADReCS
Paronychia MetaADEDB
Parophthalmia MetaADEDB
Pericarditis MetaADEDB
Periorbital Oedema ADReCS
Periostitis MetaADEDB
Petechiae ADReCS
Ph Urine Increased PROTECT
Phlebitis ADReCS
Phosphatase Alkaline Increased SIDER
Phosphate Increased SIDER
Platelet Count Decreased PROTECT
Platelet Count Increased PROTECT
Pleural Effusion ADReCS
Pneumonia ADReCS
Pneumonia Viral MetaADEDB
Post Procedural Complication MetaADEDB
Potassium Increased SIDER
Potassium Low SIDER
Protein Total Decreased ADReCS
Protein Urine Present ADReCS
Prothrombin Level Increased MetaADEDB
Prothrombin Time Prolonged PROTECT
Prothrombin Time Shortened PROTECT
Pruritus ADReCS
Pruritus Generalised PROTECT
Pulmonary Oedema ADReCS
Pyrexia ADReCS
Rales ADReCS
Rash ADReCS
Rash Erythematous PROTECT
Rash Generalised PROTECT
Rash Macular PROTECT
Rash Maculo-Papular PROTECT
Rash Morbilliform PROTECT
Rash Pruritic PROTECT
Red Blood Cells Urine Positive ADReCS
Renal Cyst MetaADEDB
Renal Failure ADReCS
Renal Failure Acute PROTECT
Renal Impairment ADReCS
Respiratory Distress ADReCS
Respiratory Failure ADReCS
Respiratory Syncytial Virus Infection MetaADEDB
Sensation Of Warmth SIDER
Sepsis ADReCS
Sepsis Syndrome MetaADEDB
Septic Shock ADReCS
Serratia Infection MetaADEDB
Serum Bilirubin Increased SIDER
Serum Creatinine Increased SIDER
Serum Phosphate Increased ADReCS
Serum Potassium Decreased SIDER
Serum Potassium Increased SIDER
Sickness SIDER
Sinus Operation MetaADEDB
Skin Exfoliation ADReCS
Skin Lesion ADReCS
Solid Tumour SIDER
Somnolence ADReCS
Sputum Culture Positive MetaADEDB
Staphylococcal Bacteraemia MetaADEDB
Stem Cell Transplant MetaADEDB
Stevens-Johnson Syndrome ADReCS
Surgical Procedure Repeated MetaADEDB
Sweating SIDER
Sweating Increased SIDER
Swelling ADReCS
Swelling Face ADReCS
T-Cell Lymphoma MetaADEDB
Tachycardia ADReCS
Tachypnoea ADReCS
Tenderness PROTECT
Therapeutic Response Unexpected MetaADEDB
Thrombocytopenia ADReCS
Thrombophlebitis ADReCS
Tracheal Ulcer MetaADEDB
Tracheostomy MetaADEDB
Tremor ADReCS
Ultrasound Abdomen Abnormal MetaADEDB
Unresponsive To Pain Stimuli MetaADEDB
Urea Increased SIDER
Ureterostomy Site Discomfort MetaADEDB
Urinary Casts PROTECT
Urinary Protein Increased SIDER
Urinary Tract Infection ADReCS
Urinary Tract Infection Enterococcal MetaADEDB
Urine Sodium Abnormal MetaADEDB
Urticaria ADReCS
Vaccination Failure MetaADEDB
Vasculitis ADReCS
Vein Disorder MetaADEDB
Vision Blurred PROTECT
Vomiting ADReCS
Wheezing PROTECT
White Blood Cell Count Decreased ADReCS
White Blood Cell Count Increased PROTECT
White Blood Cells Urine Positive PROTECT
Wound Dehiscence MetaADEDB

InAADR: Drug-Protein-ADRs database