InAADR

Drug Information

Drug Name: Ambrisentan (177036-94-1)
PubChem ID: 6918493
SMILES: CC1=CC(=NC(=N1)O[C@H](C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)C
InchiKey: OUJTZYPIHDYQMC-LJQANCHMSA-N
Therapeutic Category:

Computed Drug Properties

Molecular Weight (dalton): 378.428
LogP: 3.51564
Ring Count: 3
Hydrogen Bond Acceptor Count: 5
Hydrogen Bond Donor Count: 1
Total Polar Surface Area: 81.54

This panel provides information on interacting drugs and their ADRs along with references

Interacting drug Toxicity Interaction Type Mechanism Reference

This panel provides drug-protein interaction and their ADRs along with references

Toxicity Interacting Protein Mechanism Reference

This panel provides drug-food interactions and their ADRs along with references

Food Toxicity Reference

This panel provides information on metabolites and their ADRs along with references

Metabolite Toxicity Place of Metabolism Mechanism Reference

This panel provides information on drug category

Toxicity Source
Abdominal Adhesions MetaADEDB
Abdominal Pain ADReCS
Abnormal Sensation In Eye MetaADEDB
Abscess MetaADEDB
Acute Respiratory Failure MetaADEDB
Adrenal Disorder MetaADEDB
Adverse Drug Effect MetaADEDB
Afib MetaADEDB
Albuminuria ADReCS
Alveolitis Fibrosing MetaADEDB
Anaemia ADReCS
Angina Pectoris ADReCS
Angioedema ADReCS
Ankle Fracture MetaADEDB
Anorexia ADReCS
Anuria MetaADEDB
Aortic Aneurysm SIDER
Aortic Dissection SIDER
Aphagia MetaADEDB
Apoplexy MetaADEDB
Arterial Insufficiency MetaADEDB
Arteriosclerotic Heart Disease MetaADEDB
Arthralgia ADReCS
Asthenia PROTECT
Autoimmune Hepatitis PROTECT
Azotaemia ADReCS
Balance Disorder ADReCS
Bladder Cancer MetaADEDB
Blindness Unilateral MetaADEDB
Blood Blister MetaADEDB
Blood Count Abnormal MetaADEDB
Blood Potassium MetaADEDB
Blood Potassium Increased MetaADEDB
Blood Product Transfusion MetaADEDB
Blood Test Abnormal MetaADEDB
Body Temperature Increased ADReCS
Brain Herniation MetaADEDB
Brain Neoplasm MetaADEDB
Brain Oedema MetaADEDB
Breast Cancer Metastatic MetaADEDB
Breast Disorder SIDER
Bronchitis MetaADEDB
Bronchitis Viral MetaADEDB
Bulging MetaADEDB
Cardiac Decompensation MetaADEDB
Cardiac Disease MetaADEDB
Cardiac Disorder ADReCS
Cardiac Failure ADReCS
Cardiac Flutter MetaADEDB
Cardiac Pain SIDER
Cardiac Valve Replacement Complication MetaADEDB
Catheterisation Cardiac MetaADEDB
Chest Discomfort ADReCS
Chest Pain ADReCS
Choking Sensation MetaADEDB
Chronic Left Ventricular Failure MetaADEDB
Chronic Obstructive Airway Disease MetaADEDB
Chronic Respiratory Failure MetaADEDB
Chronic Sinusitis MetaADEDB
Colonic Polyp MetaADEDB
Complication Of Device Insertion MetaADEDB
Complications Of Transplanted Kidney MetaADEDB
Congenital Heart Disease MetaADEDB
Constipation ADReCS
Cor Pulmonale MetaADEDB
Coronary Artery Bypass MetaADEDB
Cough ADReCS
Cramp Muscle SIDER
Csf Protein MetaADEDB
Deafness ADReCS
Decreased Appetite ADReCS
Dermatitis ADReCS
Diabetes Mellitus Inadequate Control MetaADEDB
Diagnostic Procedure MetaADEDB
Dialysis Device Insertion MetaADEDB
Diarrhoea ADReCS
Discomfort ADReCS
Disorder Lung MetaADEDB
Diverticular Perforation MetaADEDB
Diverticulitis MetaADEDB
Dizziness ADReCS
Dizziness Exertional MetaADEDB
Drug Fever ADReCS
Dyspnoea ADReCS
Ear Discomfort MetaADEDB
Ectopic Pregnancies MetaADEDB
Edema Extremities MetaADEDB
Effusion ADReCS
Ejection Fraction MetaADEDB
Electrocardiogram Change MetaADEDB
Embolism Pulmonary MetaADEDB
Emphysema MetaADEDB
Encephalitic Infection MetaADEDB
Encephalitis Allergic MetaADEDB
Eosinophilia ADReCS
Epistaxis PROTECT
Erythema Nodosum MetaADEDB
Excessive Sleepiness MetaADEDB
Eye Oedema MetaADEDB
Facial Neuralgia MetaADEDB
Fat Tissue Increased MetaADEDB
Fatigue PROTECT
Fistula MetaADEDB
Flu MetaADEDB
Fluid Overload MetaADEDB
Fluid Retention ADReCS
Flushing ADReCS
Fractured Pelvis Nos MetaADEDB
Full Blood Count Decreased MetaADEDB
Gangrene MetaADEDB
Gastritis ADReCS
Gastrointestinal Disorder SIDER
Gastrointestinal Pain ADReCS
Gastrointestinal Sounds Abnormal MetaADEDB
Gastrointestinal Ulcer Haemorrhage MetaADEDB
Gouty Arthritis MetaADEDB
Haematocrit Decreased ADReCS
Haemoglobin ADReCS
Haemoglobin Abnormal MetaADEDB
Haemoglobin Decreased ADReCS
Haemolysis ADReCS
Haemolytic Anaemia MetaADEDB
Haemorrhage ADReCS
Haemorrhage Rectum MetaADEDB
Headache ADReCS
Heart Valve Replacement MetaADEDB
Hepatic Enzyme MetaADEDB
Hepatic Failure ADReCS
Hepatic Function Abnormal ADReCS
Hepatitis ADReCS
Hepatitis C MetaADEDB
Hepatotoxicity ADReCS
Hydropneumothorax MetaADEDB
Hypersensitivity ADReCS
Hypertensive Cardiomyopathy MetaADEDB
Hypertensive Emergency MetaADEDB
Hypertensive Heart Disease MetaADEDB
Hypertransaminasaemia MetaADEDB
Hypocoagulable State MetaADEDB
Hypokalaemia ADReCS
Hypotension ADReCS
Hypoxia MetaADEDB
Immune System Disorder SIDER
Immunisation Reaction MetaADEDB
Immunodeficiency MetaADEDB
Incoherent MetaADEDB
Infection ADReCS
Infestation SIDER
Infestation Nos SIDER
Influenza ADReCS
Inhibitory Drug Interaction MetaADEDB
Insomnia ADReCS
Intestinal Obstruction MetaADEDB
Intestinal Perforation MetaADEDB
Irregular Menstrual Cycle MetaADEDB
Kidney Failure MetaADEDB
Kidney Pain MetaADEDB
Kidney Transplant MetaADEDB
Large Intestinal Haemorrhage MetaADEDB
Legionella MetaADEDB
Liver Injury PROTECT
Liver Transplant MetaADEDB
Localised Infection MetaADEDB
Localised Intraabdominal Fluid Collection MetaADEDB
Lower Gastrointestinal Haemorrhage MetaADEDB
Lower Limb Fracture MetaADEDB
Lung Fibrosis MetaADEDB
Lung Infection MetaADEDB
Lung Neoplasm Malignant MetaADEDB
Lung Transplant MetaADEDB
Lymphadenopathy ADReCS
Mediastinal Disorder SIDER
Megacolon MetaADEDB
Mental Disorder SIDER
Micturition Disorder MetaADEDB
Middle Ear Effusion MetaADEDB
Migraine PROTECT
Muscle Spasms ADReCS
Muscle Tightness MetaADEDB
Muscle Weakness MetaADEDB
Musculoskeletal Discomfort ADReCS
Myalgia ADReCS
Nasal Congestion ADReCS
Nasopharyngitis ADReCS
Nausea ADReCS
Near Syncope MetaADEDB
Nephrectomy MetaADEDB
Neumonia MetaADEDB
Neuromuscular Blockade ADReCS
Nocturia ADReCS
Non-Cardiac Chest Pain MetaADEDB
Ocular Icterus MetaADEDB
Oedema ADReCS
Oedema Peripheral ADReCS
Oesophageal Varices Haemorrhage MetaADEDB
Oliguria ADReCS
Onychomadesis MetaADEDB
Oropharyngeal Blistering MetaADEDB
Ovarian Cancer Metastatic MetaADEDB
Oxygen Saturation Decreased MetaADEDB
Oxygen Supplementation MetaADEDB
Pain ADReCS
Palpitations ADReCS
Pancreatic Insufficiency MetaADEDB
Paraesthesia ADReCS
Paralysis ADReCS
Paraplegia MetaADEDB
Patella Fracture MetaADEDB
Personality Disorder MetaADEDB
Pharyngeal Ulceration MetaADEDB
Pharyngitis ADReCS
Phlebothrombosis MetaADEDB
Pickwickian Syndrome MetaADEDB
Pleural Disorder ADReCS
Pleural Effusion ADReCS
Pneumonia ADReCS
Polycythaemia MetaADEDB
Procedural Pain MetaADEDB
Prothrombin Time Abnormal MetaADEDB
Pruritus ADReCS
Pulmonary Arterial Hypertension MetaADEDB
Pulmonary Arterial Wedge Pressure Increased MetaADEDB
Pulmonary Congestion MetaADEDB
Pulmonary Hypertension ADReCS
Rales ADReCS
Rash ADReCS
Recurrent Cancer MetaADEDB
Red Blood Cells Urine Positive ADReCS
Renal Mass MetaADEDB
Respiratory Failure MetaADEDB
Respiratory Tract Infection ADReCS
Rhinitis ADReCS
Right Heart Failure MetaADEDB
Right Ventricular Failure ADReCS
Rupture Of Spleen MetaADEDB
Sarcoidosis MetaADEDB
Sensation Of Heaviness MetaADEDB
Septic Shock MetaADEDB
Shock Haemorrhagic MetaADEDB
Sickle Cell Anaemia MetaADEDB
Sickle Cell Anaemia With Crisis MetaADEDB
Sinus Congestion PROTECT
Sinus Disorder MetaADEDB
Sinus Headache PROTECT
Sinusitis ADReCS
Skeletal Injury MetaADEDB
Skin Ulcer ADReCS
Sleep Disorder ADReCS
Spinal Osteoarthritis MetaADEDB
Sputum Discoloured MetaADEDB
Surgery MetaADEDB
Syncope PROTECT
Tachycardia ADReCS
Testicular Haemorrhage MetaADEDB
Transaminases Increased ADReCS
Transfusion MetaADEDB
Traumatic Haemorrhage MetaADEDB
Tremor ADReCS
Tricuspid Valve Replacement MetaADEDB
Ulcer ADReCS
Unevaluable Event MetaADEDB
Unresponsive To Stimuli MetaADEDB
Upper Gastrointestinal Bleeding MetaADEDB
Upper Respiratory Tract Congestion PROTECT
Upper Respiratory Tract Infection ADReCS
Upper Respiratory Tract Infection Bacterial MetaADEDB
Urethral Disorder SIDER
Urinary Casts Present ADReCS
Urinary Tract Disorder SIDER
Vaginal Haemorrhage ADReCS
Venous Occlusion MetaADEDB
Ventricular Assist Device Insertion MetaADEDB
Ventricular Failure ADReCS
Vomiting ADReCS
Weight Gain MetaADEDB
Wheezing ADReCS
White Blood Cells Urine Positive ADReCS

InAADR: Drug-Protein-ADRs database